Wei-Chieh Chiang (Chiang Wei-Chieh) - マイポータル

基本情報

所属: 沖縄科学技術大学院大学

学位: Ph.D.(University of California, San Diego)

通称等の別名: Jerry Chiang
J-GLOBAL ID: 202001004723172421
researchmap会員ID: B000381591

研究キーワード

研究分野

経歴

2019年 - 現在

Okinawa Institute of Science and Technology Graduate University, Developmental Neurobiology Unit, Staff Scientist
2018年 - 2019年

University of California, San Diego, Pathology, Associate Project Scientist
2014年 - 2018年

VA San Diego Health Care System, Research Biologist
2008年 - 2014年

University of California, San Diego, Pathology, Postdoctoral Research Fellow

学歴

- 2008年

University of California, San Diego, Chemistry and Biochemistry, Ph.D.
- 2007年

San Diego State University, Chemistry, M.A.
- 2001年

National Taiwan University, Chemistry, B.S.

受賞

2019年

ARVO 2019 Travel Award, The Association for Research in Vision and Ophthalmology

Chiang Wei-Chieh
2018年

American Society for Investigative Pathology Trainee Travel Award, American Society for Investigative Pathology

Chiang Wei-Chieh
2018年

BrightFocus Foundation Travel Award, BrightFocus Foundation Travel Award for XVIIIth International Symposium on Retinal Degenerations

Chiang Wei-Chieh
2014年

NEI Travel Award for XVIth International Symposium on Retinal Degenerations

Chiang Wei-Chieh
2014年

American Society for Investigative Pathology A. D. Sobel - ASIP Education Fund Scholar Awards, American Society for Investigative Pathology

Chiang Wei-Chieh
2010年

American Society for Investigative Pathology Young Pathologist Fellowship

Chiang Wei-Chieh
2009年

Fight-For-Sight Postdoctoral Fellowship, Unfolded Protein Response Signaling in Rhodopsin Protein Processing and Stability, Fight-For-Sight

Chiang Wei-Chieh
2005年

Arne N. Wick Predoctoral Research Fellowship, California Metabolic Research Foundation

Chiang Wei-Chieh
2003年

Research fellowship of Shared Visions Fund, Graduate Division at San Diego State University

Chiang Wei-Chieh

論文

The unfolded protein response regulator ATF6 promotes mesodermal differentiation.

Kroeger H, Grimsey N, Paxman R, Chiang WC, Plate L, Jones Y, Shaw PX, Trejo J, Tsang SH, Powers E …

Science signaling 11(517) 2018年2月査読有り
ER stress and unfolded protein response in ocular health and disease

Kroeger H, Chiang WC, Felden J, Nguyen A, Lin JH

The FEBS journal 286(2) 399-412 2018年査読有り
Autosomal recessive cone-rod dystrophy can be caused by mutations in the ATF6 gene

Anna Skorczyk-Werner, Wei-Chieh Chiang, Anna Wawrocka, Katarzyna Wicher, Malgorzata Jarmuz-Szymczak, Magdalena Kostrzewska-Poczekaj, Aleksander Jamsheer, Rafal Ploski, Malgorzata Rydzanicz, Dorota Pojda-Wilczek …

EUROPEAN JOURNAL OF HUMAN GENETICS 25(11) 1210-1216 2017年11月査読有り
Achromatopsia mutations target sequential steps of ATF6 activation

Wei-Chieh Chiang, Priscilla Chan, Bernd Wissinger, Ajoy Vincent, Anna Skorczyk-Werner, Maciej R. Krawczynski, Randal J. Kaufman, Stephen H. Tsang, Elise Heon, Susanne Kohl …

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 114(2) 400-405 2017年1月査読有り
Endoplasmic reticulum stress in human photoreceptor diseases

Priscilla Chan, Julia Stolz, Susanne Kohl, Wei-Chieh Chiang, Jonathan H. Lin

BRAIN RESEARCH 1648(Pt B) 538-541 2016年10月査読有り
Ablation of Chop Transiently Enhances Photoreceptor Survival but Does Not Prevent Retinal Degeneration in Transgenic Mice Expressing Human P23H Rhodopsin

Wei-Chieh Chiang, Victory Joseph, Douglas Yasumura, Michael T. Matthes, Alfred S. Lewin, Marina S. Gorbatyuk, Kelly Ahern, Matthew M. LaVail, Jonathan H. Lin

