論文

査読有り
2020年9月

Prognostic factors and a new preliminary scoring system for remission of type 2 diabetes mellitus after laparoscopic sleeve gastrectomy.

Surgery today
  • Akira Umemura
  • ,
  • Akira Sasaki
  • ,
  • Hiroyuki Nitta
  • ,
  • Haruka Nikai
  • ,
  • Shigeaki Baba
  • ,
  • Takeshi Takahara
  • ,
  • Yasushi Hasegawa
  • ,
  • Hirokatsu Katagiri
  • ,
  • Shoji Kanno
  • ,
  • Yasushi Ishigaki

50
9
開始ページ
1056
終了ページ
1064
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1007/s00595-020-01990-z

PURPOSE: To evaluate the early remission rate of type 2 diabetes mellitus (T2DM) after laparoscopic sleeve gastrectomy (LSG) and establish a preliminary scoring system that predicts T2DM remission. METHODS: We assessed the outcomes of 49 morbidly obese patients with T2DM who underwent LSG between 2008 and 2018. The prognostic factors for T2DM remission 1 year post-LSG were identified and an original scoring system was established. We validated our scoring system by comparing it with the individualized metabolic surgery score and the ABCD score. RESULTS: The patients' mean body weight loss and percentage of excess weight loss were 34.4 kg and 59.4%, respectively, while the T2DM remission rate was 77.5%. The serum insulin level and the T2DM duration were independent predictive factors, the receiver-operating characteristic (ROC) curves for which revealed cutoff values of 12.7 ng/mL and 72 months, respectively. We set our system's score range at 0-2, whereby patients with higher scores have a good T2DM remission prognosis, as higher insulin levels, and/or shorter T2DM duration. Our scoring system had accuracy levels similar to those of the ABCD score with a simple stratification. CONCLUSION: Our preliminary scoring system attains a good level of accuracy for predicting T2DM remission.

リンク情報
DOI
https://doi.org/10.1007/s00595-020-01990-z
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/32170427

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