Takumi Abe

J-GLOBAL         Last updated: Jan 7, 2020 at 22:30
 
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Name
Takumi Abe
E-mail
abe-thoku-iryo-u.ac.jp
Affiliation
Health Sciences University of Hokkaido
Section
Faculty of Pharmaceutical Sciences
Research funding number
80453273
ORCID ID
0000-0003-1729-1097

Research Areas

 
 

Published Papers

 
Takumi Abe, Yuta Kosaka, Miku Asano, Natsuki Harasawa, Akane Mishina, Misato Nagasue, Yuri Sugimoto, Kazuaki Katakawa, Shunsuke Sueki, Masahiro Anada, Koji Yamada
Organic Letters      Feb 2019   [Refereed]
Tomoki Itoh, Yuusuke Chiba, Shunsuke Kawaguchi, Yuki Koitaya, Yuuma Yoneta, Koji Yamada, Takumi Abe
RSC Advances   9(18) 10420   2019   [Refereed]
Takumi Abe, Koji Yamada, Syuhei Satake
HETEROCYCLES   99(0)    2019   [Refereed]
Journal of Synthetic Organic Chemistry Japan      Aug 2018   [Refereed]
Takumi Abe, Koji Yamada
Organic Letters      Mar 2018   [Refereed]
Takumi Abe, Haruka Shimizu, Shiori Takada, Takahiro Tanaka, Mai Yoshikawa, Koji Yamada
Organic Letters      Mar 2018   [Refereed]
Takumi Abe, Masaru Terasaki
Helvetica Chimica Acta   101(2) e1700284   Jan 2018   [Refereed]
Takumi Abe, Tsuyoshi Morita, Koji Yamada
HETEROCYCLES   97(0)    2018   [Refereed]
Takumi Abe, Koji Yamada, Tomohiro Haruyama
Synthesis      Sep 2017   [Refereed]
Takumi Abe, Takuro Suzuki, Masahiro Anada, Shigeki Matsunaga, Koji Yamada
Organic Letters      Aug 2017   [Refereed]
Takumi Abe, Koji Yamada
Journal of Natural Products      Feb 2017   [Refereed]
Takumi Abe, Yuka Takahashi, Yuki Matsubara, Koji Yamada
Org. Chem. Front.      2017   [Refereed]
Takumi Abe, Koshiro Kida, Koji Yamada
Chem. Commun.      2017   [Refereed]
Takashi Nishiyama, Noriyuki Hatae, Teruki Yoshimura, Sawa Takaki, Takumi Abe, Minoru Ishikura, Satoshi Hibino, Tominari Choshi
European Journal of Medicinal Chemistry   121 561   Oct 2016   [Refereed]
Tomoki Itoh, Takumi Abe, Tominari Choshi, Takashi Nishiyama, Reiko Yanada, Minoru Ishikura
European Journal of Organic Chemistry   2016 2290-2299   May 2016
Copyright © 2016 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim. Concise syntheses of 9-methoxyellipticine, 3,4-dihydroellipticine (μ-alkaloid D), 1,2,3,4-tetrahydroellipticine, 2-methyl-1,2,3,4-tetrahydroellipticine, olivacine, 3,4-dihydroolivacine, ...
Abe Takumi, Ishikura Minoru
Journal of Synthetic Organic Chemistry, Japan   74(2) 117-129   Jan 2016
In our continuing study of the reactivity and synthetic application of indolylborate as a versatile synthetic intermediate, we found that the use of indolylborate in palladium-catalyzed cross-coupling reaction is highly effective for the synthesis...
Itoh T, Abe T, Choshi T, Nishiyama T, Ishikura M.
Heterocycles   92(6) 1132-1136   2016   [Refereed]
Ishikura M, Abe T, Choshi T, Hibino S
Natural product reports      Jul 2015   [Refereed]
Tomoki Itoh, Takumi Abe, Shuhei Nakamura, Minoru Ishikura
Heterocycles   91 1423-1428   Jan 2015
A one-pot conversion of skatole to tryptanthrin, an indolo[2,1-b]quinazoline alkaloid, was achieved by Cu-mediated oxidation.
