Masaru Akehi - My portal

Profile Information

Affiliation: Assistant Professor, Okayama University

J-GLOBAL ID: 201901008407768538
researchmap Member ID: B000375183

Papers

Novel Self-Forming Nanosized DDS Particles for BNCT: Utilizing A Hydrophobic Boron Cluster and Its Molecular Glue Effect

Abdul Basith Fithroni, Kazuko Kobayashi, Hirotaka Uji, Manabu Ishimoto, Masaru Akehi, Takashi Ohtsuki, Eiji Matsuura

Cells, 11(20) 3307-3307, Oct 21, 2022 Peer-reviewed
Teratogenicity and Fetal-Transfer Assessment of the Retinoid X Receptor Agonist Bexarotene.

Yuta Takamura, Izumi Kato, Manami Fujita-Takahashi, Midori Azuma-Nishii, Masaki Watanabe, Rui Nozaki, Masaru Akehi, Takanori Sasaki, Hiroyuki Hirano, Hiroki Kakuta

ACS pharmacology & translational science, 5(9) 811-818, Sep 9, 2022
A Novel Zr-89-labeled DDS Device Utilizing Human IgG Variant (scFv): "Lactosome" Nanoparticle-Based Theranostics for PET Imaging and Targeted Therapy

Melissa Siaw Han Lim, Takashi Ohtsuki, Fumiaki Takenaka, Kazuko Kobayashi, Masaru Akehi, Hirotaka Uji, Hirotsugu Kobuchi, Takanori Sasaki, Eiichi Ozeki, Eiji Matsuura

LIFE-BASEL, 11(2), Feb, 2021
Novel single-chain variant of antibody against mesothelin established by phage library

Hiromasa Yakushiji, Kazuko Kobayashi, Fumiaki Takenaka, Yoshiro Kishi, Midori Shinohara, Masaru Akehi, Takanori Sasaki, Eiji Ohno, Eiji Matsuura

CANCER SCIENCE, 110(9) 2722-2733, Sep, 2019
F-containing retinoid X receptor (RXR) partial agonist F-CBt-PMN whose tissue transferability is affected by coadministration of another RXR ligand

Yuta Takamura, Osamu Shibahara, Masaki Watanabe, Michiko Fujihara, Masaru Akehi, Takanori Sasaki, Hiroki Kakuta

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 258, Aug, 2019
Fluorine-18 (F-18)-labeled retinoid x receptor (RXR) partial agonist whose tissue transferability is affected by other RXR ligands

Yuta Takamura, Osamu Shibahara, Masaki Watanabe, Michiko Fujihara, Shoya Yamada, Masaru Akehi, Takanori Sasaki, Hiroyuki Hirano, Hiroki Kakuta

BIOORGANIC & MEDICINAL CHEMISTRY, 27(14) 3128-3134, Jul, 2019
Synthesis of C-11-Labeled RXR Partial Agonist 1-[(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)amino]benzotriazole-5-carboxylic Acid (CBt-PMN) by Direct [C-11]Carbon Dioxide Fixation via Organolithiation of Trialkyltin Precursor and PET Imaging Thereof (vol 60, pg 7139 , 2017)

Osamu Shibahara, Masaki Watanabe, Yuta Takamura, Shoya Yamada, Masaru Akehi, Takanori Sasaki, Akiya Akahoshi, Takahisa Hanada, Hiroyuki Hirano, Shunsuke Nakatani, Hiromi Nishioka, Yasuo Takeuchi, Hiroki Kakuta

JOURNAL OF MEDICINAL CHEMISTRY, 62(9) 4780-4781, May, 2019
Novel human anti-mesothelin scFv for cancer targeted therapy

Hiromasa Yakushiji, Kazuko Kobayashi, Fumiaki Takenaka, Masaru Akehi, Eiji Ohno, Eiji Matsuura

CANCER SCIENCE, 109 549-549, Dec, 2018
Anti-high Mobility Group Box 1 Antibody Ameliorates Albuminuria in MRL/lpr Lupus-Prone Mice

Haruki Watanabe, Katsue S. Watanabe, Keyue Liu, Sumie Hiramatsu, Sonia Zeggar, Eri Katsuyama, Noriko Tatebe, Akiya Akahoshi, Fumiaki Takenaka, Takahisa Hanada, Masaru Akehi, Takanori Sasaki, Ken-ei Sada, Eiji Matsuura, Masahiro Nishibori, Jun Wada

MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT, 6 31-39, Sep, 2017
Synthesis of C-11-Labeled RXR Partial Agonist 14(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)aminoThenzotriazole-5-carboxylic Acid (CBt-PMN) by Direct [C-11]Carbon Dioxide Fixation via Organolithiation of Trialkyltin Precursor and PET Imaging Thereof

