Kenta Horie

Profile Information

Affiliation: Assistant professor, Institute for Advanced Academic Research / Graduate School of Medicine Department of Artificial intelligence medicine, Chiba University

Researcher number: 90983528
ORCID iD: https://orcid.org/0000-0003-4175-1014
J-GLOBAL ID: 202301003799070968
researchmap Member ID: R000050162

Research Interests

Research Areas

Research History

Apr, 2023 - Present

Visiting Researcher, RIKEN Center for Integrative Medical Sciences, RIKEN
Apr, 2023 - Present

Project Assistant Professor, Department of Artificial Intelligence Medicine, Graduate School of Medicine, Chiba University
Apr, 2023 - Present

Project Assistant Professor, Institute for Advanced Academic Research (IAAR), Chiba University
Apr, 2021 - Mar, 2023

DC2 (Research Fellowship for Young Scientists), Japan Society for the Promotion of Science

Education

Apr, 2020 - Mar, 2023

Department of Pharmaceutical Sciences, Graduate School of Pharmaceutical Sciences, The University of Tokyo
Apr, 2018 - Mar, 2020

Department of Pharmaceutical Sciences, Graduate School of Pharmaceutical Sciences, The University of Tokyo
Apr, 2014 - Mar, 2018

Department of Medicinal and Life Science, Faculty of Pharmaceutical Sciences, Tokyo University of Science

Awards

Dec, 2022

Best Presentation Award, The 51st Annual Meeting of the Japanese Society for Immunology, Japanese Society for Immunology

Papers

Neutrophil adhesion to vessel walls impairs pulmonary circulation in COVID-19 pathology

Yoshihiro Kawaoka, Hiroshi Ueki, I-Hsuan Wang, Maki Kiso, Kenta Horie, Shun Iida, Sohtaro Mine, Michiko Ujie, Hung-Wei Hsu, Chen-Hui Henry …

Feb 7, 2024
Mitochondrial protein C15ORF48 is a stress-independent inducer of autophagy that regulates oxidative stress and autoimmunity

Yuki Takakura, Moeka Machida, Natsumi Terada, Yuka Katsumi, Seika Kawamura, Kenta Horie, Maki Miyauchi, Tatsuya Ishikawa, Nobuko Akiyama, Takao Seki …

Nature Communications, Feb 1, 2024 Peer-reviewed
Acute irradiation causes a long-term disturbance in the heterogeneity and gene expression profile of medullary thymic epithelial cells

Kenta Horie, Kano Namiki, Kyouhei Kinoshita, Maki Miyauchi, Tatsuya Ishikawa, Mio Hayama, Yuya Maruyama, Naho Hagiwara, Takahisa Miyao, Shigeo Murata …

Frontiers in Immunology, 14, Nov 2, 2023 Peer-reviewedLead author
T‐cell receptor repertoire analysis of CD4-positive T cells from blood and an affected organ in an autoimmune mouse model

Tatsuya Ishikawa, Kenta Horie, Yuki Takakura, Houko Ohki, Yuya Maruyama, Mio Hayama, Maki Miyauchi, Takahisa Miyao, Naho Hagiwara, Tetsuya J. Kobayashi …

Genes to Cells, Nov, 2023 Peer-reviewed
Pseudoirreversible inhibition elicits persistent efficacy of a sphigosine-1-phosphate receptor-1 antagonist

Yuya Maruyama, Yusuke Ohsawa, Takayuki Suzuki, Yuko Yamauchi, Kohsuke Ohno, Hitoshi Inoue, Akitoshi Yamamoto, Morimichi Hayashi, Yuji Okuhara, Wataru Muramatsu …

May 9, 2023
Sample Preparation and Integrative Data Analysis of a Droplet-based Single-Cell ATAC-sequencing Using Murine Thymic Epithelial Cells

Tatsuya Ishikawa, Hiroto Ishii, Takahisa Miyao, Kenta Horie, Maki Miyauchi, Nobuko Akiyama, Taishin Akiyama

BIO-PROTOCOL, 13, 2023 Peer-reviewed
Integrative analysis of scRNA-seq and scATAC-seq revealed transit-amplifying thymic epithelial cells expressing autoimmune regulator

Takahisa Miyao, Maki Miyauchi, S. Thomas Kelly, Tommy W Terooatea, Tatsuya Ishikawa, Eugene Oh, Sotaro Hirai, Kenta Horie, Yuki Takakura, Houko Ohki …

eLife, 11, May 17, 2022 Peer-reviewed
How does spaceflight affect the acquired immune system?

Taishin Akiyama, Kenta Horie, Eiichi Hinoi, Manami Hiraiwa, Akihisa Kato, Yoichi Maekawa, Akihisa Takahashi, Satoshi Furukawa

npj Microgravity, 6(1), May 7, 2020 Peer-reviewed
Impact of spaceflight on the murine thymus and mitigation by exposure to artificial gravity during spaceflight

Kenta Horie, Tamotsu Kato, Takashi Kudo, Hiroki Sasanuma, Maki Miyauchi, Nobuko Akiyama, Takahisa Miyao, Takao Seki, Tatsuya Ishikawa, Yuki Takakura …

Scientific Reports, 9(1), Dec 27, 2019 Peer-reviewedLead author
Down-regulation of GATA1-dependent erythrocyte-related genes in the spleens of mice exposed to a space travel

Kenta Horie, Hiroki Sasanuma, Takashi Kudo, Shin-ichiro Fujita, Maki Miyauchi, Takahisa Miyao, Takao Seki, Nobuko Akiyama, Yuki Takakura, Miki Shimbo …

Scientific Reports, 9(1), May 21, 2019 Peer-reviewedLead author
Long-term hindlimb unloading causes a preferential reduction of medullary thymic epithelial cells expressing autoimmune regulator (Aire).

Horie K, Takashi Kudo, Yoshinaga R, Akiyama N, Sasanuma H, Kobayashi TJ, Shimbo M, Jeon H, Miyao T, Miyauchi M …

Biochemical and biophysical research communications, Jun 1, 2018 Peer-reviewedLead author

Books and Other Publications

臨床免疫・アレルギー科

科学評論社, 2019

Professional Memberships

Apr, 2018 - Present

Japanese Society for Immunology

Research Projects

Functional analysis of Gene Desert as an enhancer reservoir in the establishment of cell lineage commitment and its diversity

Grants-in-Aid for Scientific Research, Fund for the Promotion of Joint International Research (International Collaborative Research), Japan Society for the Promotion of Science, Sep, 2023 - Mar, 2028
Impairment in cancer immune surveillance evoked by obesity-induced abnormalities in T cell selection

Grants-in-Aid for Scientific Research, Grant-in-Aid for Research Activity Start-up, Japan Society for the Promotion of Science, Aug, 2023 - Mar, 2025

Profile Information

Research Interests

Research Areas

Research History

Education

Awards

Papers

Books and Other Publications

Professional Memberships

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