RETINAL DEGENERATIVE DISEASES: MECHANISMS AND EXPERIMENTAL THERAPY 854 185-191 2016年査読有り
In Vivo Visualization of Endoplasmic Reticulum Stress in the Retina Using the ERAI Reporter Mouse

Marcel V. Alavi, Wei-Chieh Chiang, Heike Kroeger, Douglas Yasumura, Michael T. Matthes, Takao Iwawaki, Matthew M. LaVail, Douglas B. Gould, Jonathan H. Lin

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 56(11) 6961-6970 2015年10月査読有り
Robust Endoplasmic Reticulum-Associated Degradation of Rhodopsin Precedes Retinal Degeneration

Wei-Chieh Chiang, Heike Kroeger, Sanae Sakami, Carissa Messah, Douglas Yasumura, Michael T. Matthes, Judith A. Coppinger, Krzysztof Palczewski, Matthew M. LaVail, Jonathan H. Lin

MOLECULAR NEUROBIOLOGY 52(1) 679-695 2015年8月査読有り
Mutations in the unfolded protein response regulator ATF6 cause the cone dysfunction disorder achromatopsia

Susanne Kohl, Ditta Zobor, Wei-Chieh Chiang, Nicole Weisschuh, Jennifer Staller, Irene Gonzalez Menendez, Stanley Chang, Susanne C. Beck, Marina Garcia Garrido, Vithiyanjali Sothilingam …

NATURE GENETICS 47(7) 757-+ 2015年7月査読有り
Multiple Mechanisms of Unfolded Protein Response–Induced Cell Death

Hiramatsu N, Chiang WC, Kurt TD, Sigurdson CJ, Lin JH

The American journal of pathology 185(7) 1800-1808 2015年7月査読有り
De Novo Prion Aggregates Trigger Autophagy in Skeletal Muscle

Shivanjali Joshi-Barr, Cyrus Bett, Wei-Chieh Chiang, Margarita Trejo, Hans H. Goebel, Beata Sikorska, Pawel Liberski, Alex Raeber, Jonathan H. Lin, Eliezer Masliah …

JOURNAL OF VIROLOGY 88(4) 2071-2082 2014年2月査読有り
The Effects of IRE1, ATF6, and PERK Signaling on adRP-Linked Rhodopsins

Wei-Chieh Jerry Chiang, Jonathan H. Lin

RETINAL DEGENERATIVE DISEASES: MECHANISMS AND EXPERIMENTAL THERAPY 801 661-667 2014年査読有り
Induction of Endoplasmic Reticulum Stress Genes, BiP and Chop, in Genetic and Environmental Models of Retinal Degeneration

Heike Kroeger, Carissa Messah, Kelly Ahern, Jason Gee, Victory Joseph, Michael T. Matthes, Douglas Yasumura, Marina S. Gorbatyuk, Wei-Chieh Chiang, Matthew M. LaVail …

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 53(12) 7590-7599 2012年11月査読有り
Selective Activation of ATF6 and PERK Endoplasmic Reticulum Stress Signaling Pathways Prevent Mutant Rhodopsin Accumulation

Wei-Chieh Chiang, Nobuhiko Hiramatsu, Carissa Messah, Heike Kroeger, Jonathan H. Lin

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 53(11) 7159-7166 2012年10月査読有り
IRE1 directs proteasomal and lysosomal degradation of misfolded rhodopsin

Wei-Chieh Chiang, Carissa Messah, Jonathan H. Lin

MOLECULAR BIOLOGY OF THE CELL 23(5) 758-770 2012年3月査読有り
Endoplasmic Reticulum-Associated Degradation (ERAD) of Misfolded Glycoproteins and Mutant P23H Rhodopsin in Photoreceptor Cells

Heike Kroeger, Wei-Chieh Chiang, Jonathan H. Lin

RETINAL DEGENERATIVE DISEASES 723 559-565 2012年査読有り
Inhibition of human NTPDase 2 by modification of an intramembrane cysteine by p-chloromercuriphenylsulfonate and oxidative cross-linking of the transmembrane domains

Wei-Chieh Chiang, Aileen F. Knowles

BIOCHEMISTRY 47(33) 8775-8785 2008年8月査読有り
Transmembrane domain interactions affect the stability of the extracellular domain of the human NTPDase 2.

