ティクシエ アニエス 三田

The main research area of my laboratory is to develop advanced microsystems for in-vitro biological cells applications. In particular it concerns the development of platforms with integrated electronics, micro-fluidics and electrical and/or optical sensors. They can be used for multi-cells culture with the possibility of electrical sensing, stimulation or manipulation, chemical experiments guided by micro-fluidic channels, and optical investigation. These platforms are built to be at the interface between the biological cells and the external set-up. The purpose is to propose new techniques to study the electrical expression of cells, for better understanding of biological cells way of working, and how they interact together.
When this research activity began, from 2000, micro-fabrication was used to create simple bio-microsystems (Bio-MEMS) with simple functions like micro-electrodes for dielectrophoresis, electroporation or electro-fusion of biological cells. Then, more complex electrical elements, like matrix of micro-electrodes or sensors began to be integrated using two technologies: standard CMOS technology on silicon and SOI substrates, or Thin-Film-Transistors (TFT) technology on glass substrates.
Neurons, muscles and smell cells are among the cells which are analyzed.