Takumi Abe, Minoru Ishikura
Heterocycles   90 673-680   Jan 2015
© 2015 The Japan Institute of Heterocyclic Chemistry. The palladium-catalyzed intramolecular oxidative coupling reaction of 1,1'-carbonyldiindoles was achieved by using Pd(OAc)2 and Cu(OAc)2, producing 1,1'-carbonyl-2,2'-biindolyls, which were the...
Takumi Abe, Tomoki Itoh, Tominari Choshi, Satoshi Hibino, Minoru Ishikura
Tetrahedron Letters   55 5268-5270   Sep 2014
© 2014 Elsevier Ltd. All rights reserved. A one-pot approach to indolo[2,1-b]quinazolines from indole-3-carbaldehydes through the Dakin oxidation was developed. It was shown that the reaction proceeded through the condensation of indole-3-carbalde...
Mami Fujii, Takashi Nishiyama, Tominari Choshi, Nanase Satsuki, Takaya Fujiwaki, Takumi Abe, Minoru Ishikura, Satoshi Hibino
Tetrahedron   70 1805-1810   Mar 2014
A novel one-pot synthesis of carbazole-1,4-quinone by consecutive Pd-catalyzed cyclocarbonylation, desilylation, and oxidation reactions is described. We propose a possible mechanism of the cyclocarbonylation reaction between 3-iodo-2-propenylindo...
Takumi Abe, Toshiaki Ikeda, Tomoki Itoh, Noriyuki Hatae, Eiko Toyota, Minoru Ishikura
Heterocycles   88 187-191   Jan 2014
A one-pot synthesis of 3,3'-bisindolylmethanes was developed through the intermolecular Pummerer reaction using indole as a nucleophile. © 2014 The Japan Institute of Heterocyclic Chemistry.
Noriyuki Hatae, Risa Satoh, Hitomi Chiba, Takahiro Osaki, Takashi Nishiyama, Minoru Ishikura, Takumi Abe, Satoshi Hibino, Tominari Choshi, Chiaki Okada, Eiko Toyota
Medicinal Chemistry Research   23 4956-4961   Jan 2014
© Springer Science+Business Media New York 2014. Calothrixin B, whose structure consists of a pentacyclic indolo[3,2-j]phenanthridine framework, was originally isolated as a secondary metabolite from Calothrix cyanobacteria and was found to exhibi...
Hatae N, Nakamura J, Okujima T, Ishikura M, Abe T, Hibino S, Choshi T, Okada C, Yamada H, Uno H, Toyota E
Bioorganic & medicinal chemistry letters   23(16) 4637-4640   Aug 2013   [Refereed]
Takumi Abe
Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry   71 62-63   Jul 2013
The development of biomimetic reactions is one of the major challenges for synthetic chemists, because mimicking these complicated reactions in the laboratory by simple catalytic systems is difficult to achieve in general. Vitamine B6-dependent am...
Abe T, Nakamura S, Yanada R, Choshi T, Hibino S, Ishikura M
Organic letters   15(14) 3622-3625   Jul 2013   [Refereed]
Ishikura M, Abe T, Choshi T, Hibino S
Natural product reports   30(5) 694-752   May 2013   [Refereed]
ABE Takumi
J. Synth. Org. Chem. Jpn.   71(1) 62-63   Jan 2013
The development of biomimetic reactions is one of the major challenges for synthetic chemists, because mimicking these complicated reactions in the laboratory by simple catalytic systems is difficult to achieve in general. Vitamine B6-dependent am...
阿部 匠
薬学雑誌   133(1) 99-106   2013
Abe Takumi
YAKUGAKU ZASSHI   133(1) 99-106   2013
