米川博通 (Hiromichi Yonekawa) - マイポータル

基本情報

J-GLOBAL ID: 200901047478985694
researchmap会員ID: 0000035560

1974.4 東京教育大学大学院理学研究科博士課程修了
1975.4～1988.9 埼玉県立がんセンター研究所生化学部研究員、主任研究員
1986.10～1987.9 ハワードヒューズ医学研究所（UT Dallas) 客員研究員
1988.10～1999.11 (財)東京都臨床医学総合研究所実験動物研究部門室長、部長
1999.12～2010.3 (財)東京都臨床医学総合研究所副所長
2010.4～2011.3 (財)東京都臨床医学総合研究所基盤技術研究センター長兼
知的財産活用室室長
2011.4～2012.3 (財)東京都医学総合研究所基盤技術研究センター長兼
知的財産活用センター長
2012.4～2013.3 (公財)東京都医学総合研究所基盤技術研究センター遺伝子改変動物室客員研究員
2013.4～同シニア研究員

研究分野

ライフサイエンス / 実験動物学 /

経歴

1975年 - 1988年

埼玉県立がんセンター研究所・研究員・主任研究員
1975年 - 1988年

Saitama Cancer Center Research Institute
1988年

- (財)東京都臨床医学総合研究所室長・部長・副所長
1988年

The Tokyo Metropolitan Institute of Medical
Vice-Director
Science Department head, Department Director,
Investigator, Senior investigator

学歴

委員歴

日本実験動物学会, 理事、編集委員会委員長

受賞

論文

124

House mouse Mus musculus dispersal in East Eurasia inferred from 98 newly determined complete mitochondrial genome sequences

Yue Li, Kazumichi Fujiwara, Naoki Osada, Yosuke Kawai, Toyoyuki Takada, Alexey P. Kryukov, Kuniya Abe, Hiromichi Yonekawa, Toshihiko Shiroishi, Kazuo Moriwaki, Naruya Saitou, Hitoshi Suzuki

Heredity 126(1) 132-147 2021年1月
OHC-TRECK: A Novel System Using a Mouse Model for Investigation of the Molecular Mechanisms Associated with Outer Hair Cell Death in the Inner Ear.

Matsuoka K, Wada K, Miyasaka Y, Yasuda SP, Seki Y, Nishito Y, Yonekawa H, Taya C, Shitara H, Kikkawa Y

Sci Rep 9(1) 5285 2019年3月査読有り
Mice deficient in the Shmt2 gene have mitochondrial respiration defects and are embryonic lethal

Haruna Tani, Sakiko Ohnishi, Hiroshi Shitara, Takayuki Mito, Midori Yamaguchi, Hiromichi Yonekawa, Osamu Hashizume, Kaori Ishikawa, Kazuto Nakada, Jun-Ichi Hayashi

Scientific Reports 8(1) 425 2018年12月1日査読有り
Skin CD4(+) Memory T Cells Play an Essential Role in Acquired Anti-Tick Immunity through Interleukin-3-Mediated Basophil Recruitment to Tick-Feeding Sites

Takuya Ohta, Soichiro Yoshikawa, Yuya Tabakawa, Kayoko Yamaji, Kenji Ishiwata, Hiroshi Shitara, Choji Taya, Masatsugu Oh-hora, Yohei Kawano, Kensuke Miyake, Yoshinori Yamanishi, Hiromichi Yonekawa, Naohiro Watanabe, Hirotaka Kanuka, Hajime Karasuyama

FRONTIERS IN IMMUNOLOGY 8 1348 2017年10月査読有り
Establishment of a heteroplasmic mouse strain with interspecific mitochondrial DNA haplotypes and improvement of a PCR-RFLP-based measurement system for estimation of mitochondrial DNA heteroplasmy

Hiroshi Shitara, Liqin Cao, Midori Yamaguchi, Hiromichi Yonekawa, Choji Taya

TRANSGENIC RESEARCH 26(4) 559-565 2017年8月査読有り
Heterozygous mutation of Ush1g/Sans in mice causes early-onset progressive hearing loss, which is recovered by reconstituting the strain-specific mutation in Cdh23

Yuki Miyasaka, Hiroshi Shitara, Sari Suzuki, Sachi Yoshimoto, Yuta Seki, Yasuhiro Ohshiba, Kazuhiro Okumura, Choji Taya, Hisashi Tokano, Ken Kitamura, Toyoyuki Takada, Hiroshi Hibino, Toshihiko Shiroishi, Ryo Kominami, Hiromichi Yonekawa, Yoshiaki Kikkawa

HUMAN MOLECULAR GENETICS 25(10) 2045-2059 2016年5月査読有り
Essential Contribution of CD4(+) T Cells to Antigen-Induced Nasal Hyperresponsiveness in Experimental Allergic Rhinitis

Tomoe Nishimura, Osamu Kaminuma, Mayumi Saeki, Noriko Kitamura, Kunie Matsuoka, Hiromichi Yonekawa, Akio Mori, Takachika Hiroi

PLOS ONE 11(1) e0146686 2016年1月査読有り
Mouse somatic mutation orthologous to MELAS A3302G mutation in the mitochondrial tRNA(Leu(UUR)) gene confers respiration defects

Akinori Shimizu, Shunkei Enoki, Kaori Ishikawa, Takayuki Mito, Kanae Obata, Ruriko Nagashima, Hiromichi Yonekawa, Kazuto Nakada, Jun-Ichi Hayashi