Chiang WC, Knowles AF

Archives of biochemistry and biophysics 472(2) 89-99 2008年2月査読有り
Regulation of the human NTPDase 2 activity by its transmembrane domains

2008年査読有り
Enzymatic and transcriptional regulation of human ecto-ATPase/E-NTPDase 2

AF Knowles, WC Chiang

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 418(2) 217-227 2003年10月査読有り

MISC

Functional Diversity of Human ATF6 Mutations Associated with Achromatopsia

Wei-Chieh Chiang, Priscilla Chan, Susanne Kohl, Aioy Vincent, Anna Skorczyk-Werner, Maciej Robert Krawczynski, Stephen H. Tsang, Elise Heon, Bernd Wissinger, Jonathan H. Lin

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 57(12) 2016年9月
"ATF6 Promotes Early Stem Cell Development"

Heike Kroeger, Wei-Chieh Chiang, R. Luke Wiseman, Jonathan H. Lin

FASEB JOURNAL 30 2016年4月
Functional Diversity of Novel Disease Mutations in the Unfolded Protein Response regulator, ATF6

Wei-Chieh Chiang, Priscilla Chan, Jonathan H. Lin

FASEB JOURNAL 30 2016年4月
Mutations in the unfolded protein response regulator ATF6 cause the cone dysfunction disorder achromatopsia (vol 47, pg 757, 2015)

Susanne Kohl, Ditta Zobor, Wei-Chieh Chiang, Nicole Weisschuh, Jennifer Staller, Irene Gonzalez Menendez, Stanley Chang, Susanne C. Beck, Marina Garcia Garrido, Vithiyanjali Sothilingam …

NATURE GENETICS 47(7) 2015年7月
Mutations in the Unfolded Protein Response regulator, ATF6, cause Achromatopsia

Susanne Kohl, Ditta Zobor, Wei-Chieh Chiang, Nicole Weisschuh, Mathias W. Seeliger, Stanley Chang, Randal J. Kaufman, Stephen H. Tsang, Bernd Wissinger, Jonathan H. Lin

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 56(7) 2015年6月
bFGF Activates ATF6 to Trigger Differentiation of Human Embryonic Stem Cells

H. Kroeger, W-C. Chiang, M. Trejo, J. Genereux, N. J. Grimsey, M. D. Shoulder, E. Masliah, R. L. Wiseman, J. H. Lin

MOLECULAR BIOLOGY OF THE CELL 24 2013年
Chemical-genetic activation of the Unfolded Protein Response reduces protein misfolding

Wei-Chieh Chiang, Victory Joseph, Carissa Messah, Jonathan H. Lin

FASEB JOURNAL 24 2010年4月
Effects of pCMPS Modification of an Intramembrane Cysteine and Oxidative Cross linking of Transmembrane Domains on the Human NTPDase 2 Activity

Wei-Chieh Chiang, Aileen F. Knowles

FASEB JOURNAL 22 2008年4月
Regulation of human Ecto-ATPase (E-NTPase2) by its transmembranous domains

WC Chiang, AF Knowles

FASEB JOURNAL 20(5) A902-A902 2006年3月
Different regulation of human ecto-ATPase and chicken ecto-ATP-diphosphohydrolase

AF Knowles, WC Chiang, T Mukasa

FASEB JOURNAL 17(5) A998-A998 2003年3月

講演・口頭発表等

Unfolded Protein Response Regulator, ATF6, is Essential for Stress Survival in Cone Photoreceptors

Chiang Wei-Chieh

ARVO2019 2019年5月1日招待有り
Mutations in the Unfolded Protein Response Regulator Atf6 Cause the Cone Dysfunction Disorder Achromatopsia

Chiang Wei-Chieh

Pathology Research Lecture Series (PRLS), University of California, San Diego 2015年6月招待有り
Endoplasmic Reticulum-Associated Degradation (ERAD) of Misfolded Rhodopsin in Retinal Degeneration

Chiang Wei-Chieh

Cellular and Molecular Medicine (CMM) Symposium, University of California, San Diego 2014年3月招待有り
Chemical-genetic activation of the Unfolded Protein Response reduces protein misfolding

Chiang Wei-Chieh

Pathology Research Lecture Series (PRLS), University of California, San Diego 2010年6月招待有り
Chemical-genetic activation of the Unfolded Protein Response reduces protein misfolding

Chiang Wei-Chieh

Federation of American Societies for Experimental Biology (FASEB) conference 2010年4月招待有り
How does unfolded protein response affect misfolded rhodopsin?

Chiang Wei-Chieh

Cellular and Molecular Medicine (CMM) Seminar Series, University of California, San Diego 2010年3月招待有り

Wei-Chieh Chiang

基本情報

研究キーワード

研究分野

経歴

学歴

受賞

論文

MISC

講演・口頭発表等

担当経験のある科目(授業)

所属学協会

メニュー

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