  This review describes a synthesis of indole compounds using multifunctional synthons. The multifunctional synthons, trienes and gramines, were respectively synthesized using Pd-catalyzed tandem cyclization/cross-coupling reaction of indolylborat...
Ishikura M, Yamada K, Abe T
Natural product reports   27(11) 1630-1680   Nov 2010   [Refereed]
Takumi Abe, Hiroyuki Komatsu, Toshiaki Ikeda, Noriyuki Hatae, Eiko Toyota, Minoru Ishikura
Heterocycles   86 505-513   Dec 2012
A short total synthesis of a bisindole alkaloid, yuechukene, was achieved through the dimerization of β-dehydroprenylindole generated in situ from 1-(indol-3-yl)-3-methylbut-2-en-1-amine. © 2012 The Japan Institute of Heterocyclic Chemistry.
Takumi Abe, Hiroyuki Takeda, Yumi Takahashi, Yoshihisa Miwa, Koji Yamada, Minora Ishikura
European Journal of Organic Chemistry   2010(17) 3281-3294   Jun 2010   [Refereed]
Cu- and Rh-catalyzed coupling reactions of 2-azabicyclo[2.2.1]hept-5-en-3- ones (1) with arylboronic acids were successful carried out under microwave irradiation conditions and yielded N-aryl and C-aryl derivatives of 1, respectively. © 2010 Wile...
Takumi Abe, Toshiaki Ikeda, Tominari Choshi, Satoshi Hibino, Noriyuki Hatae, Eiko Toyata, Reiko Yanada, Minoru Ishikura
European Journal of Organic Chemistry   5018-5027   Sep 2012
The palladium-catalyzed tandem cyclization/cross-coupling reaction of triethyl(indol-2-yl)borate with vinyl bromide was successfully used in the concise total synthesis of the indolophenanthridine alkaloids, calothrixins A and B. Palladium-catalyz...
Matsumoto K, Choshi T, Hourai M, Zamami Y, Sasaki K, Abe T, Ishikura M, Hatae N, Iwamura T, Tohyama S, Nobuhiro J, Hibino S
Bioorganic & medicinal chemistry letters   22(14) 4762-4764   Jul 2012   [Refereed]
Lowery CA, Abe T, Park J, Eubanks LM, Sawada D, Kaufmann GF, Janda KD
Journal of the American Chemical Society   131(43) 15584-15585   Nov 2009   [Refereed]
Abe T, Ikeda T, Yanada R, Ishikura M
Organic letters   13(13) 3356-3359   Jul 2011   [Refereed]
Koji Yamada, Yuichi Namerikawa, Takumi Abe, Minoru Ishikura
Heterocycles   77(2) 825-828   Feb 2009   [Refereed]
The reaction of Nβ-benzylserotonin with α,β-unsaturated and aryl aldehydes in the presence of a base produced 1H-azepino[5,4,3-cd]indoles. © 2009 The Japan Institute of Heterocyclic Chemistry All rights reserved.
Koji Yamada, Sayaka Yamaguchi, Noriyuki Hatae, Takumi Abe, Tatsunori Iwamura, Minoru Ishikura
Heterocycles   83 815-826   Mar 2011
A novel and simple protocol for the synthesis of 1-(2-aminoethyl)- pyrano[3,2-e]indole derivatives has been developed using the Pictet-Spengler reaction of Nb-benzylserotonin with αβ-unsaturated aldehydes in the presence of Et3N in 2-propanol or M...
Takumi Abe, Hiroyuki Takeda, Yumi Takahashi, Yoshihisa Miwa, Koji Yamada, Minoru Ishikura
Heterocycles   75(12) 2931-2936   Dec 2008   [Refereed]
Rhodium-catalyzed arylation of 2-azabicyclo[2.2.1]hept-5-en-3-one was successfully performed by applying microwave irradiation. © 2008 The Japan Institute of Heterocyclic Chemistry.