Chemical compositions of spherules separated from deep sea sediment dredged off Hawaiian islands and from Antarctic ice were measured by instrumental neutron activation analysis (INAA) using Kyoto University Reactor (KUR). Iron, cobalt, nickel, iridium, scandium and manganese contents in those spherules were determined to be 19.3-97.7%, 23-4370 mg center dot kg(1), 0.08-7.04%, 0.84-35.4 mg center dot kg(-1), 1.4-44.3 mg center dot kg(-1) stop and 93.4 mg center dot kg(-1-)7.2 %, respectively, and compared with each other. Particularly, iridium was detected in seven spherules among fourteen from Hawaii, but only one spherule among twenty-two from Antarctic, and those spherules turned out to be extraterrestrial in origin. However, it was shown that there was little difference in characteristics of elemental contents between both kinds of spherules, except for Ir-detected spherules.