由良義充 (Yoshimitsu Yura) - マイポータル

基本情報

所属: 名古屋大学附属病院循環器内科病院助教

研究者番号: 60943305
J-GLOBAL ID: 202101015506815747
researchmap会員ID: R000031743

経歴

2021年10月 - 現在

名古屋大学医学部附属病院循環器内科病院助教
2021年5月 - 2021年9月

バージニア大学医学部循環器内科助教
2018年4月 - 2021年4月

バージニア大学医学部心血管研究所博士研究員
2017年4月 - 2018年3月

ボストン大学医学部血管生物学部門博士研究員

学歴

2012年4月 - 2016年3月

名古屋大学大学院医学系研究科
2001年4月 - 2007年3月

名古屋大学医学部

論文

The Cancer Therapy-Related Clonal Hematopoiesis Driver Gene Ppm1d Promotes Inflammation and Non-Ischemic Heart Failure in Mice.

Yoshimitsu Yura, Emiri Miura-Yura, Yasufumi Katanasaka, Kyung-Duk Min, Nicholas Chavkin, Ariel H Polizio, Hayato Ogawa, Keita Horitani, Heather Doviak, Megan A Evans, Miho Sano, Ying Wang, Katharina Boroviak, George Philippos, Ana Filipa Domingues, George Vassiliou, Soichi Sano, Kenneth Walsh

Circulation research 129(6) 684-698 2021年9月3日
TP53-mediated therapy-related clonal hematopoiesis contributes to doxorubicin-induced cardiomyopathy by augmenting a neutrophil-mediated cytotoxic response.

Soichi Sano, Ying Wang, Hayato Ogawa, Keita Horitani, Miho Sano, Ariel H Polizio, Anupreet Kour, Yoshimitsu Yura, Heather Doviak, Kenneth Walsh

JCI insight 6(13) 2021年7月8日
Murine models of clonal hematopoiesis to assess mechanisms of cardiovascular disease.

Ying Wang, Soichi Sano, Hayato Ogawa, Keita Horitani, Megan A Evans, Yoshimitsu Yura, Emiri Miura-Yura, Heather Doviak, Kenneth Walsh

Cardiovascular research 2021年6月23日
Bone Marrow Transplantation Procedures in Mice to Study Clonal Hematopoiesis.

Eunbee Park, Megan A Evans, Heather Doviak, Keita Horitani, Hayato Ogawa, Yoshimitsu Yura, Ying Wang, Soichi Sano, Kenneth Walsh

Journal of visualized experiments : JoVE (171) 2021年5月26日
Tet2-mediated clonal hematopoiesis in nonconditioned mice accelerates age-associated cardiac dysfunction.

Ying Wang, Soichi Sano, Yoshimitsu Yura, Zhonghe Ke, Miho Sano, Kosei Oshima, Hayato Ogawa, Keita Horitani, Kyung-Duk Min, Emiri Miura-Yura, Anupreet Kour, Megan A Evans, Maria A Zuriaga, Karen K Hirschi, Jose J Fuster, Eric M Pietras, Kenneth Walsh

JCI insight 5(6) 2020年3月26日
Clonal Hematopoiesis: A New Step Linking Inflammation to Heart Failure.

Yoshimitsu Yura, Soichi Sano, Kenneth Walsh

JACC. Basic to translational science 5(2) 196-207 2020年2月
Phosphorylation of Npas4 by MAPK Regulates Reward-Related Gene Expression and Behaviors.

Yasuhiro Funahashi, Anthony Ariza, Ryosuke Emi, Yifan Xu, Wei Shan, Ko Suzuki, Sachi Kozawa, Rijwan Uddin Ahammad, Mengya Wu, Tetsuya Takano, Yoshimitsu Yura, Keisuke Kuroda, Taku Nagai, Mutsuki Amano, Kiyofumi Yamada, Kozo Kaibuchi

Cell reports 29(10) 3235-3252 2019年12月3日
Endothelial cell-specific redox gene modulation inhibits angiogenesis but promotes B16F0 tumor growth in mice.

Yoshimitsu Yura, Brian S H Chong, Ryan D Johnson, Yosuke Watanabe, Yuko Tsukahara, Beatriz Ferran, Colin E Murdoch, Jessica B Behring, Mark E McComb, Catherine E Costello, Yvonne M W Janssen-Heininger, Richard A Cohen, Markus M Bachschmid, Reiko Matsui

FASEB journal : official publication of the Federation of American Societies for Experimental Biology 33(12) 14147-14158 2019年12月
Protein Kinase N Promotes Stress-Induced Cardiac Dysfunction Through Phosphorylation of Myocardin-Related Transcription Factor A and Disruption of Its Interaction With Actin.

