Eijiro Sakamoto

Profile Information

Affiliation: Senior Assistant Professor, Periodontology and Endodontology, Nagasaki University

J-GLOBAL ID: 201801012652482356
researchmap Member ID: B000343297

Research Interests

Research Areas

Awards

Feb, 2020

日本歯科保存学会奨励賞, 終末糖化産物と LPS は骨細胞由来スクレロスチンを介し骨芽細胞分化を抑制する, 日本歯科保存学会

坂本英次郎
Sep, 2016

第21回日本糖尿病教育・看護学会学術集会 JADEN21 AWARD, JADEN 21st AWARD, Japan Academy of Diabetes Education and Nursing

Yumi Kuwamura, 澄川真珠子, 瀧川稲子, 大和光, Eijiro Sakamoto, Toshihiko Nagata

Papers

Diagnosis of inflammatory peri-implant diseases using an immunochromatographic assay for calprotectin in peri-implant crevicular fluid.

Rie Kido, Jun-Ichi Kido, Yasufumi Nishikawa, Eijiro Sakamoto, Yoritoki Tomotake, Hiromichi Yumoto

International journal of implant dentistry, 7(1) 106-106, Oct 8, 2021
Gan-Lu-Yin (Kanroin), Traditional Chinese Herbal Extracts, Reduces Osteoclast Differentiation In Vitro and Prevents Alveolar Bone Resorption in Rat Experimental Periodontitis

Yuji Inagaki, Jun-Ichi Kido, Yasufumi Nishikawa, Rie Kido, Eijiro Sakamoto, Mika Bando, Koji Naruishi, Toshihiko Nagata, Hiromichi Yumoto

Journal of clinical medicine, 10(3), Jan 20, 2021
Various roles of calprotectin in periodontal disease and its possibility as a diagnostic marker for periodontal disease

Eijiro Sakamoto, Yuka Hiroshima, Jun-ichi Kido, Yasufumi Nishikawa, Koji Naruishi, Rie Kido, Hiromichi Yumoto

Nihon Shishubyo Gakkai Kaishi (Journal of the Japanese Society of Periodontology), 62(4) 193-199, Dec 28, 2020
カルプロテクチンの歯周病病態における多様な役割と歯周病診断マーカーとしての可能性

坂本英次郎, 廣島佑香, 木戸淳一, 西川泰史, 成石浩司, 木戸理恵, 湯本浩通

日本歯周病学会会誌, 62(4) 193-199, Dec, 2020
Advanced glycation end‐products increase lipocalin 2 expression in human oral epithelial cells

Rie Kido, Yuka Hiroshima, Jun‐ichi Kido, Takahisa Ikuta, Eijiro Sakamoto, Yuji Inagaki, Koji Naruishi, Hiromichi Yumoto

Journal of Periodontal Research, 55(4) 539-550, Aug, 2020
講義および実習試験の評価による歯周病学教育のあり方の考察

成石浩司, 坂本英次郎, 生田貴久, 木戸理恵, 木戸淳一, 湯本浩通

日本歯科保存学雑誌, 63(1) 22-29, Feb, 2020
S100A9 Increases IL-6 and RANKL Expressions through MAPKs and STAT3 Signaling Pathways in Osteocyte-Like Cells.

Ryosuke Takagi, Eijiro Sakamoto, Jun-Ichi Kido, Yuji Inagaki, Yuka Hiroshima, Koji Naruishi, Hiromichi Yumoto

BioMed research international, 2020 7149408-7149408, 2020 Peer-reviewed
Modified diabetes oral health assessment tool (M-DiOHAT©) for nurses and their association with efficacy beliefs and outcome expectancies in patients with diabetes

Yumi Kuwamura, Sumiko Yoshida, Kiyoe Kurahashi, Masuko Sumikawa, Eijiro Sakamoto, Ken-ichi Aihara, Hiromichi Yumoto, Akio Kuroda, Itsuro Endo, Toshiyuki Yasui …

JNI : The Journal of Nursing Investigation, Vol.17(No.2) (in press)-(inpress), Jan, 2020 Peer-reviewed
6-Shogaol Inhibits Advanced Glycation End-Products-Induced IL-6 and ICAM-1 Expression by Regulating Oxidative Responses in Human Gingival Fibroblasts.

