Tatsushi Yokoyama

Profile Information

Affiliation: Program-Specific Researcher, Institute for Life and Medical Sciences, Kyoto University

Degree: M.D.(Mar, 2014, The University of Tokyo)
Ph.D.(Mar, 2020, The University of Tokyo)

Researcher number: 30892260
ORCID ID: https://orcid.org/0000-0001-7159-9039
J-GLOBAL ID: 201901012529469652
researchmap Member ID: B000361931

Research Areas

Research History

Sep, 2024 - Present

Program-Specific Assistant Professor, Institute for Life and Medical Sciences, Kyoto University
Jul, 2024 - Aug, 2024

Program-Specific Researcher, Institute for Life and Medical Sciences, Kyoto University
Jul, 2020 - Jun, 2024

psychiatrist, psychiatry, Daigo Hospital
Jul, 2020 - Jun, 2024

Postdoctoral fellow, Graduate School of Biostudies, Kyoto University
Apr, 2020 - Jun, 2020

Postdoctoral fellow, Department of Neurochemistry, Graduate School of Medicine, The University of Tokyo
Apr, 2018 - Mar, 2020

Research Fellow (DC2), Japan Society for the Promotion of Science (JSPS)
Apr, 2014 - Mar, 2016

Junior Resident, Postgraduate Clinical Training Program, The University of Tokyo Hospital

Education

Apr, 2016 - Mar, 2020

Graduate Program for Leaders in Life Innovation (GPLLI) / World-leading Innovative Graduate Study Program for Life Science and Technology (WINGS-LST), The University of Tokyo
Apr, 2016 - Mar, 2020

Ph.D. Course under supervision of Dr. Haruhiko Bito, Department of Neurochemistry, Graduate School of Medicine, The University of Tokyo
Apr, 2008 - Mar, 2014

Faculty of Medicine, The University of Tokyo

Awards

Mar, 2013

Otsubo Osamu Tetsumon Fellowship

Tatsushi Yokoyama

Papers

The A-kinase anchoring protein Yotiao decrease the ER calcium content by inhibiting the store operated calcium entry

Liuqing Wang, Jiaxuan Zhang, Wanjie Li, Xiaoyan Zhang, Tatsushi Yokoyama, Masayuki Sakamoto, Youjun Wang

Cell Calcium, 121 102906-102906, Jul, 2024 Peer-reviewed
Probing neuronal activity with genetically encoded calcium and voltage fluorescent indicators.

Masayuki Sakamoto, Tatsushi Yokoyama

Neuroscience research, Jun 15, 2024 Peer-reviewedInvited
A multicolor suite for deciphering population coding of calcium and cAMP in vivo

Tatsushi Yokoyama, Satoshi Manita, Hiroyuki Uwamori, Mio Tajiri, Itaru Imayoshi, Sho Yagishita, Masanori Murayama, Kazuo Kitamura, Masayuki Sakamoto

Nature Methods, Mar 21, 2024 Peer-reviewedLead authorCorresponding author
Genome-wide CRISPR screen identifies AC9 as a key regulator of ER Ca²⁺homeostasis involved in neuronal differentiation

Liuqing Wang, Jia Li, Yiping Wang, Ziyi Zhong, Yuqing Wang, Rui Huang, Bingwei Zhang, Panpan Liu, Erkejiang Ye, Ruotong Cao …

bioRxiv, Feb 6, 2024
A multicolor suite for deciphering population coding in calcium and cAMPin vivo

Tatsushi Yokoyama, Satoshi Manita, Hiroyuki Uwamori, Mio Tajiri, Itaru Imayoshi, Sho Yagishita, Masanori Murayama, Kazuo Kitamura, Masayuki Sakamoto

bioRxiv, Jan 8, 2023 Lead authorCorresponding author
A Flp-dependent G-CaMP9a transgenic mouse for neuronal imaging in vivo.

