安部公博 (Kimihiro Abe) - マイポータル

基本情報

所属: 国立感染症研究所主任研究官

学位: 理学博士(筑波大学大学院)

研究者番号: 10748940
J-GLOBAL ID: 201801003875384020
researchmap会員ID: B000301753

研究分野

論文

Periodontal pathogen-derived extracellular vesicles promote EGFR-dependent malignant traits in human pancreatic cancer cells

Takehiro Yamaguchi, Ryoma Nakao, Masayuki Shiota, Kimihiro Abe, Yukihiro Akeda

bioRxiv 2026年1月29日
Intranasal vaccination with probiotic Escherichia coli membrane vesicles displaying pneumococcal capsular polysaccharides elicits mucosal immunity

Ryoma Nakao, Soichiro Kimura, Kimihiro Abe, Takehiro Yamaguchi, Eisuke Kuroda, Shigeto Hamaguchi, Kazuhiro Tateda, Yukino Ohki, Naoki Narisawa, Makoto Ohnishi …

11(1) 23-23 2025年12月23日査読有り
Assessment of periodontitis vaccine using three different bacterial outer membrane vesicles in canine model

Ryoma Nakao, Takehiro Yamaguchi, Haruka Shibasaki, Jun Saeki, Aoi Takahashi, Ryunosuke Tominaga, Kimihiro Abe, Yukihiro Akeda, Tomoyo Nakagawa-Nakamura, Tomohiko Nishino …

mSphere 10(4) e0103324 2025年3月査読有り
A Simple and Cost-effective Transformation System for Porphyromonas gingivalis via Natural Competence

Kimihiro Abe, Hiroko Yahara, Ryoma Nakao, Takehiro Yamaguchi, Yukihiro Akeda

Frontiers in Microbiology 15 1476171 2024年10月査読有り筆頭著者責任著者
Mucosal adjuvanticity and mucosal booster effect of colibactin-depleted probiotic Escherichia coli membrane vesicles

Hiroki Uchiyama, Toshifumi Kudo, Takehiro Yamaguchi, Nozomu Obana, Kenji Watanabe, Kimihiro Abe, Hidetaka Miyazaki, Masanori Toyofuku, Nobuhiko Nomura, Yukihiro Akeda …

Human Vaccines; Immunotherapeutics 20(1) 2024年4月24日査読有り
Identification of CgeA as a glycoprotein that anchors polysaccharides to the spore surface in Bacillus subtilis

Yusei Nakaya, Miu Uchiike, Mayuko Hattori, Momoka Moriyama, Kimihiro Abe, Ella Kim, Patrick Eichenberger, Daisuke Imamura, Tsutomu Sato

Molecular Microbiology 2023年7月査読有り
Visualization and characterization of spore morphogenesis in Paenibacillus polymyxa ATCC39564

Kimihiro Abe, Hiroko Kato, Yuta Hasegawa, Tatsuya Yamamoto, Nobuhiko Nomura, Nozomu Obana

The Journal of General and Applied Microbiology 68(2) 79-86 2022年4月査読有り筆頭著者
Membrane vesicles derived from Clostridium botulinum and related clostridial species induce innate immune responses via MyD88/TRIF signaling in vitro

Nobuhide Kobayashi, Kimihiro Abe, Sachiyo Akagi, Mayu Kitamura, Yoshitake Shiraishi, Aki Yamaguchi, Masahiro Yutani, Sho Amatsu, Takuhiro Matsumura, Nobuhiko Nomura …

Frontiers in Microbiology 13 720308 2022年2月査読有り
Extreme C-terminal element of SprA serine integrase is a potential component of the “molecular toggle switch” which controls the recombination and its directionality

Kimihiro Abe, Takumi Takahashi, Tsutomu Sato

Molecular Microbiology 115(6) 1110-1121 2021年6月査読有り筆頭著者責任著者
Autolysis-mediated membrane vesicle formation in Bacillus subtilis

Kimihiro Abe, Masanori Toyofuku, Nobuhiko Nomura, Nozomu Obana

Environmental Microbiology 23(5) 2632-2647 2021年5月査読有り筆頭著者
Biofilms: hot spots of horizontal gene transfer (HGT) in aquatic environments, with a focus on a new HGT mechanism

Kimihiro Abe, Nobuhiko Nomura, Satoru Suzuki

FEMS Microbiology Ecology 96(5) fiaa031 2020年5月1日査読有り筆頭著者
Compatibility of site-specific recombination (SSR) units between mobile genetic elements