Kohei Nonaka, Mika Bando, Eijiro Sakamoto, Yuji Inagaki, Koji Naruishi, Hiromichi Yumoto, Jun-Ichi Kido

Molecules (Basel, Switzerland), 24(20), Oct 15, 2019 Peer-reviewed
Assessing the oral health of in-patients with diabetes using a clinical version of the diabetes oral health assessment tool? and its association with dental examinations

Yumi Kuwamura, Eijiro Sakamoto, Masuko Sumikawa, Munehide Matsuhisa, Daisuke Hinode, Hirokazu Uemura, Sachi Kishida

The Journal of Medical Investigation : JMI, Vol.66(No.3,4) 328-336, Aug 2, 2019 Peer-reviewed
全顎的歯周治療に伴って関節リウマチの状態が改善した一症例

稲垣裕司, 生田貴久, 坂本英次郎, 木戸淳一, 湯本浩通

特定非営利活動法人日本歯科保存学会学術大会プログラムおよび講演抄録集, 150回 60-60, May, 2019
周期性好中球減少症を有する母娘に認められた重度歯周炎の症例

二宮雅美, 坂本英次郎, 成石浩司, 生田貴久, 高木亮輔, 畑中加珠, 岡本憲太郎, 小野晋太郎, 高柴正悟, 湯本浩通

日本歯周病学会会誌, 61(春季特別) 164-164, May, 2019
Advanced glycation end-product 2 and Porphyromonas gingivalis lipopolysaccharide increase sclerostin expression in mouse osteocyte-like cells.

Sakamoto E, Kido JI, Takagi R, Inagaki Y, Naruishi K, Nagata T, Yumoto H

Bone, 122 22-30, May, 2019 Peer-reviewed
Calprotectin and cross-linked N-telopeptides of type I collagen levels in crevicular fluid from implant sites with peri-implant diseases: a pilot study.

Sakamoto E, Kido R, Tomotake Y, Naitou Y, Ishida Y, Kido JI

International journal of implant dentistry, 4(1) 26, Sep, 2018 Peer-reviewed
Advanced glycation end-products increase IL-6 and ICAM-1 expression via RAGE, MAPK and NF-kB pathways in human gingival fibroblasts

Kohei Nonaka, Yukari Kajiura, Mika Bandou, Eijiro Sakamoto, Yuji Inagaki, JH Lew, Koji Naruishi, Takahisa Ikuta, Kaya Yoshida, Tesuo Kobayashi …

Journal of Periodontal Research, Vol.53(No.3) 334-344, Jun, 2018 Peer-reviewed
Advanced glycation end-products increase IL-6 and ICAM-1 expression via RAGE, MAPK and NF-κB pathways in human gingival fibroblasts

K. Nonaka, Y. Kajiura, M. Bando, E. Sakamoto, Y. Inagaki, J. H. Lew, K. Naruishi, T. Ikuta, K. Yoshida, T. Kobayashi …

Journal of Periodontal Research, 53(3) 334-344, Jun, 2018 Peer-reviewed
インプラント周囲溝滲出液中のカルプロテクチンとNTxを用いたインプラント疾患の診断

木戸理恵, 坂本英次郎, 板東美香, 稲垣裕司, 二宮雅美, 美原智恵, 生田貴久, 成石浩司, 永田俊彦, 木戸淳一 …

日本歯周病学会会誌, 60(春季特別) 132-132, May, 2018
The utilization of the Diabetes Oral Health Assessment Tool? for Nurses by Diabetes Nurse Specialists

Yumi Kuwamura, Masuko Sumikawa, Eijiro Sakamoto, Sachi Kishida

JNI : The Journal of Nursing Investigation, Vol.15(No.1,2) 1-10, Mar 31, 2018 Peer-reviewed
Advanced glycation end-products and Porphyromonas gingivalis lipopolysaccharide increase calprotectin expression in human gingival epithelial cells

