2017年7月
Proton Beam Therapy for Pediatric Brain Tumor
NEUROLOGIA MEDICO-CHIRURGICA
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- 巻
- 57
- 号
- 7
- 開始ページ
- 343
- 終了ページ
- 355
- 記述言語
- 英語
- 掲載種別
- DOI
- 10.2176/nmc.ra.2017-0003
- 出版者・発行元
- JAPAN NEUROSURGICAL SOC
Cancer is a major cause of childhood death, with central nervous system (CNS) neoplasms being the second most common pediatric malignancy, following hematological cancer. Treatment of pediatric CNS malignancies requires multimodal treatment using a combination of surgery, chemotherapy, and radiotherapy, and advances in these treatments have given favorable results and longer survival. However, treatment-related toxicities have also occurred, particularly for radiotherapy, after which secondary cancer, reduced function of irradiated organs, and retarded growth are significant problems. Proton beam therapy (PBT) is a particle radiotherapy with excellent dose localization that permits treatment of liver and lung cancer by administration of a high dose to the tumor while minimizing damage to surrounding normal tissues. Thus, PBT has the potential advantages for pediatric cancer. In this context, we review the current knowledge on PBT for treatment of pediatric CNS malignancies.
- リンク情報
- ID情報
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- DOI : 10.2176/nmc.ra.2017-0003
- ISSN : 0470-8105
- eISSN : 1349-8029
- PubMed ID : 28603224
- Web of Science ID : WOS:000409947700005