細田徹 (Toru Hosoda) - マイポータル

基本情報

所属: 榊原記念病院総合診療部部長

学位: 医学博士(東京大学)

ORCID iD: https://orcid.org/0000-0002-7273-0630
J-GLOBAL ID: 201501014861613990
Researcher ID: G-1873-2010
researchmap会員ID: B000247560

外部リンク: https://kaken.nii.ac.jp/d/r/50608601.ja.html

研究キーワード

研究分野

ライフサイエンス / 循環器内科学 /

経歴

2011年 - 2013年

東海大学, 准教授

論文

Single-cell analysis of the fate of c-kit-positive bone marrow cells

Anna Czarna, Fumihiro Sanada, Alex Matsuda, Junghyun Kim, Sergio Signore, João D. Pereira, Andrea Sorrentino, Ramaswamy Kannappan, Antonio Cannatà, Toru Hosoda …

npj Regenerative Medicine 2(1) 2017年12月1日
Cardiovascular Stem Cell Niche

Annarosa Leri, Marcello Rota, Polina Goichberg, Toru Hosoda, Tiziano Moccetti, Piero Anversa

Biology and Engineering of Stem Cell Niches 93-109 2017年4月14日査読有り
The proliferative potential of human cardiac stem cells was unaffected after a long-term cryopreservation of tissue blocks.

Toru Hosoda, Nobuo Iguchi, Yasunori Cho, Masaki Inoue, Tsutomu Murakami, Minoru Tabata, Shuichiro Takanashi, Hitonobu Tomoike

Annals of translational medicine 5(3) 41-41 2017年2月
How do resident stem cells repair the damaged myocardium?

Emiko Hayashi, Toru Hosoda

WORLD JOURNAL OF STEM CELLS 7(1) 182-185 2015年1月査読有り
Myocyte renewal and therapeutic myocardial regeneration using various progenitor cells

Emiko Hayashi, Toru Hosoda

HEART FAILURE REVIEWS 19(6) 789-797 2014年11月査読有り
Cardiac stem cell niches

Annarosa Leri, Marcello Rota, Toru Hosoda, Polina Goichberg, Piero Anversa

STEM CELL RESEARCH 13(3) 631-646 2014年11月査読有り
Response to Letter Regarding Article "Inositol 1,4,5-Trisphosphate Receptors and Human Left Ventricular Myocytes"

Sergio Signore, Andrea Sorrentino, Joao Ferreira-Martins, Ramaswamy Kannappan, Mehrdad Shafaie, Fabio Del Ben, Kazuya Isobe, Christian Arranto, Ewa Wybieralska, Andrew Webster …

CIRCULATION 129(21) E510-E511 2014年5月査読有り
GDF11 enhances proliferation of human cardiac stem cells

Hosoda, T., Hayashi, E., Iguchi, N., Takanashi, S., Tomoike, H.

European Heart Journal 35 112-112 2014年
c-Kit-Positive Cardiac Stem Cells Nested in Hypoxic Niches Are Activated by Stem Cell Factor Reversing the Aging Myopathy

Fumihiro Sanada, Junghyun Kim, Anna Czarna, Noel Yan-Ki Chan, Sergio Signore, Barbara Ogorek, Kazuya Isobe, Ewa Wybieralska, Giulia Borghetti, Ada Pesapane …

CIRCULATION RESEARCH 114(1) 41-55 2014年1月査読有り
Inositol 1, 4, 5-Trisphosphate Receptors and Human Left Ventricular Myocytes

Sergio Signore, Andrea Sorrentino, Joao Ferreira-Martins, Ramaswamy Kannappan, Mehrdad Shafaie, Fabio Del Ben, Kazuya Isobe, Christian Arranto, Ewa Wybieralska, Andrew Webster …

CIRCULATION 128(12) 1286-1297 2013年9月査読有り
Dissecting the Molecular Relationship Among Various Cardiogenic Progenitor Cells

