古川亜矢子 (Ayako Furukawa) - マイポータル

基本情報

ORCID iD: https://orcid.org/0000-0002-7339-4632
J-GLOBAL ID: 201801000176060105
researchmap会員ID: B000312927

外部リンク: https://researchmap.jp/a_a

研究キーワード

構造生物学

研究分野

ライフサイエンス / 構造生物化学 /

受賞

2021年8月

進歩賞, 溶液NMR法を用いた核酸-タンパク質の動的な相互作用の機構解明, 日本核磁気共鳴学会
2011年11月

第50回NMR討論会記念国際シンポジウム若手ポスター賞, 日本核磁気共鳴学会

古川亜矢子

論文

Development of a Real-Time Monitoring System for the Adherent Human Keratinocyte Metabolism by Live-Cell Metabolic NMR with Illumination.

Makoto Uyama, Yuki Umino, Fumio Matsuda, Ayako Furukawa, Kenji Sugase, Takahisa Ikegami

Analytical chemistry 97(41) 22624-22631 2025年10月21日
Purification tags markedly affect self-aggregation of CPEB3.

Harunobu Saito, Yujin Lee, Motoharu Ueno, Naotaka Sekiyama, Masatomo So, Ayako Furukawa, Kenji Sugase

FEBS letters 2025年6月17日査読有り
Backbone resonance assignments of the CPEB3 [101-200] and CPEB3 [294-410].

Harunobu Saito, Yujin Lee, Tomoharu Ueno, Naotaka Sekiyama, Masatomo So, Ayako Furukawa, Kenji Sugase

Biomolecular NMR assignments 2025年3月29日査読有り
A dynamic structural unit of phase-separated heterochromatin protein 1α as revealed by integrative structural analyses.

Ayako Furukawa, Kento Yonezawa, Tatsuki Negami, Yuriko Yoshimura, Aki Hayashi, Jun-Ichi Nakayama, Naruhiko Adachi, Toshiya Senda, Kentaro Shimizu, Tohru Terada …

Nucleic acids research 53(6) 2025年3月20日査読有り筆頭著者
Bipartite binding interface recruiting HP1 to chromosomal passenger complex at inner centromeres.

Kosuke Sako, Ayako Furukawa, Ryu-Suke Nozawa, Jun-Ichi Kurita, Yoshifumi Nishimura, Toru Hirota

The Journal of cell biology 223(9) 2024年9月2日査読有り
H2A ubiquitination alters H3-tail dynamics on linker-DNA to enhance H3K27 methylation

Hideaki Ohtomo, Shinsuke Ito, Nicholas J. McKenzie, Michael Uckelmann, Masatoshi Wakamori, Haruhiko Ehara, Ayako Furukawa, Yasuo Tsunaka, Marika Shibata, Shun-ichi Sekine …

Journal of Molecular Biology 167936-167936 2023年1月査読有り
Histone tail network and modulation in a nucleosome.

Yasuo Tsunaka, Ayako Furukawa, Yoshifumi Nishimura

Current opinion in structural biology 75 102436-102436 2022年7月18日査読有り筆頭著者
Characteristic H3 N-tail dynamics in the nucleosome core particle, nucleosome, and chromatosome

Ayako Furukawa, Masatoshi Wakamori, Yasuhiro Arimura, Hideaki Ohtomo, Yasuo Tsunaka, Hitoshi Kurumizaka, Takashi Umehara, Yoshifumi Nishimura

iScience 25(3) 103937-103937 2022年3月査読有り筆頭著者
Structural dynamics of double-stranded DNA with epigenome modification.

Ayako Furukawa, Erik Walinda, Kyohei Arita, Kenji Sugase

Nucleic acids research 49(2) 1152-1162 2020年12月18日査読有り筆頭著者
Acetylated histone H4 tail enhances histone H3 tail acetylation by altering their mutual dynamics in the nucleosome.

