2011年
Characteristics of Ventricular Tachycardia in Drug-Refractory Electrical Storm in ICD Patients with Structural Heart Disease
journal of arrhythmia
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- 巻
- 27
- 号
- 開始ページ
- 194
- 終了ページ
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.4020/jhrs.27.OP06_3
Objective: The aim of the present study was to assess characteristics of ventricular tachycardia (VT) of electrical storm (ES) in ICD patients with structural heart disease. Methods: We included 156 consecutive patients who implanted ICD due to secondary prevention. ES was defined as the occurrence of at least 3 episodes of VT/VF within 24-hours. Basic treatment for ES was as follows
sedation, β-blockers, and class I and/or III antiarrhythmic drugs. We defined that elimination of ES for 2 weeks after basic treatment was drug effective (DE), if not, drug refractory (DR). Results: During a mean follow-up period of 54 ± 37 months, ES occurred in 42 patients (OMI in 12, DCM in 15, HCM in 6, ARVC in 5, cardiac sarcoidosis in 4). Patients with DE and DR were 30 and 12 patients, respectively. There were no significant differences in age, sex, and LVEF. However, cycle length of VT (VTCL) was significantly longer in patients with DR than with DE (384 ± 16 vs. 305 ± 10 ms, p<
0.05). All 12 patients with DE required for Catheter ablation. Conclusion: Longer VTCL in ES was related to drug refractoriness, which might be caused by stability of reentry circuit in spite of antiarrhythmic therapy. © 2011, Japanese Heart Rhythm Society. All rights reserved.
sedation, β-blockers, and class I and/or III antiarrhythmic drugs. We defined that elimination of ES for 2 weeks after basic treatment was drug effective (DE), if not, drug refractory (DR). Results: During a mean follow-up period of 54 ± 37 months, ES occurred in 42 patients (OMI in 12, DCM in 15, HCM in 6, ARVC in 5, cardiac sarcoidosis in 4). Patients with DE and DR were 30 and 12 patients, respectively. There were no significant differences in age, sex, and LVEF. However, cycle length of VT (VTCL) was significantly longer in patients with DR than with DE (384 ± 16 vs. 305 ± 10 ms, p<
0.05). All 12 patients with DE required for Catheter ablation. Conclusion: Longer VTCL in ES was related to drug refractoriness, which might be caused by stability of reentry circuit in spite of antiarrhythmic therapy. © 2011, Japanese Heart Rhythm Society. All rights reserved.
- ID情報
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- DOI : 10.4020/jhrs.27.OP06_3
- ISSN : 1883-2148
- ISSN : 1880-4276
- SCOPUS ID : 85009628133