Devaveena Dey, Leng Han, Michael Bauer, Fumihiro Sanada, Angelos Oikonomopoulos, Toru Hosoda, Kazumasa Unno, Patricia De Almeida, Annarosa Leri, Joseph C. Wu

CIRCULATION RESEARCH 112(9) 1253-U175 2013年4月査読有り
Hypoxic and Normoxic Niches Regulate Cardiac Stem Cell Function

Sanada, Fumihiro, Kim, Junghyung, Czarna, Anna, Chan, Noel Y., Signore, Sargio, Isobe, Kazuya, Sorrentino, Andrea, Mangiaracina, Chiara, Wybieralska, Ewa, Cimini, Maria …

Circulation Research 113(4) 2013年
Therapeutic application of cardiac stem cells and other cell types

Emiko Hayashi, Toru Hosoda

BioMed Research International 2013 736815 2013年査読有り
The mircrine mechanism controlling cardiac stem cell fate

Toru Hosoda

Frontiers in Genetics 4 204 2013年査読有り
Cardiomyogenesis in the Aging and Failing Human Heart

Jan Kajstura, Marcello Rota, Donato Cappetta, Barbara Ogorek, Christian Arranto, Yingnan Bai, Joao Ferreira-Martins, Sergio Signore, Fumihiro Sanada, Alex Matsuda …

CIRCULATION 126(15) 1869-U238 2012年10月査読有り
Tracking Chromatid Segregation to Identify Human Cardiac Stem Cells That Regenerate Extensively the Infarcted Myocardium

Jan Kajstura, Yingnan Bai, Donato Cappetta, Junghyun Kim, Christian Arranto, Fumihiro Sanada, Domenico D'Amario, Alex Matsuda, Silvana Bardelli, Joao Ferreira-Martins …

CIRCULATION RESEARCH 111(7) 894-+ 2012年9月査読有り
Cardiomyogenesis in the Developing Heart Is Regulated by C-Kit-Positive Cardiac Stem Cells

Joao Ferreira-Martins, Barbara Ogorek, Donato Cappetta, Alex Matsuda, Sergio Signore, Domenico D'Amario, James Kostyla, Elisabeth Steadman, Noriko Ide-Iwata, Fumihiro Sanada …

CIRCULATION RESEARCH 110(5) 701-U171 2012年3月査読有り
Response to Bergmann et al: Carbon 14 Birth Dating of Human Cardiomyocytes

Jan Kajstura, Marcello Rota, Toru Hosoda, Piero Anversa, Annarosa Leri

CIRCULATION RESEARCH 110(1) E19-E21 2012年1月査読有り
C-kit-positive cardiac stem cells and myocardial regeneration.

Hosoda T

American journal of cardiovascular disease 2(1) 58-67 2012年査読有り
Cardiac stem cells in patients with ischaemic cardiomyopathy (SCIPIO): initial results of a randomised phase 1 trial

Roberto Bolli, Atul R. Chugh, Domenico D'Amario, John H. Loughran, Marcus F. Stoddard, Sohail Ikram, Garth M. Beache, Stephen G. Wagner, Annarosa Leri, Toru Hosoda …

LANCET 378(9806) 1847-1857 2011年11月査読有り

もっとみる

MISC

100

Single-Cell Analysis of the Fate of c-kit-Positive Bone Marrow Cells

Anna Czarna, Fumihiro Sanada, Alex Matsuda, Junghyun Kim, Sergio Signore, Andrea Sorrentino, Ramaswamy Kannappan, Toru Hosoda, Tiziano Moccetti, Piero Anversa …

CIRCULATION RESEARCH 119(12) E169-E169 2016年12月
Retrospective C-14 Birth Dating of Human Cardiomyocytes

Alex Matsuda, Anna Czarna, Junghyun Kim, Marco Moccetti, Toru Hosoda, Marcello Rota, Annarosa Leri, Tiziano Moccetti, Piero Anversa

