バドラサラ・サミール・レヤド (Sara Samir Reyad Badr) - マイポータル

基本情報

所属: 東京大学大学院工学系研究科化学システム工学専攻

研究者番号: 20842206
ORCID ID: https://orcid.org/0000-0003-4233-1353
J-GLOBAL ID: 202301013685566624
researchmap会員ID: R000055883

論文

Kinetic Study and Model-Based Design Space Determination for a Drug Substance Flow Synthesis Using an Amination Reaction via Nucleophilic Aromatic Substitution

Junu Kim, Yusuke Hayashi, Sara Badr, Kazuya Okamoto, Toshikazu Hakogi, Haruo Furukawa, Satoshi Yoshikawa, Hayao Nakanishi, Hirokazu Sugiyama

Organic Process Research & Development 2024年5月17日
Scenario Analysis of Vaccine Supply for COVID-19 in Japan Using Mathematical Models of Infectious Diseases

Kim, J., Matsunami, K., Ichida, Y., Okamura, K., Badr, S., Sugiyama, H.

Journal of Chemical Engineering of Japan 57(1) 2024年
Roles of mechanistic, data-driven, and hybrid modeling approaches for pharmaceutical process design and operation

Gaddem, M.R., Kim, J., Matsunami, K., Hayashi, Y., Badr, S., Sugiyama, H.

Current Opinion in Chemical Engineering 44 2024年
A Systems Evaluation Model for the Development of Companion Diagnostics and Associated Molecularly Targeted Therapies

Kozue Okamura, Hiroki Tsuchiya, Risa Hamada, Yusuke Hayashi, Sara Badr, Seiichi Ohta, Hirokazu Sugiyama

Journal of Pharmaceutical Innovation 18(4) 2265-2276 2023年12月11日
A Comprehensive Design Approach for Injectable Manufacturing Processes considering New Technologies and Operational Aspects

Masahiro Yamada, Sara Badr, Yusuke Hayashi, Kenichi Zenitani, Kokichi Kubota, Hayao Nakanishi, Hirokazu Sugiyama

JOURNAL OF CHEMICAL ENGINEERING OF JAPAN 56(1) 2023年12月
Hybrid Modeling of an Active Pharmaceutical Ingredient Flow Synthesis in a Ring-Opening Reaction of an Epoxide with a Grignard Reagent

Junu Kim, Yusuke Hayashi, Sara Badr, Kazuya Okamoto, Toshikazu Hakogi, Haruo Furukawa, Satoshi Yoshikawa, Hayao Nakanishi, Hirokazu Sugiyama

Industrial & Engineering Chemistry Research 2023年10月19日
The role of process systems engineering in applying quality by design (QbD) in mesenchymal stem cell production

Isuru A. Udugama, Sara Badr, Keita Hirono, Benedikt X. Scholz, Yusuke Hayashi, Masahiro Kino-oka, Hirokazu Sugiyama

COMPUTERS & CHEMICAL ENGINEERING 172 2023年4月
Surrogate modeling of dissolution behavior toward efficient design of tablet manufacturing processes

Kensaku Matsunami, Tomohiro Miura, Keita Yaginuma, Shuichi Tanabe, Sara Badr, Hirokazu Sugiyama

Computers & Chemical Engineering 171 2023年3月
Hybrid modelling and data-driven parameterization of monoclonal antibody cultivation processes: Shifts in cell metabolic behavior

Sara Badr, Kota Oishi, Kozue Okamura, Sei Murakami, Hirokazu Sugiyama

Computer Aided Chemical Engineering 985-990 2023年
Impact of solvent selection on batch and flow syntheses for heterogeneous hydrogenation in drug substance manufacturing: A model-based analysis

Junu Kim, Yusuke Hayashi, Sara Badr, Hayao Nakanishi, Hirokazu Sugiyama

CHEMICAL ENGINEERING RESEARCH & DESIGN 189 156-166 2023年1月
Mechanistic insights into amination via nucleophilic aromatic substitution

Junu Kim, Yusuke Hayashi, Sara Badr, Kazuya Okamoto, Toshikazu Hakogi, Haruo Furukawa, Satoshi Yoshikawa, Hayao Nakanishi, Hirokazu Sugiyama

Reaction Chemistry & Engineering 8(8) 2060-2070 2023年
Data-driven equipment condition monitoring and reliability assessment for sterile drug product manufacturing: Method and application for an operating facility

Philipp Zurcher, Sara Badr, Stephanie Knuppel, Hirokazu Sugiyama

CHEMICAL ENGINEERING RESEARCH & DESIGN 188 301-314 2022年12月
Data-Driven Approach toward Long-Term Equipment Condition Assessment in Sterile Drug Product Manufacturing

Philipp Zürcher, Sara Badr, Stephanie Knüppel, Hirokazu Sugiyama

ACS Omega 7(41) 36415-36426 2022年10月18日
Hybrid Modeling of CHO Cell Cultivation in Monoclonal Antibody Production with an Impurity Generation Module

Kozue Okamura, Sara Badr, Sei Murakami, Hirokazu Sugiyama

Industrial & Engineering Chemistry Research 61(40) 14898-14909 2022年10月12日
A systematic techno-economic approach to decide between continuous and batch operation modes for injectable manufacturing

Masahiro Yamada, Sara Badr, Isuru A. Udugama, Shouko Fukuda, Manabu Nakaya, Yasuyuki Yoshioka, Hirokazu Sugiyama

INTERNATIONAL JOURNAL OF PHARMACEUTICS 613 2022年2月
Design Framework and Tools for Solid Drug Product Manufacturing Processes

Kensaku Matsunami, Sara Badr, Hirokazu Sugiyama

Springer Optimization and Its Applications 189 393-412 2022年
Integrated design of injectable manufacturing processes considering characteristics of process-and discrete-manufacturing systems

Masahiro Yamada, Isuru A. Udugama, Sara Badr, Kenichi Zenitani, Kokichi Kubota, Hayao Nakanishi, Hirokazu Sugiyama

Computer Aided Chemical Engineering 49 2191-2196 2022年1月
Framework for Designing Solid Drug Product Manufacturing Processes Based on Economic and Quality Assessment

Kensaku Matsunami, Sara Badr, Hirokazu Sugiyama

Computer Aided Chemical Engineering 49 223-228 2022年1月
Techno-economic Assessment of Upstream and Downstream Process Alternatives for the Production of Monoclonal Antibodies

Sara Badr, Kozue Okamura, Nozomi Takahashi, Hirokazu Sugiyama

Computer Aided Chemical Engineering 49 745-750 2022年1月
Hybrid Modelling of CHO-MK Cell Cultivation in Monoclonal Antibody Production

Kozue Okamura, Sara Badr, Sei Murakami, Hirokazu Sugiyama

Computer Aided Chemical Engineering 49 2137-2142 2022年1月

もっとみる

共同研究・競争的資金等の研究課題

Multiscale hybrid modeling for design and operation of freeze-drying processes in biopharmaceutical manufacturing

日本学術振興会科学研究費助成事業若手研究 2022年4月 - 2025年3月

バドラサラ・サミール・レヤド

バドラサラ・サミール・レヤド

基本情報

論文

共同研究・競争的資金等の研究課題

メニュー

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