ウリアアグステイヌスロベルト (Agustinus Robert Uria) - マイポータル

基本情報

所属: 北海道大学大学院薬学研究院

学位: Doctor (Dr. rer. nat.) Biology - Microbiology(2012年12月 The University of Bonn, Germany)

通称等の別名: Agus
研究者番号: 40889565
J-GLOBAL ID: 202001010812339062
researchmap会員ID: R000008586

外部リンク: https://orcid.org/0000-0002-9223-7464

研究キーワード

Metagenomics, Microbial Diversity, Natural Product Chemistry & Biosynthesis, Biocatalysts, Synthetic Biology

研究分野

ライフサイエンス / 薬系化学、創薬科学 / Natural product biosynthesis, Genome/metagenome mining, Biocatalysts, Marine microbial diversity with biopharmaceutical potential

経歴

2020年6月 - 現在

北海道大学
2017年5月 - 2020年5月

北海道大学, 薬学部
2015年2月 - 2017年4月

Indonesian Ministry of Marine Affairs and Fisheries, Research Center for Marine and Fisheries Product Processing and Biotechnology (Staff Researcher)
2013年2月 - 2015年1月

ETH Zurich - Swiss Federal Institute of Technology, Institute of Microbiology, Postdoctoral Research Associate (Postdoctoral Research Associate)

学歴

2007年10月 - 2012年12月

The University of Bonn, Kekulé Institute of Organic Chemistry and Biochemistry, Doctoral studies (Dr. rer. nat) Biology - Microbiology
2002年9月 - 2004年2月

Wageningen University, M.Sc Biotechnology - Cellular and Molecular Biotech
1994年9月 - 1999年7月

Sam Ratulangi University, Faculty of Fisheries and Marine Science, Undergraduate studies in Marine Science - Marine Biotechnology

受賞

2017年

JSPS Postdoctoral Research Fellowship at Hokkaido University (2017-2019) with Grants-in-Aid for JSPS Fellows (KAKENHI), Japan Society for the Promotion of Sciences (JSPS)

Host Researcher/Professor: Prof. Toshiyuki Wakimoto
2007年

DAAD Doctoral Scholarship at The University of Bonn (2007-2011), Investigating natural product biosynthesis in uncultivated symbiotic bacteria of marine sponges, Deutscher Akademischer Austausch Dienst (DAAD)

Supervisor: Prof. Joern Piel

主要な論文

Animal-associated marine Acidobacteria with a rich natural-product repertoire

Stefan Leopold-Messer, Clara Chepkirui, Mathijs F.J. Mabesoone, Joshua Meyer, Lucas Paoli, Shinichi Sunagawa, Agustinus R. Uria, Toshiyuki Wakimoto, Jörn Piel

Chem (a Cell Press journal) 2023年12月査読有り
Ascidian-associated photosymbionts from Manado, Indonesia: secondary metabolites, bioactivity simulation, and biosynthetic insight

Inneke F. M. Rumengan, Vera I. Y. Roring, Jabal R. Haedar, Mayse S. Siby, Aldian H. Luntungan, Beivy J. Kolondam, Agustinus R. Uria, Toshiyuki Wakimoto

Symbiosis (Springer) 84(1) 71-82 2021年4月22日査読有り
Biosynthetic insights of calyculin- and misakinolide-type compounds in “Candidatus Entotheonella sp.”

Agustinus R. Uria, Jörn Piel, Toshiyuki Wakimoto

Methods in Enzymology (Elsevier) 604 287-330 2018年1月1日査読有り筆頭著者責任著者
An Unusual Flavin-Dependent Halogenase from the Metagenome of the Marine Sponge Theonella swinhoei WA

Duncan R.M. Smith, Agustinus R. Uria, Eric J.N. Helfrich, Daniela Milbredt, Karl Heinz Van Pée, Jörn Piel, Rebecca J.M. Goss

ACS Chemical Biology 12(5) 1281-1287 2017年5月19日査読有り
Metagenomics-guided mining of commercially useful biocatalysts from marine microorganisms

A.R. Uria, D.S. Zilda

Advances in Food and Nutrition Research (Elsevier) 78 1-26 2016年査読有り招待有り筆頭著者責任著者
Capturing natural product biosynthetic pathways from uncultivated symbiotic bacteria of marine sponges through metagenome mining: a mini-review