Yuka Hiroshima, Eijiro Sakamoto, Kaya Yoshida, Kaori Abe, Koji Naruishi, Takenori Yamamoto, Yasuo Shinohara, Jun Ichi Kido, Carolyn L. Geczy

Journal of Cellular Biochemistry, 119(2) 1591-1603, Feb, 2018 Peer-reviewed
Advanced glycation end-products and Porphyromonas gingivalis lipopolysaccharide increase calprotectin expression in human gingival epithelial cells.

Yuka Hiroshima, Eijiro Sakamoto, Kaya Yoshida, Kaori Abe, Koji Naruishi, Takenori Yamamoto, Yasuo Shinohara, Jun-ichi Kido, Carolyn L Geczy

Journal of Cellular Biochemistry, Vol.119(No.2) 1591-1603, 2018 Peer-reviewed

Misc.

イムノクロマト法を用いたカルプロテクチンの測定によるインプラント疾患の診断

木戸理恵, 木戸淳一, 坂本英次郎, 西川泰史, 廣島佑香, 湯本浩通

日本歯周病学会会誌(Web), 62, 2020
Various roles of calprotectin in periodontal disease and its possibility as a diagnostic marker for periodontal disease

坂本英次郎, 廣島佑香, 木戸淳一, 西川泰史, 成石浩司, 木戸理恵, 湯本浩通

日本歯周病学会会誌(Web), 62(4), 2020
甘露飲エキス配合製剤はラット実験的歯周炎において歯槽骨吸収を抑制する

稲垣裕司, 野中康平, 高木亮輔, 西川泰史, 木戸理恵, 坂本英次郎, 成石浩司, 木戸淳一, 湯本浩通

日本歯周病学会会誌(Web), 60, 2018
甘露飲エキスは破骨細胞と骨芽細胞の分化制御を介してラット実験的歯周炎の歯槽骨吸収を抑制する

稲垣裕司, 高木亮輔, 西川泰史, 木戸理恵, 坂本英次郎, 成石浩司, 木戸淳一, 湯本浩通

日本歯科保存学会学術大会プログラムおよび講演抄録集(Web), 149th, 2018
DiOHAT(Diabetes Oral Health Assessment Tool for Nurses)臨床版を用いた看護アセスメント結果の実態

桑村由美, 坂本英次郎, 澄川真珠子, 大和光, 瀧川稲子, 村田裕美, 永田俊彦

日本糖尿病教育・看護学会誌, 21(特別号) 119-119, Aug, 2017
アドバンスドOSCEを見据えた当科の模擬OSCEの概要

美原智恵, 成石浩司, 板東美香, 西川泰史, LEW Jung Hwan, 坂本英次郎, 生田貴久, 河野薫, 梶浦由加里, 橋本万里 …

Journal of Oral Health and Biosciences, 29(2), 2017
Effects of advanced glycation end-products on pathogenesis of diabetes-associated periodontitis

Jun-ichi Kido, Mika Bandou, E Sakamoto, Yukari Kajiura, Toshihiko Nagata

Journal of the Japanese Association of Periodontology, Vol.56(No.1) 17-24, 2014

Presentations

S100A9 は MAPK および STAT3 経路を介して骨細胞における IL-6 と RANKL の発現を調節する

高木亮輔, 坂本英次郎, 稲垣裕司, 成石浩司, 木戸淳一, 湯本浩通

第150回春季日本歯科保存学会学術大会, Jun 27, 2019
The Relationship Between the Modified Diabetes Oral Health Assessment Tool? for Nurses, Self-Efficacy Scale, and Outcome Expectancy Scale for Self-Care of Patients with Periodontal Disease

Yumi Kuwamura, Sumiko Yoshida, Kiyoe Kurahashi, Masuko Sumikawa, Eijiro Sakamoto, Ken-ichi Aihara, Hiromichi Yumoto, Munehide Matsuhisa, Itsuro Endo, Toshiyuki Yasui, Sachi Kishida