CIRCULATION RESEARCH 119(12) E171-E171 2016年12月
Fate Mapping of c-kit-Positive Pancreatic Cells

Alex Matsuda, Barbara Ogorek, Laura Graciotti, Xiaoli Liu, Konstantinos E. Hatzistergos, Ewa Wybieralska, Junghyun Kim, Dieter Saur, Barbara Seidler, Toru Hosoda …

CIRCULATION 134 2016年11月
Adult Stem Cells in Tissue Maintenance and Regeneration

Stefania Montagnani, Maria A. Rueger, Toru Hosoda, Daria Nurzynska

STEM CELLS INTERNATIONAL 2016年
Fate Mapping of Bone Marrow Cell Transdifferentiation In Vivo

Anna Czarna, Fumihiro Sanada, Toru Hosoda, Sergio Signore, Piero Anversa, Marcello Rota, Annarosa Leri

CIRCULATION RESEARCH 115(12) E93-E93 2014年12月
Migration of MicroRNAs From Cardiomyocytes to Cancer Cells Interferes With Tumor Formation in the Adult Heart

Laura Graciotti, Toru Hosoda, Fumihiro Sanada, Giulia Borghetti, Christian Arranto, Fiorenza Valeriani, Ewa Wybieralska, Barbara Ogorek, Marcello Rota, Poling Goichberg …

CIRCULATION 130 2014年11月
Transfer of MicroRNAs From Cardiomyocytes Prevents the Growth of Cancer Cells

Laura Graciotti, Toru Hosoda, Fumihiro Sanada, Giulia Borghetti, Christian Arranto, Ramaswamy Kannappan, Silvana Bardelli, Marco Moccetti, Marcello Rota, Poling Goichberg …

CIRCULATION 130 2014年11月
Cardiomyocytes Inhibit the Growth of Lung and Breast Cancer Cells but Fail to Abrogate the Proliferation of Melanoma Cells

Laura Graciotti, Toru Hosoda, Fumihiro Sanada, Giulia Borghetti, Christian Arranto, Fiorenza Valeriani, Ewa Wybieralska, Barbara Ogorek, Marcello Rota, Polina Goichberg …

CIRCULATION 130 2014年11月
Cardiomyogenesis in the aging and failing human heart (vol 126, pg 1869, 2012)

Jan Kajstura, Marcello Rota, Donato Cappetta, Barbara Ogorek, Christian Arranto, Yingnan Bai, Joao Ferreira-Martins, Sergio Signore, Fumihiro Sanada, Alex Matsuda …

CIRCULATION 129(16) E466-E466 2014年4月
Clonal C-kit-Positive Bone Marrow Cells and Cardiomyogenesis

Fumihiro Sanada, Junghyun Kim, Anna Czarna, Sergio Signore, Andrea Sorrentino, Chiara Mangiaracina, Ramaswamy Kannappan, Polina Goihberg, Marcello Rota, Toru Hosoda …

CIRCULATION 128(22) 2013年11月
Transdifferentiation of Bone Marrow Cells and Cardiomyogenesis in the Infarcted Heart

Fumihiro Sanada, Junghyun Kim, Anna Czarna, Sergi Signore, Andrea Sorrentino, Chiara Mangiaracina, Antonio Cannata, Kazuya Isobe, Ramaswamy Kannappan, Maria Cimini …

CIRCULATION 128(22) 2013年11月
Genetic Deletion of Telomerase Promotes Premature Cardiac Aging

Junghyun Kim, Fumihiro Sanada, Manila Candiracci, Fiorenza Valeriani, Anna Czarna, Antonio Cannata, Polina Goihberg, Toru Hosoda, Jan Kajstura, Marcello Rota …

CIRCULATION 128(22) 2013年11月
Bone Marrow Cells Form New Cardiomyocytes in the Infarcted Myocardium