Masayuki Sakamoto, Masatoshi Inoue, Atsuya Takeuchi, Shigetaka Kobari, Tatsushi Yokoyama, Shin-Ichiro Horigane, Sayaka Takemoto-Kimura, Manabu Abe, Kenji Sakimura, Masanobu Kano …

Cell reports methods, 2(2) 100168-100168, Feb 28, 2022 Peer-reviewed
Imaging Voltage with Microbial Rhodopsins

Xiao Min Zhang, Tatsushi Yokoyama, Masayuki Sakamoto

Frontiers in Molecular Biosciences, 8, Aug 25, 2021 Peer-reviewed
A Photodeactivatable Antagonist for Controlling CREB-Dependent Gene Expression

Takuma Imoto, Masafumi Minoshima, Tatsushi Yokoyama, Ben P. Emery, Steven D. Bull, Haruhiko Bito, Kazuya Kikuchi

ACS Central Science, 6(10) 1813-1818, Oct 28, 2020 Peer-reviewed
Photolytic Release of a Caged Inhibitor of an Endogenous Transcription Factor Enables Optochemical Control of CREB-Mediated Gene Expression.

Takuma Imoto, Akihiro Kawase, Masafumi Minoshima, Tatsushi Yokoyama, Haruhiko Bito, Kazuya Kikuchi

Organic letters, 22(1) 22-25, Jan 3, 2020 Peer-reviewed
Rational Engineering of XCaMPs, a Multicolor GECI Suite for In Vivo Imaging of Complex Brain Circuit Dynamics.

Masatoshi Inoue, Atsuya Takeuchi, Satoshi Manita, Shin-Ichiro Horigane, Masayuki Sakamoto, Ryosuke Kawakami, Kazushi Yamaguchi, Kouhei Otomo, Hiroyuki Yokoyama, Ryang Kim …

Cell, 177(5) 1346-1360, May 16, 2019 Peer-reviewed
A case of recurrent depressive disorder presenting with Alice in Wonderland syndrome: psychopathology and pre- and post-treatment FDG-PET findings.

Tatsushi Yokoyama, Tsuyoshi Okamura, Miwako Takahashi, Toshimitsu Momose, Shinsuke Kondo

BMC psychiatry, 17(1) 150-150, Apr 27, 2017 Peer-reviewedLead author

Misc.

Ca2＋とcAMPの同時in vivo 2光子イメージング

横山達士, 坂本雅行

実験医学, 42(14) 2211, Sep, 2024

Presentations

Deciphering population coding in calcium and cAMP in vivo

The 46th annual meeting of the japan neuroscience society, Aug 3, 2023
Development and application of a supersensitive indicator for cAMP

Tatsushi Yokoyama

NEURO2022, Jun 30, 2022
In vivo CREB imaging using an intensiometric indicator

Tatsushi Yokoyama

UK-Japan Neuroscience Symposium, Feb 4, 2020
An intensiometric, genetically encoded, indicator for imaging CREB phosphorylation in vivo

Tatsushi Yokoyama

NEURO2019, Jul 29, 2019

Professional Memberships

Research Projects

線条体における神経伝達物質と細胞内シグナルの間の計算原理解明

科学研究費助成事業, 若手研究, 日本学術振興会, Apr, 2024 - Mar, 2027

横山達士
タンパク工学を基点としたオーファン GPCR の機能解明

ACT-X「生命と化学」加速フェーズ, 科学技術振興機構(JST), Apr, 2024 - Mar, 2025
タンパク工学を基点としたオーファン GPCR の機能解明

ACT-X「生命と化学」, 科学技術振興機構(JST), Oct, 2021 - Mar, 2024
線条体の神経活動を制御する入力の時間枠と空間枠

科学研究費助成事業若手研究, 若手研究, 日本学術振興会, Apr, 2021 - Mar, 2024

横山達士
転写因子ＣＲＥＢ活性のｉｎｖｉｖｏ動態可視化による、長期記憶形成の機序解明

科学研究費助成事業特別研究員奨励費, 特別研究員奨励費, 日本学術振興会, Apr, 2018 - Mar, 2020

横山達士

Other

USMLE STEP1

Sep, 2012 - Sep, 2012

Passed USMLE（United States Medical Licensing Examination）STEP1
A designated psychiatrist

Profile Information

Research Areas

Research History

Education

Awards

Papers

Misc.

Presentations

Professional Memberships

Research Projects

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