2nd Technological Competency as Caring in the Health Sciences 2018, Aug 18, 2018
AGEs and LPS inhibit osteoblastic differentiation via sclerostin in osteocytes

Eijiro Sakamoto, Yuji Inagaki, Ryosuke Takagi, Jun-ichi Kido, Hiromichi Yumoto

Jul 26, 2018
終末糖化産物と LPS は骨細胞由来スクレロスチンを介し骨芽細胞分化を抑制する

坂本英次郎, 高木亮輔, 稲垣裕司, 木戸淳一, 湯本浩通

第148回春季日本歯科保存学会学術大会, Jun 15, 2018
カルプロテクチンはマウス骨細胞の炎症および骨代謝関連因子の発現を制御する

Ryosuke Takagi, Eijiro Sakamoto, Yuji Inagaki, Yuka Hiroshima, Koji Naruishi, Jun-ichi Kido, Hiromichi Yumoto

第61回春季日本歯周病学会学術大会, Jun 1, 2018
DiOHAT(Diabetes Oral Health Assessment Tool for Nurses)臨床版を用いた看護アセスメント結果の実態

Yumi Kuwamura, Eijiro Sakamoto, 澄川真珠子, 大和光, 瀧川稲子, Hiromi Murata, Toshihiko Nagata

The Journal of Japan Academy of Diabetes Education and Nursing, Sep 16, 2017, Japan Academy of Diabetes Education and Nursing
新規歯周組織再生剤「リグロス歯科用液キット」の有効性

Masami Ninomiya, Yuji Inagaki, Chie Mihara-Wada, Mika Bandou, Yukiko Nakajima, Eijiro Sakamoto, Ikuta Takahisa, Nishikawa Yasufumi, Jung-Hwan Lew, Kido Rie, Takagi Ryousuke, Nonaka Kouhei, Koji Naruishi, Jun-ichi Kido, Toshihiko Nagata

四国歯学会第51回例会, Jun 29, 2017
アドバンスドOSCEを見据えた当科の模擬OSCEの概要

Chie Mihara-Wada, Koji Naruishi, Mika Bandou, 西川泰史, Hwan Jung Lew, Eijiro Sakamoto, 生田貴久, 河野薫, Yukari Kajiura, 橋本万里, Yukiko Nakajima, Yuji Inagaki, Masami Ninomiya, Jun-ichi Kido, Toshihiko Nagata

Shikoku Dental Research, Jun 23, 2017
Nurses' Implementation and Opinion of Assessment of Oral Health Behavior in Patients with Diabetes

Yumi Kuwamura, Sumikawa Masuko, Eijiro Sakamoto, Takikawa Ineko, Yamako Hikari, Hirokazu Uemura, Sachi Kishida, Toshihiko Nagata, Munehide Matsuhisa

Journal of Diabetes Investigation, May 20, 2017, Asian Association for the Stady of Diabetes
最終糖化産物とLPSはMAPKおよびNF-kBを介してマウス骨細胞のスクレロスチンの発現を調節する

Eijiro Sakamoto, Yuji Inagaki, Jun-ichi Kido, Takagi Ryosuke, Koji Naruishi, Toshihiko Nagata

第60回春季日本歯周病学会学術大会, May, 2017
Advanced Glycation End-Products Increase Calprotectin in Human Gingival Epithelial Cells

Yuka Hiroshima, Eijiro Sakamoto, Kaori Abe, Kaya Yoshida, Koji Naruishi, Toshihiko Nagata, Yasuo Shinohara, Geczy Carolyn, Jun-ichi Kido

The 95th General Session & Exhibition of the International Association for Dental Research (IADR), Mar 23, 2017, International Association for Dental Research
AGE and Porphyromonas gingival is-LPS Increase Sclerostin Expression in Osteocytes

Eijiro Sakamoto, Yuji Inagaki, Jun-ichi Kido, Takagi Ryosuke, Koji Naruishi, Toshihiko Nagata

