Akinobu Matsumoto

Profile Information

Affiliation: Graduate School of Science, Nagoya University

Degree: 医学博士(九州大学)

J-GLOBAL ID: 201401032576982256
researchmap Member ID: B000241468

External link: http://ger.sub.jp/index.html

Research Interests

Research Areas

Research History

Jun, 2023 - Present

Graduate School of Science, Nagoya University
May, 2017 - May, 2023

Associate Professor, Medical Institute of Bioregulation, Kyushu University
Nov, 2014 - Mar, 2018

PREST researcher, JST
Apr, 2012 - Apr, 2017

Post-doctoral fellow, Beth Israel Deaconess Medical Center, Harvard Medical School
Apr, 2011 - Mar, 2012

Post-doctoral fellow, Medical Institute of Bioregulation, Kyushu University
Apr, 2007 - Mar, 2011

Ph.D. student, Medical Institute of Bioregulation, Kyushu University
Apr, 2005 - Mar, 2007

Medical Institute of Bioregulation, Kyushu University

Papers

Mechanistic dissection of premature translation termination induced by acidic residues-enriched nascent peptide

Yuhei Chadani, Takashi Kanamori, Tatsuya Niwa, Kazuya Ichihara, Keiichi I. Nakayama, Akinobu Matsumoto, Hideki Taguchi

Cell Reports, 42(12) 113569-113569, Dec, 2023
The ASC‐1 complex promotes translation initiation by scanning ribosomes

Yuki Kito, Akinobu Matsumoto, Kazuya Ichihara, Chisa Shiraishi, Ronghao Tang, Atsushi Hatano, Masaki Matsumoto, Peixun Han, Shintaro Iwasaki, Keiichi I Nakayama

The EMBO Journal, Apr 24, 2023
RPL3L-containing ribosomes determine translation elongation dynamics required for cardiac function.

Chisa Shiraishi, Akinobu Matsumoto, Kazuya Ichihara, Taishi Yamamoto, Takeshi Yokoyama, Taisuke Mizoo, Atsushi Hatano, Masaki Matsumoto, Yoshikazu Tanaka, Eriko Matsuura-Suzuki …

Nature communications, 14(1) 2131-2131, Apr 20, 2023
Identification of unannotated coding sequences and their physiological functions

Kazuya Ichihara, Keiichi I Nakayama, Akinobu Matsumoto

The Journal of Biochemistry, Aug 12, 2022
Spatiotemporal reprogramming of differentiated cells underlies regeneration and neoplasia in the intestinal epithelium.

Tsunaki Higa, Yasutaka Okita, Akinobu Matsumoto, Shogo Nakayama, Takeru Oka, Osamu Sugahara, Daisuke Koga, Shoichiro Takeishi, Hirokazu Nakatsumi, Naoki Hosen …

Nature communications, 13(1) 1500-1500, Mar 21, 2022
Kastor and Polluks polypeptides encoded by a single gene locus cooperatively regulate VDAC and spermatogenesis.

Shintaro Mise, Akinobu Matsumoto, Keisuke Shimada, Toshiaki Hosaka, Masatomo Takahashi, Kazuya Ichihara, Hideyuki Shimizu, Chisa Shiraishi, Daisuke Saito, Mikita Suyama …

Nature communications, 13(1) 1071-1071, Feb 28, 2022
A ubiquitin-like protein encoded by the "noncoding" RNA TINCR promotes keratinocyte proliferation and wound healing.

Akihiro Nita, Akinobu Matsumoto, Ronghao Tang, Chisa Shiraishi, Kazuya Ichihara, Daisuke Saito, Mikita Suyama, Tomoharu Yasuda, Gaku Tsuji, Masutaka Furue …

PLoS genetics, 17(8) e1009686, Aug, 2021
Combinatorial analysis of translation dynamics reveals eIF2 dependence of translation initiation at near-cognate codons.

