Kaminishi Tatsuya

Profile Information

Affiliation: Osaka University

J-GLOBAL ID: 201901016202388395
researchmap Member ID: B000365911

Research Interests

Research Areas

Research History

Sep, 2019 - Present

Assistant Professor, Osaka University Graduate School of Medicine Division of Medicine
Mar, 2013 - Aug, 2019

Center for Cooperative Research in Biosciences (CIC bioGUNE)
Dec, 2007 - Jan, 2013

Goethe University Frankfurt

Awards

Apr, 2022

Young Innovator Award, 科学技術振興機構

Papers

HKDC1, a target of TFEB, is essential to maintain both mitochondrial and lysosomal homeostasis, preventing cellular senescence

Mengying Cui, Koji Yamano, Kenichi Yamamoto, Hitomi Yamamoto-Imoto, Satoshi Minami, Takeshi Yamamoto, Sho Matsui, Tatsuya Kaminishi, Takayuki Shima, Monami Ogura …

Proceedings of the National Academy of Sciences, Jan 9, 2024
Microautophagy regulated by STK38 and GABARAPs is essential to repair lysosomes and prevent aging.

Monami Ogura, Tatsuya Kaminishi, Takayuki Shima, Miku Torigata, Nao Bekku, Keisuke Tabata, Satoshi Minami, Kohei Nishino, Akiko Nezu, Maho Hamasaki …

EMBO reports, e57300, Nov 21, 2023
Golgi membrane proteins YIPF3 and YIPF4 regulate turnover of the Golgi apparatus through autophagy

Shinri Kitta, Tatsuya Kaminishi, Momoko Higashi, Takayuki Shima, Hidetaka Kosako, Tamotsu Yoshimori, Akiko Kuma

bioRxiv, Aug 10, 2023
Selective plane activation structured illumination microscopy

Kenta Temma, Ryosuke Oketani, Toshiki Kubo, Kazuki Bando, Shunsuke Maeda, Kazunori Sugiura, Tomoki Matsuda, Rainer Heintzmann, Tatsuya Kaminishi, Koki Fukuda …

bioRxiv, Jun 19, 2023
Orthoformimycin inhibits translation elongation by displacing the A-site tRNA and preventing peptide bond formation

Andreas Schedlbauer, Tatsuya Kaminishi, Attilio Fabbretti, Pohl Milón, Xu Han, Borja Ochoa-Lizarralde, Retina Çapuni, Claudio O. Gualerzi, Sean R. Connell, Paola Fucini

bioRxiv, Nov 29, 2021 Lead author
A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit

Andreas Schedlbauer, Idoia Iturrioz, Borja Ochoa-Lizarralde, Tammo Diercks, Jorge Pedro López-Alonso, José Luis Lavin, Tatsuya Kaminishi, Retina Çapuni, Neha Dhimole, Elisa de Astigarraga …

Science Advances, 7(23) eabf7547-eabf7547, Jun 4, 2021 Peer-reviewed
The third-generation tetracycline, KBP-7072, exploits and reveals a new potential of the primary tetracycline binding pocket

Tatsuya Kaminishi, Andreas Schedlbauer, Borja Ochoa-Lizarralde, Elisa de Astigarraga, Retina Çapuni, Fred Yang, Vincent Benn, Qingmei Liu, Xiaojuan Tan, Min Zhang …

bioRxiv, Dec 31, 2018 Lead author
Establishing a data screening strategy for X-ray crystallography of a supramacromolecular complex

Masahito Kawazoe, Fumikazu Konishi, Tatsuya Kaminishi, Takashi Itagaki, Ryogo Akasaka, Chie Takemoto

HPCI Research Report, 3 58-66, Dec 10, 2018 Peer-reviewed
RsgA couples the maturation state of the 30S ribosomal decoding center to activation of its GTPase pocket.

Jorge Pedro López-Alonso, Tatsuya Kaminishi, Takeshi Kikuchi, Yuya Hirata, Idoia Iturrioz, Neha Dhimole, Andreas Schedlbauer, Yoichi Hase, Simon Goto, Daisuke Kurita …

Nucleic acids research, 45(11) 6945-6959, Jun 20, 2017 Peer-reviewed
Structure of a 30S pre-initiation complex stalled by GE81112 reveals structural parallels in bacterial and eukaryotic protein synthesis initiation pathways.