Agustinus R. Uria

Squalen Bulletin of Marine and Fisheries Postharvest and Biotechnology 2015年10月13日査読有り責任著者
Metabolic and evolutionary origin of actin-binding polyketides from diverse organisms

Reiko Ueoka, Agustinus R. Uria, Silke Reiter, Tetsushi Mori, Petra Karbaum, Eike E. Peters, Eric J.N. Helfrich, Brandon I. Morinaka, Muriel Gugger, Haruko Takeyama …

Nature Chemical Biology 11(9) 705-712 2015年9月20日査読有り筆頭著者
An environmental bacterial taxon with a large and distinct metabolic repertoire

Micheal C. Wilson, Tetsushi Mori, Christian Rückert, Agustinus R. Uria, Maximilian J. Helf, Kentaro Takada, Christine Gernert, Ursula A.E. Steffens, Nina Heycke, Susanne Schmitt …

NATURE (Nature Publishing Group) 506(7486) 58-62 2014年査読有り
Investigating natural product biosynthesis in uncultivated symbiotic bacteria of the marine sponge Theonella swinhoei

Agustinus Robert Uria

Doctoral Dissertation, Rheinische Friedrich-Wilhelms-Universität Bonn (Advisor: Joern Piel) 2013年
Metagenome mining reveals polytheonamides as posttranslationally modified ribosomal peptides

Michael F. Freeman, Cristian Gurgui, Maximilian J. Helf, Brandon I. Morinaka, Agustinus R. Uria, Neil J. Oldham, Hans Georg Sahl, Shigeki Matsunaga, Jörn Piel

SCIENCE (AAAS) 338(6105) 387-390 2012年10月19日査読有り
Cultivation-independent approaches to investigate the chemistry of marine symbiotic bacteria

Agustinus Uria, Jörn Piel

Phytochemistry Reviews (Springer) 8(2) 401-414 2009年6月査読有り招待有り
Production and characterization of a thermostable alcohol dehydrogenase that belongs to the aldo-keto reductase superfamily

Ronnie Machielsen, Agustinus R. Uria, Servé W.M. Kengen, John Van Der Oost

Applied and Environmental Microbiology (ASM) 72(1) 233-238 2006年1月査読有り

もっとみる

講演・口頭発表等

Bacterial symbionts in coral reef ecosystems: biotechnological potential for drug discovery

International Conference on Sustainable Coral Reefs: Science, Conservation, Resilience and Development 2024年12月13日招待有り
unique biocatalyst from a deep-sea sponge metagenome

Joint Hokkaido-Melbourne Workshop, Faculty of Pharmaceutical Sciences, Hokkaido University 2024年11月6日
Biochemical characterization of a novel enzyme from a deep-sea sponge metagenome

Piel Lab Reunion Symposium (virtual), ETH Zurich 2023年7月7日
Potential of biosynthetic pathways and biocatalysts from marine metagenomes for the smart eco-bioproduction of highly valuable compounds

SemNasHas XII (National Seminar), Faculty of Agriculture, Gadjah Mada University (UGM) 2022年10月22日招待有り
Sustainable use of biodiversity for drug discovery: accessing biosynthetic genes in microbial symbionts of marine sponges

2nd Wallacea International Webinar for Biotechnology & Conservation, Sam Ratulangi University 2021年11月18日招待有り
Marine microbial natural products with unusual building blocks: discovery of their biosynthetic machineries as a basis for drug development

A.R. Uria, T. Wakimoto

11th International Seminar of Indonesian Society for Microbiology: Microbiology contributions to humanity during and post Covid-19 pandemic 2021年11月16日招待有り
Understanding natural product biosynthesis in uncultivated marine bacteria towards the development of sustainable production systems

Webinar Nasional Kefarmasian (Pharmacy National Webinar) organized by Malahayati University 2020年11月20日招待有り
When metagenomics meets synthetic biology: new opportunities and potential applications in the digital era.

Uria, A.R.

