赤星軌征 (Noriyuki Akahoshi) - マイポータル

Preeclampsia-Like Features and Partial Lactation Failure in Mice Lacking Cystathionine γ-Lyase-An Animal Model of Cystathioninuria.

Akahoshi N, Handa H, Takemoto R, Kamata S, Yoshida M, Onaka T, Ishii I

International journal of molecular sciences 20(14) 2019年7月17日査読有り

Dietary selenium deficiency or selenomethionine excess drastically alters organ selenium contents without altering the expression of most selenoproteins in mice.

Akahoshi N, Anan Y, Hashimoto Y, Tokoro N, Mizuno R, Hayashi S, Yamamoto S, Shimada KI, Kamata S, Ishii I

The Journal of nutritional biochemistry 69 120-129 2019年7月査読有り

Lysophosphatidic acid-induced YAP/TAZ activation promotes developmental angiogenesis by repressing Notch ligand Dll4.

Yasuda D, Kobayashi D, Akahoshi N, Ohto-Nakanishi T, Yoshioka K, Takuwa Y, Mizuno S, Takahashi S, Ishii S

The Journal of clinical investigation 130(10) 4332-4349 2019年7月査読有り

Abnormal Amino Acid Profiles of Blood and Cerebrospinal Fluid from Cystathionine β-Synthase-Deficient Mice, an Animal Model of Homocystinuria.

Akahoshi N, Yokoyama A, Nagata T, Miura A, Kamata S, Ishii I

Biological & pharmaceutical bulletin 42(6) 1054-1057 2019年査読有り

The Gα12/13-coupled receptor LPA4 limits proper adipose tissue expansion and remodeling in diet-induced obesity.

Yanagida K, Igarashi H, Yasuda D, Kobayashi D, Ohto-Nakanishi T, Akahoshi N, Sekiba A, Toyoda T, Ishijima T, Nakai Y …

JCI insight 3(24) 2018年12月査読有り

2D DIGE proteomic analysis reveals fasting-induced protein remodeling through organ-specific transcription factor(s) in mice.

Kamata S, Yamamoto J, Ohtani H, Tosaka Y, Yoshikawa S, Akahoshi N, Ishii I

FEBS open bio 8(9) 1524-1543 2018年9月査読有り

Cystathionine γ-Lyase-Produced Hydrogen Sulfide Controls Endothelial NO Bioavailability and Blood Pressure.

Szijártó IA, Markó L, Filipovic MR, Miljkovic JL, Tabeling C, Tsvetkov D, Wang N, Rabelo LA, Witzenrath M, Diedrich A …

Hypertension (Dallas, Tex. : 1979) 71(6) 1210-1217 2018年6月査読有り

LPA5 signaling is involved in multiple sclerosis-mediated neuropathic pain in the cuprizone mouse model.

Ryoko Tsukahara, Shinji Yamamoto, Keisuke Yoshikawa, Mari Gotoh, Tamotsu Tsukahara, Hiroyuki Neyama, Satoshi Ishii, Noriyuki Akahoshi, Keisuke Yanagida, Hayakazu Sumida …

Journal of pharmacological sciences 136(2) 93-96 2018年2月査読有り

Mutations in Homocysteine Metabolism Genes Increase Keratin N-Homocysteinylation and Damage in Mice.

Borowczyk K, Wróblewski J, Suliburska J, Akahoshi N, Ishii I, Jakubowski H

International journal of genomics 2018 7570850 2018年査読有り

Lysophosphatidic acid receptors LPA(4) and LPA(6) differentially promote lymphocyte transmigration across high endothelial venules in lymph nodes

Erina Hata, Naoko Sasaki, Akira Takeda, Kazuo Tohya, Eiji Umemoto, Noriyuki Akahoshi, Satoshi Ishii, Kana Bando, Takaya Abe, Kuniyuki Kano …

INTERNATIONAL IMMUNOLOGY 28(6) 283-292 2016年6月査読有り

Fibroblastic reticular cell-derived lysophosphatidic acid regulates confined intranodal T-cell motility

