Saving lives from maternal and neonatal complications has been a critical public health agenda in developing countries. Many developing countries, however, were unable to achieve their Millennium Development Goal targets for mortality reductions. While the coverage of individual services, such as antenatal care (ANC) and skilled delivery, has been improved, continuum of care (CoC) for women and their newborns has not been achieved.. This study aimed at evaluating the impact of the interventions that were intended to improve continuum of care among women and newborn in Ghana.