Shimazaki, Takuya Last updated: Aug 24, 2019 at 02:53
Name
Shimazaki, Takuya Affiliation
Keio University Section
School of Medicine Department of Physiology Job title
Associate Professor Degree
博士（医学）(東京大学大学院医学系研究科) Research funding number
00324749
Published Papers
SHIMAZAKI TAKUYA
The Keio Journal of Medicine 65(1) 1-15 Feb 2016 [Refereed][Invited]
SHIMAZAKI TAKUYA
NPJ Aging and Mechanisms of Diseases 2 15014 Jan 2016 [Refereed][Invited]
Tsuyama, Jun,Bunt, Jens, Richards, Linda J, Iwanari, Hiroko, Mochizuki, Yasuhiro, Hamakubo, Takao, Shimazaki, Takuya, Okano, Hideyuki
Stem Cell Reports 5(3) 365-377 Sep 2015 [Refereed]
Tomioka, Takeyasu, Shimazaki, Takuya, Yamauchi, Toshihiko, Oki, Toru, Ohgoh, Makoto, Okano, Hideyuki
JOURNAL OF BIOLOGICAL CHEMISTRY 289(2) 1000-1010 Jan 2014 [Refereed]
Naka-Kaneda, Hayato, Nakamura, Shiho, Igarashi, Mana, Aoi, Hisashi, Kanki, Hiroaki, Tsuyama, Jun, Tsutsumi, Shuichi, Aburatani, Hiroyuki, Shimazaki, Takuya, Okano, Hideyuki
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 111(4) 1604-1609 Jan 2014 [Refereed]
Sato, Takuya, Shimazaki, Takuya, Naka, Hayato, Fukami, Shin-Ichi, Satoh, Yasushi, Okano, Hideyuki, Lax, Irit, Schlessinger, Joseph, Gotoh, Noriko
STEM CELLS 28(9) 1660-1672 Sep 2010 [Refereed]
Sakaguchi, Masanori, Imaizumi, Yoichi, Shingo, Tetsuro, Tada, Hirobumi, Hayama, Ko, Yamada, Osamu, Morishita, Tsuyoshi, Kadoya, Toshihiko, Uchiyama, Noboru, Shimazaki, Takuya, Kuno, Atsushi, Poirier, Francoise, Hirabayashi, Jun, Sawamoto, Kazunobu, Okano, Hideyuki
JOURNAL OF NEUROCHEMISTRY 113(6) 1516-1524 Jun 2010 [Refereed]
Ishii, Seiji, Okada, Yohei, Kadoya, Toshihiko, Matsuzaki, Yumi, Shimazaki, Takuya, Okano, Hideyuki
JOURNAL OF NEUROSCIENCE RESEARCH 88(4) 722-734 Mar 2010 [Refereed]
Tao, Osamu, Shimazaki, Takuya, Okada, Yohei, Naka, Hayato, Kohda, Kazuhisa, Yuzaki, Michisuke, Mizusawa, Hidehiro, Okano, Hideyuki
JOURNAL OF NEUROSCIENCE RESEARCH 88(2) 234-247 Feb 2010 [Refereed]
Ogawa, Daisuke, Okada, Yohei, Nakamura, Masaya, Kanemura, Yonehiro, Okano, Hirotaka James, Matsuzaki, Yumi, Shimazaki, Takuya, Ito, Mamoru, Ikeda, Eiji, Tamiya, Takashi, Nagao, Seigo, Okano, Hideyuki
JOURNAL OF NEUROSCIENCE RESEARCH 87(2) 307-317 Feb 2009 [Refereed]
Naka, Hayato, Nakamura, Shiho, Shimazaki, Takuya, Okano, Hideyuki
NATURE NEUROSCIENCE 11(9) 1014-1023 Sep 2008 [Refereed]
Ozawa, Yoko, Nakao, Keiko, Kurihara, Toshihide, Shimazaki, Takuya, Shimmura, Shigeto, Ishida, Susumu, Yoshimura, Akihiko, Tsubota, Kazuo, Okano, Hideyuki
JOURNAL OF BIOLOGICAL CHEMISTRY 283(36) 24561-24570 Sep 2008 [Refereed]
Miyagi, Satoru, Masui, Shinji, Niwa, Hitoshi, Saito, Tetsuichiro, Shimazaki, Takuya, Okano, Hideyuki, Nishimoto, Masazumi, Muramatsu, Masami, Iwama, Atsushi, Okuda, Akihiko
FEBS LETTERS 582(18) 2811-2815 Aug 2008 [Refereed]
Okada, Yohei, Matsumoto, Arifumi, Shimazaki, Takuya, Enoki, Ryosuke, Koizumi, Amane, Ishii, Seiji, Itoyama, Yasuto, Sobue, Gen, Okano, Hideyuki
STEM CELLS 26(12) 3086-3098 2008 [Refereed]
Hayakawa-Yano, Yoshika, Nishida, Keigo, Fukami, Shinichi, Gotoh, Yukiko, Hirano, Toshio, Nakagawa, Toshiyuki, Shimazaki, Takuya, Okano, Hideyuki
STEM CELLS 25(6) 1410-1422 Jun 2007 [Refereed]
Kohno, Daisuke, Nakata, Masanori, Maekawa, Fumihiko, Fujiwara, Ken, Maejima, Yuko, Kuramochi, Motoki, Shimazaki, Takuya, Okano, Hideyuki, Onaka, Tatsushi, Yada, Toshihiko