Akira Takeda, Daichi Kobayashi, Keita Aoi, Naoko Sasaki, Yuki Sigiura, Hidemitsu Igarashi, Kazuo Tohya, Asuka Inoue, Erina Hata, Noriyuki Akahoshi …

ELIFE 5 e10561 2016年2月査読有り

Hyperhomocysteinemia abrogates fasting-induced cardioprotection against ischemia/reperfusion by limiting bioavailability of hydrogen sulfide anions

Shintaro Nakano, Isao Ishii, Ken Shinmura, Kayoko Tamaki, Takako Hishiki, Noriyuki Akahoshi, Tomoaki Ida, Tsuyoshi Nakanishi, Shotaro Kamata, Yoshito Kumagai …

JOURNAL OF MOLECULAR MEDICINE-JMM 93(8) 879-889 2015年8月査読有り

The lysophosphatidic acid receptor LPA(4) regulates hematopoiesis-supporting activity of bone marrow stromal cells

Hidemitsu Igarashi, Noriyuki Akahoshi, Takayo Ohto-Nakanishi, Daisuke Yasuda, Satoshi Ishii

SCIENTIFIC REPORTS 5 11410 2015年6月査読有り

Hemizygosity of transsulfuration genes confers increased vulnerability against acetaminophen-induced hepatotoxicity in mice

Yoshifumi Hagiya, Shotaro Kamata, Saya Mitsuoka, Norihiko Okada, Saori Yoshida, Junya Yamamoto, Rika Ohkubo, Yumi Abiko, Hidenori Yamada, Noriyuki Akahoshi …

TOXICOLOGY AND APPLIED PHARMACOLOGY 282(2) 195-206 2015年1月査読有り

2D DIGE proteomic analysis highlights delayed postnatal repression of α-fetoprotein expression in homocystinuria model mice.

Kamata S, Akahoshi N, Ishii I

FEBS open bio 5 535-541 2015年査読有り

Neutral aminoaciduria in cystathionine β-synthase-deficient mice; an animal model of homocystinuria.

Akahoshi N, Kamata S, Kubota M, Hishiki T, Nagahata Y, Matsuura T, Yamazaki C, Yoshida Y, Yamada H, Ishizaki Y …

American journal of physiology. Renal physiology 306(12) F1462-F1476 2014年6月査読有り

TDAG8 activation inhibits osteoclastic bone resorption

Hisako Hikiji, Daisuke Endo, Kyoji Horie, Takeshi Harayama, Noriyuki Akahoshi, Hidemitsu Igarashi, Yasuyuki Kihara, Keisuke Yanagida, Junji Takeda, Takehiko Koji …

FASEB JOURNAL 28(2) 871-879 2014年2月査読有り

Methionine excess in diet induces acute lethal hepatitis in mice lacking cystathionine γ-lyase, an animal model of cystathioninuria.

Yamada H, Akahoshi N, Kamata S, Hagiya Y, Hishiki T, Nagahata Y, Matsuura T, Takano N, Mori M, Ishizaki Y …

Free radical biology & medicine 52(9) 1716-1726 2012年5月査読有り

TOF-SIMS imaging of halide/thiocyanate anions and hydrogen sulfide in mouse kidney sections using silver-deposited plates

Noriyuki Akahoshi, Itsuko Ishizaki, Masayuki Naya, Toshihiko Maekawa, Shougo Yamazoe, Tadashi Horiuchi, Mayumi Kajimura, Yoshiharu Ohashi, Makoto Suematsu, Isao Ishii

ANALYTICAL AND BIOANALYTICAL CHEMISTRY 402(5) 1859-1864 2012年2月査読有り

Frequent spontaneous seizures followed by spatial working memory/anxiety deficits in mice lacking sphingosine 1-phosphate receptor 2

Noriyuki Akahoshi, Yasuki Ishizaki, Hiroki Yasuda, Yoshiya L. Murashima, Toshikazu Shinba, Kaoru Goto, Toshiyuki Himi, Jerold Chun, Isao Ishii

EPILEPSY & BEHAVIOR 22(4) 659-665 2011年12月査読有り

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