論文

査読有り 国際誌
2020年7月28日

The associations of BMI with mean diffusivity of basal ganglia among young adults with mild obesity and without obesity.

Scientific reports
  • Hikarua Takeuchi
  • ,
  • Yasuyuki Taki
  • ,
  • Rui Nouchi
  • ,
  • Ryoichi Yokoyama
  • ,
  • Seishu Nakagawa
  • ,
  • Kunio Iizuka
  • ,
  • Kohei Sakaki
  • ,
  • Tsuyoshi Araki
  • ,
  • Takayuki Nozawa
  • ,
  • Shigeyuki Ikeda
  • ,
  • Susumu Yokota
  • ,
  • Sugiko Hanawa
  • ,
  • Daniele Magistro
  • ,
  • Yuka Kotozaki
  • ,
  • Yukako Sasaki
  • ,
  • Kelssy H Dos S Kawata
  • ,
  • Ryuta Kawashima

10
1
開始ページ
12566
終了ページ
12566
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1038/s41598-020-69438-5

Obesity causes a wide range of systemic diseases and is associated with mood and anxiety disorders. It is also associated with dopaminergic reward system function. However, the relationships between microstructural properties of the dopaminergic system and body mass index (BMI) have not been investigated. In this study, we investigated the associations of BMI with mean diffusivity (MD), diffusion tensor imaging measure in areas of the dopaminergic system (MDDS) in 435 healthy young adults with mild obesity and without obesity (BMI < 40). We detected the association between greater BMI and lower MD of the right globus pallidus and the right putamen. These results suggest that the property of the dopaminergic system is associated with BMI among young adults with mild obesity and without obesity.

リンク情報
DOI
https://doi.org/10.1038/s41598-020-69438-5
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/32724120
PubMed Central
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387490
ID情報
  • DOI : 10.1038/s41598-020-69438-5
  • PubMed ID : 32724120
  • PubMed Central 記事ID : PMC7387490

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