Andrei R. Akhmetzhanov

J-GLOBAL         Last updated: Sep 16, 2019 at 16:49
Andrei R. Akhmetzhanov
Hokkaido University
Graduate School of Medicine
Job title
Assistant Professor
PhD in Mathematics and Physics(Moscow Institute of Physics and Technology (State University), Russia)
Twitter ID


Applied mathematician working in Infectious disease modeling

Research Areas


Academic & Professional Experience

Mar 2019
Assistant Professor, Grad School of Medicine, Hokkaido University
Jan 2017
Mar 2019
Postdoc, Graduate School of Medicine, Department of Hygiene, Hokkaido University, Sapporo, Japan
Apr 2015
Dec 2016
Postdoc, Institute of Statistical Sciences, Academia Sinica, Taipei, Taiwan
Dec 2012
Dec 2014
Postdoc, Institute of Evolutionary Sciences in Montpelier (ISEM), University of Montpelier 2, Montpellier, France
Apr 2011
Dec 2012
Postdoc, Department of Biology and Department of Mathematics and Statistics,, McMaster University, Hamilton, Ontario, Canada


Sep 2006
Dec 2009
Ph.D. Program in Theoretical Mechanics, Dept of Control Systems at Institute of Problems in Mechanics of the Russian Academy of Sciences, Moscow, Russia, Moscow Institute of Physics and Technology (State University), Moscow, Russia
Sep 2004
Jun 2006
Master of Sciences (M.Sc.), Diploma with Honors, Dept of Aerophysics and Space Research, Moscow Institute of Physics and Technology (State University)
Sep 2000
Jun 2004
Bachelor of Sciences (B.Sc.), Diploma with Honors, Dept of Aerophysics and Space Research, Moscow Institute of Physics and Technology (State University), Moscow, Russia

Awards & Honors

XII International Olympiad on Automatic Control (Baltic Olympiad), St. Petersburg, Russia, 1st place diploma in a theoretical part
13th International Symposium on Dynamic Games and Applications, Wroclaw, Poland, Leading work in the competition of young participants contributions
Jun 2006
M.Sc., Moscow Institute of Physics and Technology (State University), Diploma with Honors
XI International Olympiad on Automatic Control (Baltic Olympiad), St. Petersburg, 3rd place diploma in a theoretical part
Jun 2004
B.Sc., Moscow Institute of Physics and Technology (State University), Diploma with Honors