Teruhiro Sakaguchi, Mikito Takefuji, Nina Wettschureck, Tomonari Hamaguchi, Mutsuki Amano, Katsuhiro Kato, Takuma Tsuda, Shunsuke Eguchi, Sohta Ishihama, Yu Mori, Yoshimitsu Yura, Tatsuya Yoshida, Kazumasa Unno, Takahiro Okumura, Hideki Ishii, Yuuki Shimizu, Yasuko K Bando, Koji Ohashi, Noriyuki Ouchi, Atsushi Enomoto, Stefan Offermanns, Kozo Kaibuchi, Toyoaki Murohara

Circulation 140(21) 1737-1752 2019年11月19日
Lentiviral CRISPR/Cas9-Mediated Genome Editing for the Study of Hematopoietic Cells in Disease Models.

Soichi Sano, Ying Wang, Megan A Evans, Yoshimitsu Yura, Miho Sano, Hayato Ogawa, Keita Horitani, Heather Doviak, Kenneth Walsh

Journal of visualized experiments : JoVE (152) 2019年10月3日
JAK2 V617F -Mediated Clonal Hematopoiesis Accelerates Pathological Remodeling in Murine Heart Failure.

Soichi Sano, Ying Wang, Yoshimitsu Yura, Miho Sano, Kosei Oshima, Yue Yang, Yasufumi Katanasaka, Kyung-Duk Min, Shinobu Matsuura, Katya Ravid, Golam Mohi, Kenneth Walsh

JACC. Basic to translational science 4(6) 684-697 2019年10月
Wnt5a-Mediated Neutrophil Recruitment Has an Obligatory Role in Pressure Overload-Induced Cardiac Dysfunction.

Ying Wang, Soichi Sano, Kosei Oshima, Miho Sano, Yosuke Watanabe, Yasufumi Katanasaka, Yoshimitsu Yura, Changhee Jung, Atsushi Anzai, Filip K Swirski, Noyan Gokce, Kenneth Walsh

Circulation 140(6) 487-499 2019年8月6日
Discovery of long-range inhibitory signaling to ensure single axon formation.

Tetsuya Takano, Mengya Wu, Shinichi Nakamuta, Honda Naoki, Naruki Ishizawa, Takashi Namba, Takashi Watanabe, Chundi Xu, Tomonari Hamaguchi, Yoshimitsu Yura, Mutsuki Amano, Klaus M Hahn, Kozo Kaibuchi

Nature communications 8(1) 33-33 2017年6月26日
Identification of Protein Kinase Substrates by the Kinase-Interacting Substrate Screening (KISS) Approach.

Mutsuki Amano, Tomoki Nishioka, Yoshimitsu Yura, Kozo Kaibuchi

Current protocols in cell biology 72 14.16.1-14.16.12 2016年9月1日
Focused Proteomics Revealed a Novel Rho-kinase Signaling Pathway in the Heart.

Yoshimitsu Yura, Mutsuki Amano, Mikito Takefuji, Tomohiro Bando, Kou Suzuki, Katsuhiro Kato, Tomonari Hamaguchi, Md Hasanuzzaman Shohag, Tetsuya Takano, Yasuhiro Funahashi, Shinichi Nakamuta, Keisuke Kuroda, Tomoki Nishioka, Toyoaki Murohara, Kozo Kaibuchi

Cell structure and function 41(2) 105-20 2016年8月23日
Kinase-interacting substrate screening is a novel method to identify kinase substrates.

Mutsuki Amano, Tomonari Hamaguchi, Md Hasanuzzaman Shohag, Kei Kozawa, Katsuhiro Kato, Xinjian Zhang, Yoshimitsu Yura, Yoshiharu Matsuura, Chikako Kataoka, Tomoki Nishioka, Kozo Kaibuchi

The Journal of cell biology 209(6) 895-912 2015年6月22日
In vivo screening for substrates of protein kinase A using a combination of proteomic approaches and pharmacological modulation of kinase activity.

Tomonari Hamaguchi, Shinichi Nakamuta, Yasuhiro Funahashi, Tetsuya Takano, Tomoki Nishioka, Md Hasanuzzaman Shohag, Yoshimitsu Yura, Kozo Kaibuchi, Mutsuki Amano

Cell structure and function 40(1) 1-12 2015年
New-onset atrial fibrillation may be a more important predictor of cardiac mortality in acute myocardial infarction patients than preexisting atrial fibrillation.

Itsuro Morishima, Toshiro Tomomatsu, Kenji Okumura, Takahito Sone, Hideyuki Tsuboi, Yasuhiro Morita, Yosuke Inoue, Ruka Yoshida, Yoshimitsu Yura, Toyoaki Murohara

International journal of cardiology 187 475-7 2015年
Phosphoproteomic Analysis Using the WW and FHA Domains as Biological Filters.

Md Hasanuzzaman Shohag, Tomoki Nishioka, Rijwan Uddin Ahammad, Shinichi Nakamuta, Yoshimitsu Yura, Tomonari Hamaguchi, Kozo Kaibuchi, Mutsuki Amano

Cell structure and function 40(2) 95-104 2015年
RhoGEF-mediated vasoconstriction in hypertension.

Mikito Takefuji, Yoshimitsu Yura, Kozo Kaibuchi, Toyoaki Murohara

Hypertension research : official journal of the Japanese Society of Hypertension 36(11) 930-1 2013年11月