Fumihiro Sanada, Junghyung Kim, Anna Czarna, Sergio Signore, Andrea Sorrentino, Chiara Mangiaracina, Ramaswamy Kannappan, Kazuya Isobe, Polina Goichberg, Marcello Rota …

CIRCULATION RESEARCH 113(4) 2013年8月
Functional Properties of Cardiac Stem Cell Niches in the Young and Old Heart

Junghyun Kim, Hanqiao Zheng, Donato Cappetta, Fumihiro Sanada, Christian Arranto, Narasimman Gurusamy, Polina Goichberg, Toru Hosoda, Marcello Rota, Jan Kajstura …

CIRCULATION RESEARCH 113(4) 2013年8月
Genetic Deletion Of Telomerase Promotes Premature Cardiac Aging

Junghyun Kim, Fumihiro Sanada, Maria Cimini, Polina Goihberg, Toru Hosoda, Marcello Rota, Jan Kajstura, Piero Anversa, Annarosa Leri

CIRCULATION RESEARCH 113(4) 2013年8月
Effect of Cardiac Stem Cells in Patients With Ischemic Cardiomyopathy: Interim Results of the SCIPIO Trial Up to 2 Years After Therapy

Roberto Bolli, Atul Chugh, Domenico D'Amario, John H. Loughran, Marcus F. Stoddard, Sohail Ikram, Stephen G. Wagner, Garth M. Beache, Annarosa Leri, Toru Hosoda …

CIRCULATION 126(23) 2784-2784 2012年12月
Telomeric Shortening Induces a Senescent Cardiomyopathy that is Independent from Chronological age

Junghyun Kim, Fumihiro Sanada, Maria Cimini, Christian Arranto, Polina Goihberg, Toru Hosoda, Marcello Rota, Jan Kajstura, Piero Anversa, Annarosa Leri

CIRCULATION RESEARCH 111(12) E381-E381 2012年12月
Carbon 14 Retrospective Birth Dating Reveals Distinct Rates of Proliferation of Cardiac Cells

Maria-Virginia Caballero, Ewa Wybieralska, Marcello Rota, Donato Cappetta, Barbara Ogorek, Christian Arranto, Yingnan Bai, Sergio Signore, Fumihiro Sanada, Alex Matsuda …

CIRCULATION 126(21) 2012年11月
Clonal Analysis of Hematopoietic Stem Cell Transdifferentiation in the Regenerated Myocardium

Fumihiro Sanada, Kim Junghyun, Sergio Sinore, Kazuya Isobe, Joao Ferreira-Martins, Christian Arranto, Ramaswamy Kannapan, Maria Cimini, Alex Matsuda, Donato Cappetta …

CIRCULATION 126(21) 2012年11月
The Histone Methyltransferase Smyd3 Modulates Growth and Differentiation of Human Cardiac Stem Cells

Narasimman Gurusamy, Junghyun Kim, Toru Hosoda, Claudia Fiorini, Fumihiro Sanada, Virginia Caballero, Domenico D'Amario, Hanqiao Zheng, Marcello Rota, Federica del Monte …

CIRCULATION 126(21) 2012年11月

もっとみる

共同研究・競争的資金等の研究課題

ヒト心臓幹細胞からの心筋分化誘導法の樹立～心疾患テーラーメイド医療へのシナリオ～

日本学術振興会科学研究費助成事業基盤研究(C) 2013年4月 - 2016年3月

細田徹, 友池仁暢, 井口信雄, 高梨秀一郎
c-kit陽性ヒト心臓幹細胞(CSC)の単離と培養:日本初の臨床試験実施へ向けて

日本学術振興会科学研究費助成事業研究活動スタート支援 2011年 - 2012年

細田徹

細田徹

基本情報

研究キーワード

研究分野

経歴

論文

MISC

共同研究・競争的資金等の研究課題

メニュー

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