ENDOCRINOLOGY 148(5) 2251-2263 May 2007 [Refereed]
Ozawa, Yoko, Nakao, Keiko, Shimazaki, Takuya, Shimmura, Shigeto, Kurihara, Toshihide, Ishida, Susumu, Yoshimura, Akihiko, Tsubota, Kazuo, Okano, Hideyuki
DEVELOPMENTAL BIOLOGY 303(2) 591-600 Mar 2007 [Refereed]
Iwata, Naoko, Yoshida, Hiroaki, Tobiume, Minoru, Ono, Fumiko, Shimazaki, Takuya, Sata, Tetsutaro, Nakajima, Noriko
JOURNAL OF NEUROVIROLOGY 13(1) 11-22 2007 [Refereed]
Okada, Seiji, Nakamura, Masaya, Katoh, Hiroyuki, Miyao, Tamaki, Shimazaki, Takuya, Ishii, Ken, Yamane, Junichi, Yoshimura, Akihiko, Iwamoto, Yukihide, Toyama, Yoshiaki, Okano, Hideyuki
NATURE MEDICINE 12(7) 829-834 Jul 2006 [Refereed]
Sakaguchi, M, Shingo, T, Shimazaki, T, Okano, HJ, Shiwa, M, Ishibashi, S, Oguro, H, Ninomiya, M, Kadoya, T, Horie, H, Shibuya, A, Mizusawa, H, Poirier, F, Nakauchi, H, Sawamoto, K, Okano, H
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 103(18) 7112-7117 May 2006 [Refereed]
Fukuhara, Y, Li, XK, Kitazawa, Y, Inagaki, M, Matsuoka, K, Kosuga, M, Kosaki, R, Shimazaki, T, Endo, H, Umezawa, A, Okano, H, Takahashi, T, Okuyama, T
MOLECULAR THERAPY 13(3) 548-555 Mar 2006 [Refereed]
Essential role of Shp2-binding sites on FRS2 alpha for corticogenesis and for FGF2-dependent proliferation of neural progenitor cells
Yamamoto, S, Yoshino, I, Shimazaki, T, Murohashi, M, Hevner, RF, Lax, I, Okano, H, Shibuya, M, Schlessinger, J, Gotoh, N
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 102(44) 15983-15988 Nov 2005 [Refereed]
Suzuki, T, Izumoto, S, Wada, K, Fujimoto, Y, Maruno, M, Yamasaki, M, Kanemura, Y, Shimazaki, T, Okano, H, Yoshimine, T
JOURNAL OF NEURO-ONCOLOGY 74(3) 233-239 Sep 2005 [Refereed]
Tomita, Y, Matsumura, K, Wakamatsu, Y, Matsuzaki, Y, Shibuya, I, Kawaguchi, H, Ieda, M, Kanakubo, S, Shimazaki, T, Ogawa, S, Osumi, N, Okano, H, Fukuda, K
JOURNAL OF CELL BIOLOGY 170(7) 1135-1146 Sep 2005 [Refereed]
Transient inhibition of BMP signaling by Noggin induces cardiomyocyte differentiation of mouse embryonic stem cells
Yuasa, S, Itabashi, Y, Koshimizu, U, Tanaka, T, Sugimura, K, Kinoshita, M, Hattori, F, Fukami, S, Shimazaki, T, Okano, H, Ogawa, S, Fukuda, K
NATURE BIOTECHNOLOGY 23(7) 897-897 Jul 2005 [Refereed]
Nagato, M, Heike, T, Kato, T, Yamanaka, Y, Yoshimoto, M, Shimazaki, T, Okano, H, Nakahata, T
JOURNAL OF NEUROSCIENCE RESEARCH 80(4) 456-466 May 2005 [Refereed]
Uemura, O, Okada, Y, Ando, H, Guedj, M, Higashijima, S, Shimazaki, T, Chino, N, Okano, H, Okamoto, H
DEVELOPMENTAL BIOLOGY 278(2) 587-606 Feb 2005 [Refereed]
Okada, Y, Shimazaki, T, Sobue, G, Okano, H
DEVELOPMENTAL BIOLOGY 275(1) 124-142 Nov 2004 [Refereed]
Ishibashi, S, Sakaguchi, M, Kuroiwa, T, Yamasaki, M, Kanemura, Y, Shizuko, I, Shimazaki, T, Onodera, M, Okano, H, Mizusawa, H
JOURNAL OF NEUROSCIENCE RESEARCH 78(2) 215-223 Oct 2004 [Refereed]
Nishino, J, Yamashita, K, Hashiguchi, H, Fujii, H, Shimazaki, T, Hamada, H
EMBO JOURNAL 23(9) 1998-2008 May 2004 [Refereed]
Okada, S, Nakamura, M, Mikami, Y, Shimazaki, T, Mihara, M, Ohsugi, Y, Iwamoto, Y, Yoshizaki, K, Kishimoto, T, Toyama, Y, Okano, H
JOURNAL OF NEUROSCIENCE RESEARCH 76(2) 265-276 Apr 2004 [Refereed]
ES細胞と神経幹細胞の分化
島崎琢也
CLINICAL NYUROSCIENCE 22(3) 281-283 Mar 2004
Isolation and transplantation of dopaminergic neurons generated from mouse embryonic stem cells.