Kazuya Ichihara, Akinobu Matsumoto, Hiroshi Nishida, Yuki Kito, Hideyuki Shimizu, Yuichi Shichino, Shintaro Iwasaki, Koshi Imami, Yasushi Ishihama, Keiichi I Nakayama

Nucleic acids research, 49(13) 7298-7317, Jul 21, 2021
The autism-related protein CHD8 contributes to the stemness and differentiation of mouse hematopoietic stem cells.

Akihiro Nita, Yoshiharu Muto, Yuta Katayama, Akinobu Matsumoto, Masaaki Nishiyama, Keiichi I Nakayama

Cell reports, 34(5) 108688-108688, Feb 2, 2021
A Lipid Bilayer Formed on a Hydrogel Bead for Single Ion Channel Recordings.

Minako Hirano, Daiki Yamamoto, Mami Asakura, Tohru Hayakawa, Shintaro Mise, Akinobu Matsumoto, Toru Ide

Micromachines, 11(12), Dec 1, 2020
Cell cycle-dependent localization of the proteasome to chromatin.

Yuki Kito, Masaki Matsumoto, Atsushi Hatano, Tomoyo Takami, Kiyotaka Oshikawa, Akinobu Matsumoto, Keiichi I Nakayama

Scientific reports, 10(1) 5801-5801, Apr 2, 2020 Peer-reviewed
Intragenic antagonistic roles of protein and circRNA in tumorigenesis.

Jlenia Guarnerio, Yang Zhang, Giulia Cheloni, Riccardo Panella, Jesse Mae Katon, Mark Simpson, Akinobu Matsumoto, Antonella Papa, Cristian Loretelli, Andreas Petri …

Cell research, 29(8) 628-640, Aug, 2019 Peer-reviewed
Hidden peptides encoded by putative noncoding RNAs

Akinobu Matsumoto, Keiichi I. Nakayama

Cell Structure and Function, 43(1) 75-83, 2018 Peer-reviewed
SPAR, a lncRNA encoded mTORC1 inhibitor

Akinobu Matsumoto, John G. Clohessy, Pier Paolo Pandolfi

CELL CYCLE, 16(9) 815-816, 2017 Peer-reviewed
mTORC1 and muscle regeneration are regulated by the LINC00961-encoded SPAR polypeptide

Akinobu Matsumoto, Alessandra Pasut, Masaki Matsumoto, Riu Yamashita, Jacqueline Fung, Emanuele Monteleone, Alan Saghatelian, Keiichi I. Nakayama, John G. Clohessy, Pier Paolo Pandolfi

NATURE, 541(7636) 228-+, Jan, 2017 Peer-reviewed
The pleiotropic role of non-coding genes in development and cancer

Alessandra Pasut, Akinobu Matsumoto, John G. Clohessy, Pier Paolo Pandolfi

CURRENT OPINION IN CELL BIOLOGY, 43 104-113, Dec, 2016 Peer-reviewed
Fbw7 Targets GATA3 through Cyclin-Dependent Kinase 2-Dependent Proteolysis and Contributes to Regulation of T-Cell Development

Kyoko Kitagawa, Kiyoshi Shibata, Akinobu Matsumoto, Masaki Matsumoto, Tatsuya Ohhata, Keiichi I. Nakayama, Hiroyuki Niida, Masatoshi Kitagawa

MOLECULAR AND CELLULAR BIOLOGY, 34(14) 2732-2744, Jul, 2014 Peer-reviewed
p57 regulates T-cell development and prevents lymphomagenesis by balancing p53 activity and pre-TCR signaling

Akinobu Matsumoto, Shoichiro Takeishi, Keiichi I. Nakayama

BLOOD, 123(22) 3429-3439, May, 2014 Peer-reviewed
Zoledronic Acid Enhances Lipopolysaccharide-Stimulated Proinflammatory Reactions through Controlled Expression of SOCS1 in Macrophages

Daichi Muratsu, Daigo Yoshiga, Takaharu Taketomi, Tomohiro Onimura, Yoshihiro Seki, Akinobu Matsumoto, Seiji Nakamura

PLoS ONE, 8(7) e67906, Jul 9, 2013 Peer-reviewed
p57 controls adult neural stem cell quiescence and modulates the pace of lifelong neurogenesis

Shohei Furutachi, Akinobu Matsumoto, Keiichi I. Nakayama, Yukiko Gotoh

EMBO JOURNAL, 32(7) 970-981, Apr, 2013 Peer-reviewed

Misc.