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 467(4) 1097-1102 2015年11月査読有り
G7731A mutation in mouse mitochondrial tRNA(LYs) regulates late-onset disorders in transmitochondrial mice

Akinori Shimizu, Takayuki Mito, Osamu Hashizume, Hiromichi Yonekawa, Kaori Ishikawa, Kazuto Nakada, Jun-ichi Hayashi

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 459(1) 66-70 2015年3月査読有り
Administration of an Antioxidant Prevents Lymphoma Development in Transmitochondrial Mice Overproducing Reactive Oxygen Species

Haruka Yamanashi, Osamu Hashizume, Hiromichi Yonekawa, Kazuto Nakada, Jun-Ichi Hayashi

EXPERIMENTAL ANIMALS 63(4) 459-466 2014年10月査読有り
Evolutionary and dispersal history of Eurasian house mice Mus musculus clarified by more extensive geographic sampling of mitochondrial DNA

H. Suzuki, M. Nunome, G. Kinoshita, K. P. Aplin, P. Vogel, A. P. Kryukov, M-L Jin, S-H Han, I. Maryanto, K. Tsuchiya, H. Ikeda, T. Shiroishi, H. Yonekawa, K. Moriwaki

HEREDITY 111(5) 375-390 2013年11月査読有り
Compound Heterozygosity of the Functionally Null Cdh23(v-ngt) and Hypomorphic Cdh23(ahl) Alleles Leads to Early-onset Progressive Hearing Loss in Mice

Yuki Miyasaka, Sari Suzuki, Yasuhiro Ohshiba, Kei Watanabe, Yoshihiko Sagara, Shumpei P. Yasuda, Kunie Matsuoka, Hiroshi Shitara, Hiromichi Yonekawa, Ryo Kominami, Yoshiaki Kikkawa

EXPERIMENTAL ANIMALS 62(4) 333-346 2013年10月査読有り
Generation of mouse models for type 1 diabetes by selective depletion of pancreatic beta cells using toxin receptor-mediated cell knockout

Kunie Matsuoka, Michiko Saito, Kosuke Shibata, Michiko Sekine, Hiroshi Shitara, Choji Taya, Xiaohong Zhang, Tsuneo A. Takahashi, Kenji Kohno, Yoshiaki Kikkawa, Hiromichi Yonekawa

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 436(3) 400-405 2013年7月査読有り
Development of Lymphoproliferative Diseases by Hypoxia Inducible Factor-1alpha Is Associated with Prolonged Lymphocyte Survival

Eisaburo Sueoka, Naoko Sueoka-Aragane, Akemi Sato, Masaru Ide, Hideaki Nakamura, Yusuke Sotomaru, Choji Taya, Hiromichi Yonekawa, Tomoyuki Kitagawa, Yasushi Kubota, Shinya Kimura, Kei Nakachi, Keiji Tanimoto

PLoS ONE 8(4) e57833 2013年4月12日査読有り
Novel Basophil- or Eosinophil-Depleted Mouse Models for Functional Analyses of Allergic Inflammation

Kunie Matsuoka, Hiroshi Shitara, Choji Taya, Kenji Kohno, Yoshiaki Kikkawa, Hiromichi Yonekawa

PLOS ONE 8(4) e60958 2013年4月査読有り
Existence of Antigen-Specific Immunoglobulin E Is Not Sufficient for Allergic Nasal Eosinophil Infiltration in Mice

Tomoe Nishimura, Mayumi Saeki, Osamu Kaminuma, Kunie Matsuoka, Hiromichi Yonekawa, Akio Mori, Takachika Hiroi

INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY 161 125-128 2013年査読有り
Mitochondrial Physiology and Gene Expression Analyses Reveal Metabolic and Translational Dysregulation in Oocyte-Induced Somatic Nuclear Reprogramming

Telma C. Esteves, Olympia E. Psathaki, Martin J. Pfeiffer, Sebastian T. Balbach, Dagmar Zeuschner, Hiroshi Shitara, Hiromichi Yonekawa, Marcin Siatkowski, Georg Fuellen, Michele Boiani

PLOS ONE 7(6) e36850 2012年6月査読有り
Comprehensive application of an mtDsRed2-Tg mouse strain for mitochondrial imaging

Junya Yamaguchi, Satoshi Nishiyama, Midori Shimanuki, Tomio Ono, Akitsugu Sato, Kazuto Nakada, Jun-Ichi Hayashi, Hiromichi Yonekawa, Hiroshi Shitara

TRANSGENIC RESEARCH 21(2) 439-447 2012年4月査読有り
Advantages of a Mouse Model for Human Hearing Impairment

Yoshiaki Kikkawa, Yuta Seki, Kazuhiro Okumura, Yasuhiro Ohshiba, Yuki Miyasaka, Sari Suzuki, Mao Ozaki, Kunie Matsuoka, Yoshihiro Noguchi, Hiromichi Yonekawa

EXPERIMENTAL ANIMALS 61(2) 85-98 2012年4月査読有り
Mouse Models for Atopic Dermatitis Developed in Japan

Hiromichi Yonekawa, Toyoyuki Takada, Hiroshi Shitara, Choji Taya, Yoshibumi Matsushima, Kunie Matsuoka, Yoshiaki Kikkaw

Atopic Dermatitis - Disease Etiology and Clinical Management 2012年2月22日