Jorge P López-Alonso, Attilio Fabbretti, Tatsuya Kaminishi, Idoia Iturrioz, Letizia Brandi, David Gil-Carton, Claudio O Gualerzi, Paola Fucini, Sean R Connell

Nucleic acids research, 45(4) 2179-2187, Feb 28, 2017 Peer-reviewed
Inhibition of translation initiation complex formation by GE81112 unravels a 16S rRNA structural switch involved in P-site decoding.

Attilio Fabbretti, Andreas Schedlbauer, Letizia Brandi, Tatsuya Kaminishi, Anna Maria Giuliodori, Raffaella Garofalo, Borja Ochoa-Lizarralde, Chie Takemoto, Shigeyuki Yokoyama, Sean R Connell …

Proceedings of the National Academy of Sciences of the United States of America, 113(16) E2286-95, Apr 19, 2016 Peer-reviewed
Crystallographic characterization of the ribosomal binding site and molecular mechanism of action of Hygromycin A.

Tatsuya Kaminishi, Andreas Schedlbauer, Attilio Fabbretti, Letizia Brandi, Borja Ochoa-Lizarralde, Cheng-Guang He, Pohl Milón, Sean R Connell, Claudio O Gualerzi, Paola Fucini

Nucleic acids research, 43(20) 10015-25, Nov 16, 2015 Peer-reviewed
Structural characterization of an alternative mode of tigecycline binding to the bacterial ribosome.

Andreas Schedlbauer, Tatsuya Kaminishi, Borja Ochoa-Lizarralde, Neha Dhimole, Shu Zhou, Jorge P López-Alonso, Sean R Connell, Paola Fucini

Antimicrobial agents and chemotherapy, 59(5) 2849-54, May, 2015 Peer-reviewed
Biochemical evidence for the heptameric complex L10(L12)6 in the Thermus thermophilus ribosome: in vitro analysis of its molecular assembly and functional properties.

Takaomi Nomura, Masato Nakatsuchi, Daiyu Sugita, Mamoru Nomura, Tatsuya Kaminishi, Chie Takemoto, Mikako Shirouzu, Tomohiro Miyoshi, Shigeyuki Yokoyama, Akira Hachimori …

Journal of biochemistry, 144(5) 665-73, Nov, 2008 Peer-reviewed
Structure of an N-terminally truncated selenophosphate synthetase from Aquifex aeolicus.

Eiko Matsumoto, Shun Ichi Sekine, Ryogo Akasaka, Yumi Otta, Kazushige Katsura, Mio Inoue, Tatsuya Kaminishi, Takaho Terada, Mikako Shirouzu, Shigeyuki Yokoyama

Acta crystallographica. Section F, Structural biology and crystallization communications, 64(Pt 6) 453-8, Jun 1, 2008 Peer-reviewed
Crystal structure of human ribosomal protein L10 core domain reveals eukaryote-specific motifs in addition to the conserved fold.

Mitsuhiro Nishimura, Tatsuya Kaminishi, Chie Takemoto, Masahito Kawazoe, Takuya Yoshida, Akiko Tanaka, Sumio Sugano, Mikako Shirouzu, Tadayasu Ohkubo, Shigeyuki Yokoyama …

Journal of molecular biology, 377(2) 421-30, Mar 21, 2008 Peer-reviewed
Structural aspects of RbfA action during small ribosomal subunit assembly.

Partha P Datta, Daniel N Wilson, Masahito Kawazoe, Neil K Swami, Tatsuya Kaminishi, Manjuli R Sharma, Timothy M Booth, Chie Takemoto, Paola Fucini, Shigeyuki Yokoyama …

Molecular cell, 28(3) 434-45, Nov 9, 2007 Peer-reviewed
Purification, crystallization and preliminary X-ray diffraction study of human ribosomal protein L10 core domain.

Mitsuhiro Nishimura, Tatsuya Kaminishi, Masahito Kawazoe, Mikako Shirouzu, Chie Takemoto, Shigeyuki Yokoyama, Akiko Tanaka, Sumio Sugano, Takuya Yoshida, Tadayasu Ohkubo …

Acta crystallographica. Section F, Structural biology and crystallization communications, 63(Pt 11) 950-2, Nov 1, 2007 Peer-reviewed
Structural characterization of the ribosome maturation protein, RimM.