Osamu Shibahara, Masaki Watanabe, Shoya Yamada, Masaru Akehi, Takanori Sasaki, Akiya Akahoshi, Takahisa Hanada, Hiroyuki Hirano, Shunsuke Nakatani, Hiromi Nishioka, Yasuo Takeuchi, Hiroki Kakuta

JOURNAL OF MEDICINAL CHEMISTRY, 60(16) 7139-7145, Aug, 2017
Synthesis of 11C labeled RXR partial agonist CBt-PMN by [11C] carbon dioxide fixation via organolithiation of trialkyltin precursor and PET imaging thereof

Osamu Shibahara, Masaki Watanabe, Masaru Akehi, Takanori Sasaki, Takahisa Hanada, Akiya Akahoshi, Hiroyuki Hirano, Hiroki Kakuta

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 254, Aug, 2017
Evaluation of brain migration and therapeutic effects of novel RXR partial agonist CBt-PMN on cognitive impairment in mice

Toshiki Kobayashi, Osamu Shibahara, Masaki Watanabe, Shoya Yamada, Masaru Akehi, Takanori Sasaki, Takahisa Hanada, Akiya Akahoshi, Hiroyuki Hirano, Hiroki Kakuta

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 252, Aug, 2016
The Function of beta 2-glycoprotein I in Angiogenesis and Its in Vivo Distribution in Tumor Xenografts

Arum Tri Wahyuningsih, Lianhua Shen, Kazuko Kobayashi, Takanori Sasaki, Fumiaki Takenaka, Takahisa Hanada, Masaru Akehi, Akiya Akahoshi, Eiichi Ozeki, Eiji Ando, Eiji Matsuura

ACTA MEDICA OKAYAMA, 70(1) 13-24, Feb, 2016
Chiral 1-(1,3-dithian-2-yl) prop-2-en-1-ols: new scaffolds for enantiopure alpha-hydroxyaldehydes

Masaru Akehi, Mariko Kawamoto, Tadakatsu Mandai

TETRAHEDRON, 71(37) 6488-6498, Sep, 2015
Positron Emission Tomography to Elucidate Pharmacokinetic Differences of Regioisomeric Retinoid X Receptor Agonists

Toshiki Kobayashi, Yuki Furusawa, Shoya Yamada, Masaru Akehi, Fumiaki Takenaka, Takanori Sasaki, Akiya Akahoshi, Takahisa Hanada, Eiji Matsuura, Hiroyuki Hirano, Akihiro Tai, Hiroki Kakuta

ACS MEDICINAL CHEMISTRY LETTERS, 6(3) 334-338, Mar, 2015
Elucidation of the pharmacokinetic difference of regioisomeric retinoid X receptor agonists having an alkoxy group by PET imaging

Toshiki Kobayashi, Kohei Kawata, Mariko Nakayama, Yuki Furusawa, Shoya Yamada, Hiroyuki Hirano, Fumiaki Takenaka, Masaru Akehi, Takanori Sasaki, Eiji Matsuura, Akihiro Tai, Hiroki Kakuta

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 248, Aug, 2014
PETイメージングを用いたアルコキシ基を有するレチノイドX受容体アゴニストの体内動態解析

加来田博貴, 小林俊貴, 古沢優貴, 山田翔也, 竹中文章, 明日卓, 佐々木崇了, 松浦栄次, 田井章博

ビタミン, 88(4) 213-213, Apr, 2014
アルコキシ基を有するレチノイドX受容体アゴニストの位置異性体間における体内動態差の解明とその応用

小林俊貴, 古沢優貴, 山田翔也, 平野裕之, 竹中文章, 明日卓, 佐々木崇了, 松浦栄次, 田井章博, 加来田博貴

日本薬学会年会要旨集, 134年会(4) 81-81, Mar, 2014
KINETIC RESOLUTION OF SECONDARY ALCOHOLS BY CHIRAL DMAP DERIVATIVES PREPARED BY THE UGI MULTICOMPONENT REACTION

Hiroki Mandai, Shunsuke Irie, Masaru Akehi, Kazunobu Yuri, Masaaki Yoden, Koichi Mitsudo, Seiji Suga

HETEROCYCLES, 87(2) 329-340, Feb, 2013

Misc.

PETイメージングを用いたRXRパーシャルアゴニストCBt-PMNの脳移行性の評価

芝原理, 小林俊貴, 渡邊将貴, 西井緑, 明日卓, 佐々木崇了, 赤星彰也, 花田貴寿, 平野裕之, 加来田博貴

日本薬学会年会要旨集, 137年会(2) 118-118, Mar, 2017