論文

査読有り 国際誌
2019年9月1日

Function of myosuppressin in regulating digestive function in the two-spotted cricket, Gryllus bimaculatus.

General and comparative endocrinology
  • Yi Jun Zhou
  • ,
  • Hitomi Seike
  • ,
  • Shinji Nagata

280
開始ページ
185
終了ページ
191
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1016/j.ygcen.2019.05.001

Myosuppressin is one of essential peptides controlling biological processes including feeding behavior. Here we identified and characterized the cDNAs that encode myosuppressin precursor and its receptor in the two-spotted cricket Gryllus bimaculatus. The presence of the mature peptide (Grybi-MS) was confirmed by direct measurement of adult brain. RT-PCR revealed the tissue distribution of these transcripts; myosuppressin is expressed predominantly in the brain and central nervous system, whereas its receptor is ubiquitously expressed in the cricket body. To address the function of Grybi-MS, we performed several bioassays to test concerning feeding behavior and digestive function upon exposure to Grybi-MS. Administration of synthetic Grybi-MS resulted in increased feeding motivation, accompanied by an increase in food intake. Meanwhile, the hemolymph lipid and carbohydrate titers were both elevated after Grybi-MS injection. As the intestinal contraction is significantly inhibited by the exposure to Grybi-MS, the upregulating feeding index might be complicated in the cricket body. The current data indicate that Grybi-MS modulates feeding behavior to control the physiological processes in the cricket.

リンク情報
DOI
https://doi.org/10.1016/j.ygcen.2019.05.001
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/31054903

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