Sakura Suzuki, Ayako Tatsuguchi, Eiko Matsumoto, Masahito Kawazoe, Tatsuya Kaminishi, Mikako Shirouzu, Yutaka Muto, Chie Takemoto, Shigeyuki Yokoyama

Journal of bacteriology, 189(17) 6397-406, Sep, 2007 Peer-reviewed
A snapshot of the 30S ribosomal subunit capturing mRNA via the Shine-Dalgarno interaction.

Tatsuya Kaminishi, Daniel N Wilson, Chie Takemoto, Joerg M Harms, Masahito Kawazoe, Frank Schluenzen, Kyoko Hanawa-Suetsugu, Mikako Shirouzu, Paola Fucini, Shigeyuki Yokoyama

Structure (London, England : 1993), 15(3) 289-97, Mar, 2007 Peer-reviewed

Misc.

リボソーム小サブユニット依存GTPase RsgAの構造解析

竹本千重, LOPEZ-ALONSO JP, 上西達也, 菊地岳志, 平田侑也, ITURRIOZ I, DHIMOLE N, SCHEDLBAUER A, 長谷要一, 後藤史門 …

日本RNA学会年会要旨集, 19th, 2017
リボソームの構造解析における計算科学的アプローチ

川添将仁, 小西史一, KAMINISHI Tatsuya, KAMINISHI Tatsuya, 直枝千恵子, 板垣貴, FUCINI Paola, 竹本千重, 横山茂之

日本RNA学会年会要旨集, 15th, 2013
リボソーム成熟因子RsgA/YjeQの構造機能解析

竹本千重, CONNELL Sean R., CONNELL Sean R., 長谷洋一, 直枝智恵子, WANG Hongfei, 上西達也, 上西達也, 菊池岳志, 平田侑也 …

日本RNA学会年会要旨集, 12th, 2010
リボソームのX線結晶構造解析

川添将仁, 直枝智恵子, 板垣貴, 上西達也, 上西達也, 竹本千重, 横山茂之

PFシンポジウム要旨集, 27th, 2010
超好熱菌A.aeolicusのYjeQの構造機能解析

竹本千重, WANG H., 末次(塙)京子, 上西達也, 上西達也, 川添将仁, 井上みお, 牛越亮子, 寺田貴帆, 白水美香子 …

日本RNA学会年会要旨集, 11th, 2009
Cold-shock protein RbfAとリボソーム複合体の構造解析

竹本千重, 川添将仁, DATTA Partha P., WILSON Daniel N., SWAMI Neil K., 上西達也, SHARMA Manjuli R., BOOTH Timothy M., FUCINI Paola, AGRAWAL Rajendra K. …

PFシンポジウム要旨集, 25th, 2008
リボソーム成熟因子RimMの結晶構造解析

竹本千重, 上西達也, 川添将仁, 鈴木咲良, 龍口文子, 松本英子, 白水美香子, 武藤裕, 横山茂之, 横山茂之

日本RNA学会年会要旨集, 10th, 2008
Kasugamycin blocks the mRNA path on the ribosome: structural basis for the inhibition of translation initiation by kasugamycin

Bioscience & industry, 65(5) 237-241, May, 2007
リボソーム30Sサブユニットと翻訳開始シグナル配列の相互作用

上西達也, WILSON D N, 竹本千重, HARMS J M, 川添将仁, 末次京子, 白水美香子, FUCINI P, 横山茂之, 横山茂之

高度好熱菌丸ごと一匹プロジェクト第6回連携研究会理研シンポジウム平成19年, 2007
リボソームRNA成熟に関わるRibosome-binding factor Aとリボソーム30Sサブユニット複合体の構造解析

川添将仁, DATTA Partha P., WILSON Daniel N., SWAMI Neil K., 上西達也, SHARMA Manjuli R., BOOTH Timothy M., 竹本千重, FUCINI Paola, AGRAWAL Rajendra K. …

生化学, 2007
リボソーム成熟関連タンパク質RimMの構造特性

鈴木咲良, 龍口文子, 松本英子, 川添将仁, 上西達也, 白水美香子, 武藤裕, 竹本千重, 横山茂之, 横山茂之

生化学, 2007
核磁気共鳴法を用いたRimMタンパク質の構造と相互作用解析

川添将仁, 鈴木咲良, 龍口文子, 松本英子, 上西達也, 白水美香子, 武藤裕, 竹本千重, 横山茂之, 横山茂之

高度好熱菌丸ごと一匹プロジェクト第6回連携研究会理研シンポジウム平成19年, 2007
高度好熱菌リボソーム複合体の結晶構造解析

上西達也, 川添将仁, 竹本千重, 齋藤由美, 関根俊一, 白水美香子, WILSON Daniel N., FUCINI Paola, 横山茂之, 横山茂之

PFシンポジウム要旨集, 24th, 2007
The antibiotic kasugamycin mimics mRNA nucleotides to destabilize tRNA binding and inhibit canonical translation initiation (vol 13, pg 871, 2006)