Identification of unannotated ORFs and their physiological functions

市原知哉, 岩崎信太郎, 岩崎信太郎, 松本有樹修

実験医学, 40(12), 2022
eIF2D counteracts intrinsic ribosome destabilization (IRD) during translation elongation

市原知哉, 松本有樹修, 幡野敦, 松本雅記, 茶谷悠平, 田口英樹, 中山敬一

日本分子生物学会年会プログラム・要旨集(Web), 45th, 2022
Combinatorial analysis of translatome and proteome unveils the importance of hidden ORFs

松本有樹修, 市原知哉, 西田紘士, 今見考志, 石濱泰, 中山敬一

日本分子生物学会年会プログラム・要旨集(Web), 44th, 2021
Molecular mechanism and biological significance of non-AUG translation initiation revealed by precise identification of translation initiation sites

市原知哉, 松本有樹修, 西田紘士, 今見孝志, 石濱泰, 中山敬一

日本分子生物学会年会プログラム・要旨集(Web), 44th, 2021

Professional Memberships

THE MOLECULAR BIOLOGY SOCIETY OF JAPAN

Research Projects

ノンコーディングRNAから産生されるタンパク質の生理機能

科学研究費助成事業学術変革領域研究(A), 学術変革領域研究(A), 日本学術振興会, Nov, 2020 - Mar, 2025

松本有樹修
Non-AUG翻訳開始によるプロテオスタシス制御機構と疾患発症機構の解明

AMED-PRIME, 日本医療研究開発機構, Oct, 2021 - Mar, 2025

松本有樹修
横紋筋リボソームの破綻が引き起こす心機能不全の分子機構の解明

科学研究費助成事業挑戦的研究(萌芽), 挑戦的研究(萌芽), 日本学術振興会, Jun, 2022 - Mar, 2024

松本有樹修
Coding/Non-coding RNAの網羅的かつ精密な分類と性質の解析

科学研究費助成事業基盤研究(B), 基盤研究(B), 日本学術振興会, Apr, 2021 - Mar, 2024

松本有樹修
Mechanism of spermatogenesis by two novel polypeptides translated from the same locus

Grants-in-Aid for Scientific Research, Grant-in-Aid for Challenging Research (Exploratory), Japan Society for the Promotion of Science, Jul, 2020 - Mar, 2022

Matsumoto Akinobu
脳が進化により獲得した遺伝子による多様な個性形成メカニズムの解明

科学研究費助成事業新学術領域研究(研究領域提案型), 新学術領域研究(研究領域提案型), 日本学術振興会, Apr, 2019 - Mar, 2021

松本有樹修
Analysis of novel polypeptides involved in brain and neurological diseases

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, Apr, 2018 - Mar, 2021

Matsumoto Akinobu
Novel ubiquitin-like protein encoded by long non-coding RNAs

Grants-in-Aid for Scientific Research Grant-in-Aid for Challenging Research (Exploratory), Grant-in-Aid for Challenging Research (Exploratory), Japan Society for the Promotion of Science, Jun, 2018 - Mar, 2020

Akinobu Matsumoto
ノンコーディングRNAから翻訳される癌関連ポリペプチドの網羅的同定

科学研究費助成事業新学術領域研究(研究領域提案型), 新学術領域研究(研究領域提案型), 日本学術振興会, Apr, 2018 - Mar, 2020

松本有樹修
ユビキチンリガーゼFbxw7によるG0期維持機構と幹細胞制御に関する研究

科学研究費助成事業特別研究員奨励費, 特別研究員奨励費, 日本学術振興会, 2008 - 2010

松本有樹修

Profile Information

Research Interests

Research Areas

Research History

Papers

Misc.

Professional Memberships

Research Projects

Menu

Coauthors