2023年1月4日
Upregulation of MAP kinase HOG1 gene of white-rot fungus Phlebia sp. MG-60 inhibits the ethanol fermentation and mycelial growth
Bioscience, Biotechnology, and Biochemistry
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- 巻
- 87
- 号
- 2
- 開始ページ
- 217
- 終了ページ
- 227
- 記述言語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1093/bbb/zbac203
- 出版者・発行元
- Oxford University Press ({OUP})
Wood biomass conversion for fossil resource replacement could result in the sustainable production of chemicals, although lignin represents an obstacle to efficient polysaccharide use. White-rot fungus Phlebia sp. MG-60 reportedly selectively and aerobically degrades lignin in hardwood, then it begins cellulose saccharification from the delignified wood to produce ethanol. Environmental conditions might change white-rot fungi-driven biomass conversion. However, how the environmental response sensor affects ethanol fermentation in white-rot fungi remains elusive. In this study, we focused on MGHOG1, the yeast Hog1 homolog in Phlebia sp. MG-60, a presumably important player in osmoresponse. We generated MGHOG1 overexpressing (OE) transformants in Phlebia sp. MG-60, exhibiting slower mycelial growth compared with the wild-type under salinity stress. MGHOG1 overexpressing liquid cultures displayed suppressed mycelial growth and ethanol fermentation. Therefore, MGHOG1 potentially influences ethanol fermentation and mycelial growth in Phlebia sp. MG-60. This study provides novel insights into the regulation of white-rot fungi-mediated biomass conversion.
- リンク情報
- ID情報
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- DOI : 10.1093/bbb/zbac203
- ISSN : 1347-6947
- eISSN : 1347-6947
- ORCIDのPut Code : 126175639
- PubMed ID : 36610726
- SCOPUS ID : 85147047293