Published Papers

Akhmetzhanov AR, Kim JW, Sullivan R, Beckman RA, Tamayo P, Yeang C-H
Journal of theoretical biology   474 88-102   Aug 2019   [Refereed]
Despite recent advances in targeted drugs and immunotherapy, cancer remains “the emperor of all maladies” due to almost inevitable emergence of resistance. Drug resistance is thought to be driven by genetic alterations and/or dynamic plasticity th...
Akhmetzhanov AR, Lee H, Jung SM, Kayano T, Yuan B, Nishiura H
Epidemics   27 123-131   Jun 2019   [Refereed]
During an Ebola virus disease (EVD) outbreak, the analysis and forecasting of the incidence in real time is challenged by reporting of cases, especially the reporting delay. It should be remembered that the latest count of cases is likely underest...
Akhmetzhanov AR, Asai Y, Nishiura H
Philosophical Transactions of the Royal Society B   374(1775) 20180268   May 2019   [Refereed][Invited]
Lassa fever (LF) is a zoonotic disease that is widespread in West Africa and involves animal-to-human and human-to-human transmission. Animal-to-human transmission occurs upon exposure to rodent excreta and secretions, i.e. urine and saliva, and h...
Akhmetzhanov AR, Lee H, Jung S, Kinoshita R, Shimizu K, Yoshi K, Nishiura H
PLoS Curr Outbreaks   1    2018   [Refereed]
Japan experienced a multi-generation outbreak of measles from March to May, 2018. The present study aimed to capture the transmission dynamics of measles by employing a simple mathematical model, and also forecast the future incidence of cases.
Shimizu K, Kinoshita R, Yoshi K, Akhmetzhanov AR, Jung S, Lee H, Nishiura H
Western Pac Surveill Response J   9(3)    2018   [Refereed]
We investigated a measles outbreak that spread to Japan and Taiwan, China during March–May 2018, exploring the characteristics of the super-spreading event.
Matsuyama R, Akhmetzhanov AR, Endo A, Lee H, Yamaguchi T, Tsuzuki S, Nishiura H
PeerJ   6 e4583   2018   [Refereed]
A Rohingya refugee camp in Cox’s Bazar, Bangladesh experienced a large-scale diphtheria epidemic in 2017. The background information of previously immune fraction among refugees cannot be explicitly estimated, and thus we conducted an uncertainty ...
Tsuzuki S, Lee H, Miura F, Chan YH, Jung S, Akhmetzhanov AR, Nishiura H
Eurosurveillance   22(46) 17-00710   2017   [Refereed]
While plague in Madagascar has been recognised as endemic for more than two decades, the country has experienced the largest ever observed epidemic of pneumonic plague in 2017 through human-to-human transmission. As of 31 October 2017, the cumulat...
Vasse M, Noble RJ, Akhmetzhanov AR, Torres-Barceló C, Gurney J, Benateau S, Gougat-Barbera C, Kaltz O, Hochberg ME
Proc Natl Acad Sci USA   114(3) 546-551   2017   [Refereed]
The evolution of cooperation is a central issue in biology and the social sciences. Study of model systems of social microbes has focused on how “cooperators” and “cheats” interact but rarely accounts for the surrounding environment. We demonstrat...
Akhmetzhanov AR, Hochberg ME
eLife   e06266   2015   [Refereed]
Grognard F, Akhmetzhanov AR, Bernard O
Automatica   50(2) 359-368   2014   [Refereed]
Akhmetzhanov AR, Grognard F, Mailleret L, Bernhard P
Annals of the International Society of Dynamic Games   12 73-95   2013   [Refereed][Invited]
In this contribution we consider a seasonal consumer–resource system and focus on the evolution of consumer behavior. It is assumed that consumer and resource individuals live and interact during seasons of fixed lengths separated by winter period...
Akhmetzhanov AR, Worden L, Dushoff J
Phys Rev E   88(1) 012816   2013   [Refereed]
Grognard F,Akhmetzhanov AR, Bernhard O
INRIA Internal Report   (7929)    Apr 2012   [Refereed]
Akhmetzhanov AR, Grognard F, Mailleret L
Evolution   65(11) 3113-3125   2011   [Refereed]
Bernhard P, Grognard F, Mailleret L, Akhmetzhanov AR
7314    Jun 2010   [Refereed]
Akhmetzhanov AR, Grognard F, Mailleret L, Bernhard P
INRIA Internal Report   7312    Jun 2010   [Refereed]
Grognard F, Akhmetzhanov AR, Bernard O, Masci P
Proceedings of the 49th IEEE Conference on Decision and Control, Atlanta GA, USA      2010   [Refereed]
We address the question of optimization of the biomass long term productivity in the framework of microalgal biomass production in photobioreactors under the influence of day/night cycles. For that, we propose a simple bioreactor model accounting ...
Akhmetzhanov AR
Annals of the International Society of Dynamic Games   10 1-13   2009   [Refereed]
Akhmetzhanov AR, Bernhard P, Grognard F, Mailleret L
Proceedings of International Conference on Game Theory for Networks GameNets’09, Istanbul, Turkey      2009   [Refereed]
In this work we investigate a (seasonal) prey-predator model where the system evolves during a season whose length is fixed. Predators have the choice between foraging the food (eating preys) and reproducing (laying eggs at a rate proportional to ...
Melikyan A, Olsder GJ, Akhmetzhanov AR
Int Game Theory Rev   10(4) 437-459   2008   [Refereed]
Saakian DB, Rozanova O, Akhmetzhanov AR
Phys Rev E   78(4) 041908   2008   [Refereed]
Melikyan A, Akhmetzhanov AR, Hovakimyan H
Syst Control Lett   56(11-12) 714-721   2007   [Refereed]
Akhmetzhanov AR, Melikyan AA, Fradkov AL
PMM-J Appl Math Mech   71(6) 809-818   2007   [Refereed]
Akhmetzhanov AR, Melikyan AA
PMM-J Appl Math Mech   71(2) 234-246   2007   [Refereed]
Melikyan AA, Akhmetzhanov AR, Hovakimyan N
American Control Conference, Proceedings of the 2005   2 865-869   2005   [Refereed]
Inverse Cauchy problem for a system of differential equations
Akhmetzhanov AR, Tarabanko Yu
Fundamental Problems of Basic and Applied Mathematics   4-9   2005   [Refereed]

Teaching Experience

  • Introduction to modelling (McMasterUniversity, Department of Mathematics and Statistics, Hamilton, Ontario, Canada)
  • Calculus I (Moscow Institute of Physics and Technology, Department of Mathematics)

Research Grants & Projects

Modeling of adaptation of plant pests
Agropolis Foundation, France: 
Project Year: Jul 2009 - Dec 2010    Investigator(s): Virginie Ravigne and Frederic Grognard (Co-PIs)
Singular characteristics of Hamilton-Jacobi equations belonging to the boundary domain
Russian Foundation for Basic Research: 
Project Year: 2007 - 2009    Investigator(s): Arik A. Melikyan (PI)
Analysis of capabilities of the control of a moving object under conflict and uncertainties
Russian Foundation for Basic Research: 
Project Year: 2005 - 2007    Investigator(s): Alexander I. Ovseevich (PI)
Development of the method of singular characteristics for multi-dimensional Hamilton-Jacobi equation
Russian Foundation for Basic Research: 
Project Year: 2004 - 2006    Investigator(s): Arik A. Melikyan (PI)
Control of linear systems with distributed parameters
Russian Foundation for Basic Research: 
Project Year: 2004 - 2006    Investigator(s): Alexander I. Egorov (PI)