International Association for Dental Research, Mar 21, 2017
マウス骨細胞株MLO-Y4-A2のスクレロスチン発現における最終糖化産物およびLPSの影響

Eijiro Sakamoto, Yuji Inagaki, Jun-ichi Kido, 高木亮輔, 生田貴久, Koji Naruishi, Toshihiko Nagata

第145回日本歯科保存学会秋季学術大会, Oct 28, 2016
最終糖化産物はヒト歯肉上皮細胞におけるS100A8およびS100A9発現を上昇する

Yuka Hiroshima, Jun-ichi Kido, Eijiro Sakamoto, 阿部佳織, Kaya Yoshida, Toshihiko Nagata, Yasuo Shinohara

第59回秋季日本歯周病学会学術大会, Oct 7, 2016
最終糖化産物はヒト歯肉線維芽細胞におけるIL-6およびICAM-1の発現を増加する

Mika Bandou, Yukari Kajiura, 野中康平, Eijiro Sakamoto, Koji Naruishi, Jun-ichi Kido, Toshihiko Nagata

第59回秋季日本歯周病学会学術大会, Oct 7, 2016
糖尿病口腔保健行動アセスメントシートDiOHAT実用版の臨床使用の試みと実用化に向けた課題

Yumi Kuwamura, 澄川真珠子, 瀧川稲子, 大和光, Eijiro Sakamoto, Toshihiko Nagata

The Journal of Japan Academy of Diabetes Education and Nursing, Sep 19, 2016
アドバンスOSCEを見据えた当科の模擬OSCEの概要

美原智恵, Koji Naruishi, Mika Bandou, 西川泰史, Jung-Hwan Lew, Eijiro Sakamoto, 生田貴久, 河野薫, Yukari Kajiura, 橋本万里, Yukiko Nakajima, Yuji Inagaki, Masami Ninomiya, Jun-ichi Kido, Toshihiko Nagata

第49回四国歯学会例会, Jun 23, 2016
骨細胞培養系におけるAGEとLPS刺激によるスクレロスチンの発現上昇

Yuji Inagaki, Eijiro Sakamoto, Jun-ichi Kido, Yukari Kajiura, Toshihiko Nagata

第59回春季日本歯周病学会学術大会, May 20, 2016
糖尿病関連歯周炎の歯槽骨破壊におけるスクレロスチンの役割

Eijiro Sakamoto, Yuji Inagaki, Jun-ichi Kido, Yukari Kajiura, Jung-Hwan Lew, Toshihiko Nagata

第59回日本糖尿病学会年次学術集会, May 19, 2016
ヒト口腔上皮細胞と歯肉線維芽細胞において低酸素環境が誘導する遺伝子発現の比較

Jun-ichi Kido, Mika Bandou, Yukiko Nakajima, Yukari Kajiura, Yuji Inagaki, 生田貴久, Eijiro Sakamoto, Koji Naruishi, Toshihiko Nagata

第143回日本歯科保存学会秋季学術大会, Nov 12, 2015

Professional Memberships

Jun, 2010 - Present

Japanese Society of Conservative Dentistry
May, 2009 - Present

Japanese Society of Periodontology

Research Projects

糖尿病患者の口腔保健行動アセスメントシートを用いた看護支援プログラムの開発

Grants-in-Aid for Scientific Research, Apr, 2017 - Mar, 2020

桑村由美
糖尿病関連歯周炎における骨細胞ギャップ結合を介した細胞間情報伝達機構の解明

科学研究費助成事業若手研究, 若手研究, 日本学術振興会, Apr, 2019 - Mar, 2020

坂本英次郎
最終糖化産物とリポ多糖による骨細胞スクレロスチンの発現調節と骨代謝への影響

Grants-in-Aid for Scientific Research, Apr, 2016 - Mar, 2019

坂本英次郎
Development of the diabetes oral health assessment tool for nurses to help the patients with diabetes with their oral health behaviors simply

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2014 - Mar, 2017

KUWAMURA Yumi

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