Ayako Furukawa, Masatoshi Wakamori, Yasuhiro Arimura, Hideaki Ohtomo, Yasuo Tsunaka, Hitoshi Kurumizaka, Takashi Umehara, Yoshifumi Nishimura

Proceedings of the National Academy of Sciences of the United States of America 117(33) 19661-19663 2020年8月18日査読有り筆頭著者
Identification of a binding protein for sesamin and characterization of its roles in plant growth.

Masayuki Tera, Tomotsugu Koyama, Jun Murata, Ayako Furukawa, Shoko Mori, Toshiaki Azuma, Takehiro Watanabe, Katsuhito Hori, Atsushi Okazawa, Yasuaki Kabe …

Scientific reports 9(1) 8631-8631 2019年6月14日査読有り
Quantitative analysis of protein-ligand interactions by NMR

Ayako Furukawa, Tsuyoshi Konuma, Saeko Yanaka, Kenji Sugase

PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY 96 47-57 2016年8月査読有り筆頭著者
Dynamic changes in CCAN organization through CENP-C during cell-cycle progression

Harsh Nagpal, Tetsuya Hori, Ayako Furukawa, Kenji Sugase, Akihisa Osakabe, Hitoshi Kurumizaka, Tatsuo Fukagawa

MOLECULAR BIOLOGY OF THE CELL 26(21) 3768-3776 2015年11月査読有り
Quantitative analysis of location- and sequence-dependent deamination by APOBEC3G using real-time NMR spectroscopy.

Furukawa A, Sugase K, Morishita R, Nagata T, Kodaki T, Takaori-Kondo A, Ryo A, Katahira M

Angew Chem Int Ed Engl 53(9) 2349-2352 2014年2月査読有り筆頭著者
Molecular and enzymatic characterization of XMRV protease by a cell-free proteolytic analysis

Satoko Matsunaga, Tatsuya Sawasaki, Hirotaka Ode, Ryo Morishita, Ayako Furukawa, Ryuta Sakuma, Wataru Sugiura, Hironori Sato, Masato Katahira, Akifumi Takaori-Kondo …

JOURNAL OF PROTEOMICS 75(15) 4863-4873 2012年8月査読有り
NMR study of xenotropic murine leukemia virus-related virus protease in a complex with amprenavir

Ayako Furukawa, Hideyasu Okamura, Ryo Morishita, Satoko Matsunaga, Naohiro Kobayashi, Takahisa Ikegami, Tsutomu Kodaki, Akifumi Takaori-Kondo, Akihide Ryo, Takashi Nagata …

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 425(2) 284-289 2012年8月査読有り筆頭著者
Heat Shock Protein 70 Inhibits HIV-1 Vif-mediated Ubiquitination and Degradation of APOBEC3G

Ryuichi Sugiyama, Hironori Nishitsuji, Ayako Furukawa, Masato Katahira, Yuichiro Habu, Hiroaki Takeuchi, Akihide Ryo, Hiroshi Takaku

JOURNAL OF BIOLOGICAL CHEMISTRY 286(12) 10051-10057 2011年3月査読有り
抗HIVタンパク質APOBEC3Gの酵素反応のNMRによるリアルタイムモニタリング

古川亜矢子

生物物理 50(5) 240-241 2010年9月25日
Structure, interaction and real-time monitoring of the enzymatic reaction of wild-type APOBEC3G

Ayako Furukawa, Takashi Nagata, Akimasa Matsugami, Yuichirou Habu, Ryuichi Sugiyama, Fumiaki Hayashi, Naohiro Kobayashi, Shigeyuki Yokoyama, Hiroshi Takaku, Masato Katahira

EMBO JOURNAL 28(4) 440-451 2009年2月査読有り
Structure and real-time monitoring of the enzymatic reaction of APOBEC3G which is involved in anti-HIV activity.

Furukawa A, Nagata T, Matsugami A, Habu Y, Sugiyama R, Hayashi F, Kobayashi N, Yokoyama S, Takaku H, Katahira M

Nucleic acids symposium series (2004) 53(53) 87-88 2009年査読有り