Shota Suzuki, Miki Yoshikawa, Daisuke Imamura, Kimihiro Abe, Patrick Eichenberger, Tsutomu Sato

iScience 23(1) 100805-100805 2020年1月査読有り
Expansion of the spore surface polysaccharide layer in Bacillus subtilis by deletion of genes encoding glycosyltransferases and glucose modification enzymes

Bentley Shuster, Mark Khemmani, Yusei Nakaya, Gudrun Holland, Keito Iwamoto, Kimihiro Abe, Daisuke Imamura, Nina Maryn, Adam Driks, Tsutomu Sato …

Journal of Bacteriology 201(19) e00321-19 2019年9月査読有り
Bacillus subtilis YlxR, which is involved in glucose-responsive metabolic changes, regulates expression of tsaD for protein quality control of pyruvate dehydrogenase

Mitsuo Ogura, Tsutomu Sato, Kimihiro Abe

Frontiers in Microbiology 10 923 2019年5月査読有り
Contributions of crust proteins to spore surface properties in Bacillus subtilis

Bentley Shuster, Mark Khemmani, Kimihiro Abe, Xiaoyu Huang, Yusei Nakaya, Nina Maryn, Sally Buttar, Adriana N. Gonzalez, Adam Driks, Tsutomu Sato …

Molecular Microbiology 111(3) 825-843 2019年3月査読有り
A novel non prophage(-like) gene-intervening element within gerE that is reconstituted during sporulation in Bacillus cereus ATCC10987

Kimihiro Abe, Shin-ya Shimizu, Shuhei Tsuda, Tsutomu Sato

Scientific Reports 7(1) 11426 2017年9月査読有り筆頭著者
Mechanism of bacterial gene rearrangement: SprA-catalyzed precise DNA recombination and its directionality control by SprB ensure the gene rearrangement and stable expression of spsM during sporulation in Bacillus subtilis

Kimihiro Abe, Takuo Takamatsu, Tsutomu Sato

Nucleic Acids Research 45(11) 6669-6683 2017年6月査読有り筆頭著者
Developmentally-Regulated Excision of the SPβ Prophage Reconstitutes a Gene Required for Spore Envelope Maturation in Bacillus subtilis

Kimihiro Abe, Yuta Kawano, Keito Iwamoto, Kenji Arai, Yuki Maruyama, Patrick Eichenberger, Tsutomu Sato

PLoS Genetics 10(10) e1004636 2014年10月9日査読有り筆頭著者
Regulated DNA rearrangement during sporulation in Bacillus weihenstephanensis KBAB4

Kimihiro Abe, Akira Yoshinari, Takahiro Aoyagi, Yasunori Hirota, Keito Iwamoto, Tsutomu Sato

Molecular Microbiology 90(2) 415-427 2013年10月査読有り筆頭著者
Stabilization of Clostridium perfringens collagenase mRNA by VR-RNA-dependent cleavage in 5' leader sequence

Nozomu Obana, Yu Shirahama, Kimihiro Abe, Kouji Nakamura

Molecular Microbiology 77(6) 1416-1428 2010年9月査読有り

もっとみる

MISC

生きた細胞のゲノムを切り貼りする

安部公博

生物工学 98(6) 315-315 2020年招待有り筆頭著者責任著者

共同研究・競争的資金等の研究課題

Bacillus属細菌由来ナノ粒子を抗原担体としたワクチン開発

日本学術振興会科学研究費助成事業基盤研究(C) 2022年4月 - 2025年3月

安部公博
歯周病原細菌外膜小胞に含まれるsRNAの生体内挙動と病態形成における意義

日本学術振興会科学研究費助成事業国際共同研究加速基金(国際共同研究強化(B)) 2021年10月 - 2025年3月

中尾龍馬, Lee Seohyun, 矢原寛子, 安部公博
in vivoゲノム記録法による微生物集団の解析

日本学術振興会科学研究費助成事業基盤研究(C) 2019年4月 - 2023年3月

安部公博
枯草菌胞子を用いた有用多糖類合成系の確立に向けての基礎研究

日本学術振興会科学研究費助成事業若手研究(B) 2015年4月 - 2018年3月

安部公博

安部公博

基本情報

研究分野

論文

MISC

共同研究・競争的資金等の研究課題

メニュー

共著者の一覧