論文

査読有り
2013年

Lactobacillus plantarum OLL2712 Regulates Glucose Metabolism in C57BL/6 Mice Fed a High-Fat Diet

Journal of Nutritional Science and Vitaminology
  • Tohru SAKAI
  • ,
  • Tomoyo TAKI
  • ,
  • Akiko NAKAMOTO
  • ,
  • Emi SHUTO
  • ,
  • Rie TSUTSUMI
  • ,
  • Takayuki TOSHIMITSU
  • ,
  • Seiya MAKINO
  • ,
  • Shuuji IKEGAMI

59
2
開始ページ
144
終了ページ
147
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.3177/jnsv.59.144
出版者・発行元
Center for Academic Publications Japan

The aim of the present study was to determine the effect of oral administration of Lactobacillus plantarum OLL2712 (L. plantarum OLL2712) on glucose and lipid metabolism in mice with high-fat diet-induced obesity. Mice that had been administered 10(9) cfu heat-killed L. plantarum OLL2712 for 12 wk showed significant reduction of blood glucose levels in response to insulin. Furthermore, mRNA expression of interleukin-1β in adipose tissue and serum levels of nonesterified fatty acids in mice administered L. plantarum OLL2712 were significantly lower than those in control mice. These results indicate that L. plantarum OLL2712 regulates glucose metabolism.

リンク情報
DOI
https://doi.org/10.3177/jnsv.59.144
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/23727645
ID情報
  • DOI : 10.3177/jnsv.59.144
  • ISSN : 0301-4800
  • eISSN : 1881-7742
  • PubMed ID : 23727645

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