International Webinar of Mathematics, Natural Sciences, and Learning in the New Normal Order - IWMANSELEN 2020 2020年10月15日招待有り
Biosynthetic potential of rare marine bacteria isolated from Okinawan sponges

Uria A.R, Haedar J.R, Jomori T, Matsuda K, Wakimoto T

The 12th Marine Biotechnology Conference held in Shizuoka 2019年9月11日
Investigating spongistatin biosynthesis in complex sponge-bacteria association

Uria, A.R, Matsuda K, Wakimoto, T

The 3rd International Symposium on Sponge Microbiology (ISSM), Shanghai (China) 2018年10月27日招待有り
Investigating natural product biosynthesis in complex marine sponge-bacteria association

Uria A.R, Matsuda K, Wakimoto T

Young Researchers Symposium on Redesigning Biosynthetic Machineries, Otaki (Japan) 2018年5月25日招待有り
Investigating natural product biosynthetic pathways in highly complex symbiotic bacterial assemblages of marine sponges

The 2nd International Microbial Biotechnology (IMBC2) at Atma Jaya Catholic University of Indonesia, Jakarta, November 15-16, 2016 2016年10月16日招待有り
Investigating the biosynthetic pathways of defensive compounds in uncultured microbiome of marine sponges

The 6th Indonesian Biotechnology Conference (IBC IV): “Enhancing industrial competitiveness through biotechnology innovation”, in Solo, Surakarta, September 6-8, 2016, organized by Indonesian Biotechnology Consortium. 2016年9月8日招待有り
Phylogeny-guided identification of type I polyketide synthase in uncultured microbiome of a marine sponge from Kapoposang Island

N.M. Kurnia, Y. Kusnadi, L. Dinawati, D.S. Zilda, Tri A. Hadi, S. Setyahadi, F. Felix, A.R. Uria

ASEAN Microbial Biotechnology Conference held in Bali on August 3-4, 2016 2016年7月4日
Revealing the biosynthetic capacity of uncultured symbiotic bacteria

A.R. Uria, C. Ruckert, J. Kalinowksi, S. Matsunaga, J. Piel

International VAAM Workshop on Sept. 28-30, 2011 in Bonn, Germany 2011年9月28日
Analyzing the drug potential of uncultivated symbionts of the sponge Theonella swinhoei

BMBF GenBioCom cluster-meeting in Freudenstadt-Lauterbad, Schwarzwald, Germany, on October 21-22, 2010. 2010年10月22日
Biosynthesis of the antitumor polyketide misakinolide A by an uncultivated symbiont of the marine sponge Theonella swinhoei

A.R. Uria, S. Matsunaga, J. Piel

VAAM symposium on symbiotic interaction, on October 7-8, 2010 at Wurzburg University, Germany 2010年10月7日
Insights into the secondary metabolism of an unusual uncultured symbiont of marine sponges

Die 39. Doktorandenworkshop, Naturstoffe: Chemie, Biologie und Okologie in Jena, Germany, April 16, 2010 2010年4月16日招待有り
Insight into the secondary metabolism of Entotheonella sp., an uncultivated symbiont of marine sponges

A.R. Uria, S. Matsunaga, and J. Piel

Die 22. Irseer Naturstofftage, Aktuelle Entwicklungen in der Naturstoff-Forschung, February 22-24, 2010 in Irsee, Germany 2010年2月24日

担当経験のある科目(授業)

所属学協会

共同研究・競争的資金等の研究課題

Investigating natural product biosynthetic pathways in the microbiomes associated with long-lived aquatic vertebrates

日本学術振興会科学研究費助成事業基盤研究(C) 基盤研究(C) 2021年7月 - 2024年3月
海綿動物由来医薬品資源の生合成研究

日本学術振興会科学研究費助成事業特別研究員奨励費 2017年7月 - 2019年3月

脇本敏幸, URIA AGUSTINUS

産業財産権

US Patent US-2014234903-A1 Biosynthetic gene cluster for the production of peptid/protein analogues

Piel, J, Gurgui, C, Freeman, M.F, Uria, A.R, Helf, M.J

社会貢献活動

What inspired me to pursue a career in science?

講師

Japan Society for the Promotion of Science (JSPS), and Akebi Secondary School in Noboribetsu, Hokkaido Science Dialogue Program 2018年7月9日

ウリアアグステイヌスロベルト

基本情報

研究キーワード

研究分野

経歴

学歴

受賞

主要な論文

講演・口頭発表等

担当経験のある科目(授業)

所属学協会

共同研究・競争的資金等の研究課題

産業財産権

社会貢献活動

メニュー

共著者の一覧