論文

査読有り
2017年

Body fat mass is correlated with serum transthyretin levels in maintenance hemodialysis patients

Journal of Medical Investigation
  • Sayaka Matsuura
  • Yumiko Shirai
  • Miyu Kubo
  • Chisako Nayama
  • Masami Okitsu
  • Yuu Oiwa
  • Sonoko Yasui
  • Yoshiko Suzuki
  • Tomohiro Murata
  • Eiji Ishikawa
  • Chikao Miki
  • Yasuhiro Hamada
  • 全て表示

64
3-4
開始ページ
222
終了ページ
227
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.2152/jmi.64.222
出版者・発行元
University of Tokushima

Serum transthyretin (TTR), also known as prealbumin, is a reliable nutritional indicator and an independent prognostic factor for maintenance hemodialysis patients. However, we recently reported that serum TTR levels did not affect protein−energy wasting (PEW). In this study, we investigated factors affecting serum TTR levels in 60 maintenance hemodialysis patients. The patients were divided into High-TTR and Low-TTR groups according to the median serum TTR level. Albumin levels were significantly higher and C-reactive protein (CRP) levels were significantly lower in the High-TTR group than in the Low-TTR group. Although body fat mass was significantly higher in the High-TTR group than in the Low-TTR group, no significant difference in body fat ratio were observed. These findings suggest that body fat mass is related to serum TTR levels, apart from factors such as albumin and CRP levels, which showed correlations with serum TTR levels. Because body fat mass is related to better survival in maintenance hemodialysis patients, it may contribute to the prognostic value of serum TTR levels. In addition, in such patients, it may be important to evaluate body fat mass rather than body fat ratio and to maintain the minimum necessary body fat mass.

リンク情報
DOI
https://doi.org/10.2152/jmi.64.222
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/28954986
ID情報
  • DOI : 10.2152/jmi.64.222
  • ISSN : 1349-6867
  • ISSN : 1343-1420
  • PubMed ID : 28954986
  • SCOPUS ID : 85030261792

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