'Yoshizaki T, Inaji M, Kouike H, Shimazaki T, Sawamoto K, Ando K, Date I, Kobayashi K, Suhara T, Uchiyama Y, Okano H'
Neurosci. Lett. 363 33-37 2004 [Refereed]
Implantation of dendritic cells in injured adult spinal cord results in activation of endogenous neural stem/progenitor cells leading to de novo neurogenesis and functional recovery.
'Mikami Y, Okano H, Sakaguchi M, Nakamura M, Shimazaki T, Okano HJ, Kawakami Y, Toyama Y, Toda M.'
J. Neurosci. Res. 76 453-465 2004 [Refereed]
Downregulation of STAT3 activation is required for presumptive rod photoreceptor cells to differentiate in the postnatal retina.
'Ozawa Y, Nakao K, Shimazaki T, Takeda J, Akira S, Ishihara K, Hirano T, Oguchi Y, Okano H.'
Mol. Cell. Neurosci. 26 258-270 2004 [Refereed]
Kokuzawa, J, Yoshimura, S, Kitajima, H, Shinoda, J, Kaku, Y, Iwama, T, Morishita, R, Shimazaki, T, Okano, H, Kunisada, T, Sakai, N
MOLECULAR AND CELLULAR NEUROSCIENCE 24(1) 190-197 Sep 2003 [Refereed]
ES細胞からの運動神経前駆細胞の分化誘導
島崎琢也
脳21 6(2) 137-143 Apr 2003
Glycoprotein 130 signaling regulates Notch1 expression and activation in the self-renewal of mammalian forebrain neural stem cells
Chojnacki, A, Shimazaki, T, Gregg, C, Weinmaster, G, Weiss, S
JOURNAL OF NEUROSCIENCE 23(5) 1730-1741 Mar 2003 [Refereed]
ヒト神経幹細胞移植
Shimazaki Takuya, Okano Hideyuki
神経研究の進歩 46(6) 790-797 Dec 2002
Murayama, A, Matsuzaki, Y, Kawaguchi, A, Shimazaki, T, Okano, H
JOURNAL OF NEUROSCIENCE RESEARCH 69(6) 837-847 Sep 2002 [Refereed]
サイトカインによる神経幹細胞の長期維持機構
Shimazaki Takuya
神経研究の進歩 46(2) 211-219 Apr 2002
Erythropoietin regulates the in vitro and in vivo production of neuronal progenitors by mammalian forebrain neural stem cells
Shingo Tetsuro, Sorokan Todd S, Shimazaki Takuya, Weiss Samuel
Journal of Neuroscience 21(24) 9733-9743 Dec 2001 [Refereed]
Brain from bone: Efficient "meta-differentiation" of marrow stroma-derived mature osteoblasts to neurons with Noggin or a demethylating agent
Kohyama, J, Abe, H, Shimazaki, T, Koizumi, A, Nakashima, K, Gojo, S, Taga, T, Okano, H, Hata, J, Umezawa, A
DIFFERENTIATION 68(4-5) 235-244 Oct 2001 [Refereed]
The ciliary neurotrophic factor/leukemia inhibitory factor/gp130 receptor complex operates in the maintenance of mammalian forebrain neural stem cells
Shimazaki Takuya, Shingo Tetsuro, Weiss Samuel
Journal of Neuroscience 21(19) 7642-7653 Oct 2001 [Refereed]
EGF-responsive neural stem cells are a transient population in the developing mouse spinal cord
Represa, A, Shimazaki, T, Simmonds, M, Weiss, S
EUROPEAN JOURNAL OF NEUROSCIENCE 14(3) 452-462 Aug 2001 [Refereed]
The bHLH gene Hes1 as a repressor of the neuronal commitment of CNS stem cells