Frank Schluenzen, Chie Takemoto, Daniel N. Wilson, Tatsuya Kaminishi, Joerg M. Harms, Kyoko Hanawa-Suetsugu, Witold Szaflarski, Masahito Kawazoe, Mikako Shirouzu, Knud H. Nierhaus …

NATURE STRUCTURAL & MOLECULAR BIOLOGY, 13(11) 1033-1033, Nov, 2006
抗生物質カスガマイシンと結合した高度好熱菌リボソーム30Sサブユニットの結晶構造

上西達也, SCHLUENZEN Frank, 竹本千重, WILSON Daniel N., HARMS Joerg, 塙(末次)京子, SZAFLARSKI Witold, 川添将仁, NIERHAUS Knud H., 横山茂之 …

日本RNA学会年会要旨集, 8th, 2006
Thermus thermophilus由来L10と三個のL7/L12 stalkダイマーの分子集合に関する生化学的解析

中土雅人, 野村隆臣, 八森章, 野村守, 竹本千重, 白水美香子, 白水美香子, 寺田貴帆, 寺田貴帆, 上西達也 …

日本RNA学会年会要旨集, 8th, 2006
高度好熱菌由来RimMのN末ドメインの溶液構造

鈴木咲良, 龍口文子, 松本英子, 川添将仁, 上西達也, 白水美香子, 武藤裕, 竹本千重, 横山茂之, 横山茂之

Abstracts. Annual Meeting of the NMR Society of Japan, 45th, 2006
Aeropyrum pernix K1のBrixドメインタンパク質の構造解析

川添将仁, 竹本千重, 上西達也, 末次(塙)京子, 白水美香子, 白水美香子, 横山茂之, 横山茂之, 横山茂之

日本分子生物学会年会講演要旨集, 28th, 2005
PrmAの結晶構造から示唆されるリボソームタンパク質L11のメチル化反応における協調的かつ合理的な進行性

上西達也, 酒井宏明, 竹本千重, 寺田貴帆, 中川紀子, 中川紀子, 真岡伸子, 倉光成紀, 倉光成紀, 白水美香子 …

RNAミーティング, 7th, 2005
高度好熱菌Eraの構造と機能の解析

川添将仁, 竹本(堀)千重, 上西達也, 関根俊一, 白水美香子, 横山茂之

日本分子生物学会年会プログラム・講演要旨集, 27th, 2004

Teaching Experience

Jan, 2023 - Jan, 2023

機能性実習 (Osaka University)
Jun, 2022 - Jun, 2022

学問への扉 (Osaka University)
May, 2022 - May, 2022

基礎医学体験実習講義 (Osaka University)
Jun, 2021 - Jul, 2021

学問への扉 (大阪大学)
May, 2021 - May, 2021

基礎医学体験実習講義 (大阪大学)
Jan, 2021 - Jan, 2021

機能性実習 (大阪大学)
Jul, 2020 - Jul, 2020

学問への扉 (大阪大学)
May, 2020 - Jul, 2020

基礎医学体験実習 (大阪大学)
Jan, 2020 - Jan, 2020

機能性実習 (大阪大学)

Professional Memberships

Research Projects

オートファジー抑制因子Rubiconとその阻害剤の機能発現機構の解明

科学研究費助成事業基盤研究(C), 基盤研究(C), 日本学術振興会, Apr, 2020 - Mar, 2024

上西達也
リソソームエキソサイトーシスを制御するCa2+チャネルTRPML1複合体の構造解析

CREST若手チャレンジ, 科学技術振興機構, Apr, 2022 - Mar, 2023
リソソームエキソサイトーシスを制御するCa2+チャネルTRPML1複合体の構造解析

CREST若手チャレンジ, 科学技術振興機構, Apr, 2021 - Mar, 2022
リソソームエキソサイトーシスを制御するCa2+チャネルTRPML1複合体の構造解析

CREST若手チャレンジ, 科学技術振興機構, Jul, 2020 - Mar, 2021

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