Nakamura, Y, Sakakibara, S, Miyata, T, Ogawa, M, Shimazaki, T, Weiss, S, Kageyama, R, Okano, H
JOURNAL OF NEUROSCIENCE 20(1) 283-293 Jan 2000 [Refereed]
GFR alpha 3, a component of the artemin receptor, is required for migration and survival of the superior cervical ganglion
Nishino, J, Mochida, K, Ohfuji, Y, Shimazaki, T, Meno, C, Ohishi, S, Matsuda, Y, Fujii, H, Saijoh, Y, Hamada, H
NEURON 23(4) 725-736 Aug 1999 [Refereed]
A role for the POU-III transcription factor Brn-4 in the regulation of striatal neuron precursor differentiation
Shimazaki, T, Arsenijevic, Y, Ryan, AK, Rosenfeld, MG, Weiss, S
EMBO JOURNAL 18(2) 444-456 Jan 1999 [Refereed]
HYBRID CELL EXTINCTION AND REEXPRESSION OF OCT-3 FUNCTION CORRELATES WITH DIFFERENTIATION POTENTIAL
SHIMAZAKI, T, OKAZAWA, H, FUJII, H, IKEDA, M, TAMAI, K, MCKAY, RDG, MURAMATSU, M, HAMADA, H
EMBO JOURNAL 12(12) 4489-4498 Dec 1993 [Refereed]
MURINE CHROMOSOMAL LOCATION OF 4 CLASS-III POU TRANSCRIPTION FACTORS
AVRAHAM, KB, CHO, BC, GILBERT, D, FUJII, H, OKAMOTO, K, SHIMAZAKI, T, ITO, T, SHOJI, H, WAKAMATSU, Y, KONDOH, H, TAKAHASHI, N, MURAMATSU, M, HAMADA, H, COPELAND, NG, JENKINS, NA
GENOMICS 18(1) 131-133 Oct 1993 [Refereed]
Misc
Shimazaki, T
HORMONE RESEARCH 60 1-9 2003
Isolation and transplantation of dopaminergic neurons and neural stem cells
Okano, H, Yoshizaki, T, Shimazaki, T, Sawamoto, K
PARKINSONISM & RELATED DISORDERS 9(1) 23-28 Oct 2002 [Refereed]
Conference Activities & Talks
神経幹細胞の分化に及ぼす外傷性脳損傷後の炎症性サイトカインの影響
'並木淳, 島崎琢也, 鈴木さゆり, 岡野栄之'
第27回日本神経外傷学会 Mar 2004
骨髄由来の神経幹細胞選択的nestin遺伝子発現細胞
'並木淳, 島崎琢也, 松崎有未, 鈴木さゆり, 岡野栄之'
第3回日本再生医療学会総会 Mar 2004
ES細胞を利用した神経再生の可能性 [Invited]
'島崎琢也, 岡野栄之'
第3回日本再生医療学会総会・シンポジウム Mar 2004
比較ゲノム情報学を用いたIslet-1遺伝子の神経細胞サブタイプ特異的発現機構の解明
'植村修, 岡田洋平, 安藤秀樹, Guedj Mikael, 東島眞一, 島崎琢也, 千野直一, 岡野栄之, 岡本仁'
第26回日本分子生物学会年会 Dec 2003
Downregulation of STAT3 activation contiributes to triggering the differentiation of presumptive rod photoreceptor cells
'Ozawa Yoko, Nakao Keiko, Shimazaki Takuya, Takeda Junji, Akira Shizuo, Ishihara Katsuhiko, Hirano Toshio, Okano Hideyuki'
第26回日本分子生物学会年会 Dec 2003
Research Grants & Projects
Transcription factors regulating temporal specification of neuronal subtypes.
MEXT,JSPS: Grant-in-Aid for Scientific Research
Project Year: Apr 2019 - Mar 2021 Investigator(s): 島崎 琢也
Regulatory mechanisms of aging of adult neural stem/progenitor cells via p38 MAPK
MEXT,JSPS: Grant-in-Aid for Scientific Research
Project Year: Apr 2018 - Mar 2021 Investigator(s): 島崎 琢也
Mechanisms of glial development
MEXT,JSPS: Grant-in-Aid for Scientific Research
Project Year: Apr 2015 - Mar 2018 Investigator(s): 島崎 琢也
