朝日通雄 (Michio Asahi) - 論文

Rivaroxaban Attenuates Right Ventricular Remodeling in Rats with Pulmonary Arterial Hypertension.

Hideki Imano, Ryuji Kato, Atsuo Nomura, Maki Tamura, Yudai Yamaguchi, Yoshio Ijiri, Hong Wu, Takashi Nakano, Yoshikatsu Okada, Takehiro Yamaguchi, Yasukatsu Izumi, Minoru Yoshiyama, Michio Asahi, Tetsuya Hayashi

Biological & pharmaceutical bulletin 44(5) 669-677 2021年5月1日

Iron derived from autophagy-mediated ferritin degradation induces cardiomyocyte death and heart failure in mice

Jumpei Ito, Shigemiki Omiya, Mara-Camelia Rusu, Hiromichi Ueda, Tomokazu Murakawa, Yohei Tanada, Hajime Abe, Kazuki Nakahara, Michio Asahi, Manabu Taneike, Kazuhiko Nishida, Ajay M Shah, Kinya Otsu

eLife 10 2021年2月2日

消化管におけるtranslational research O-GlcNAc修飾はFOXM1を安定化することで癌の進展に働く

上田康裕, 森脇一将, 小嶋融一, 竹内利寿, 朝日通雄, 樋口和秀

日本消化管学会雑誌 5(Suppl.) 169-169 2021年1月

Fluctuation in O-GlcNAcylation inactivates STIM1 to reduce store-operated calcium ion entry via downregulation of Ser621 phosphorylation

Atsuo Nomura, Shunichi Yokoe, Kiichiro Tomoda, Takatoshi Nakagawa, Francisco Javier Martin-Romero, Michio Asahi

Journal of Biological Chemistry jbc.RA120.014271-jbc.RA120.014271 2020年10月6日

Enhancement of O‑linked N‑acetylglucosamine modification promotes metastasis in patients with colorectal cancer and concurrent type 2 diabetes mellitus

Yutaka Naka, Toshihiko Okada, Takatoshi Nakagawa, Eiko Kobayashi, Yuka Kawasaki, Yasuyoshi Tanaka, Hideki Tawa, Yuki Hirata, Ken Kawakami, Kazuki Kakimoto, Takuya Inoue, Toshihisa Takeuchi, Shinya Fukunishi, Yoshinobu Hirose, Kazuhisa Uchiyama, Michio Asahi, Kazuhide Higuchi

Oncology Letters 20(2) 1171-1178 2020年5月22日査読有り

Exacerbation of autoimmune myocarditis by an immune checkpoint inhibitor is dependent on its time of administration in mice.

Kenjiro Tsuruoka, Shigeo Wakabayashi, Hirofumi Morihara, Ninso Matsunaga, Yasuhito Fujisaka, Isao Goto, Akihisa Imagawa, Michio Asahi

International journal of cardiology 313 67-75 2020年4月13日査読有り

O-GlcNAcylation-mediated degradation of FBXL2 stabilizes FOXM1 to induce cancer progression.

Yasuhiro Ueda, Kazumasa Moriwaki, Toshihisa Takeuchi, Kazuhide Higuchi, Michio Asahi

Biochemical and biophysical research communications 521(3) 632-638 2020年1月15日査読有り

Intravenously Injected Pluripotent Stem Cell–derived Cells Form Fetomaternal Vasculature and Prevent Miscarriage in Mouse

Atsushi Daimon, Hirofumi Morihara, Kiichiro Tomoda, Natsuko Morita, Yoshinori Koishi, Kazuyoshi Kanki, Masahide Ohmichi, Michio Asahi

Cell Transplantation 29 096368972097045-096368972097045 2020年1月1日

Overexpression of Na+/H+ exchanger 1 specifically induces cell death in human iPS cells via sustained activation of the Rho kinase ROCK.

Shigeo Wakabayashi, Hirofumi Morihara, Shunichi Yokoe, Takatoshi Nakagawa, Kazumasa Moriwaki, Kiichiro Tomoda, Michio Asahi

The Journal of biological chemistry 294(51) 19577-19588 2019年12月20日査読有り

Augmented O-GlcNAcylation attenuates intermittent hypoxia-induced cardiac remodeling through the suppression of NFAT and NF-κB activities in mice.

Nakagawa T, Furukawa Y, Hayashi T, Nomura A, Yokoe S, Moriwaki K, Kato R, Ijiri Y, Yamaguchi T, Izumi Y, Yoshiyama M, Asahi M

Hypertension research : official journal of the Japanese Society of Hypertension 42(12) 1858-1871 2019年12月査読有り

ヒトiPS細胞を用いたゲフィチニブ起因性肝障害のin vitroモデルの樹立とメカニズム解析

朝日通雄, 友田紀一郎, 渡辺満里奈, 藤阪保仁

臨床薬理 50(Suppl.) S264-S264 2019年11月査読有り

Cardiac Regeneration by Statin-Polymer Nanoparticle-Loaded Adipose-Derived Stem Cell Therapy in Myocardial Infarction.

Ryo Yokoyama, Masaaki Ii, Misaki Masuda, Yasuhiko Tabata, Masaaki Hoshiga, Nobukazu Ishizaka, Michio Asahi

Stem cells translational medicine 8(10) 1055-1067 2019年10月査読有り

O -GlcNAc修飾上昇はFBXL2によるFOXM1のポリユビキチン化を抑制してFOXM1を増加させる(Elevated O-GlcNAcylation increases FOXM1 via suppression of FBXL2-mediated its poly-ubiquitination)

森脇一将, 上田康裕, 樋口和秀, 朝日通雄

日本癌学会総会記事 78回 E-1026 2019年9月

Induced 2C Expression and Implantation-Competent Blastocyst-like Cysts from Primed Pluripotent Stem Cells

Cody Kime, Hiroshi Kiyonari, Satoshi Ohtsuka, Eiko Kohbayashi, Michio Asahi, Shinya Yamanaka, Masayo Takahashi, Kiichiro Tomoda

Stem Cell Reports 13(3) 485-498 2019年9月査読有り

ELEVATED O-GLCNACYLATION INCREASES FOXM1 PROTEIN VIA SUPPRESSION OF ITS POLY-UBIQUITINATION AND SUBSEQUENT PROTEASOMAL DEGRADATION

Ueda Yasuhiro, Moriwaki Kazumasa, Sugawara Noriaki, Fukumoto Masanobu, Harada Satoshi, Ota Kazuhiro, Kojima Yuichi, Takeuchi Toshihisa, Higuchi Kazuhide, Asahi Michio

GASTROENTEROLOGY 156(6) S1091 2019年5月査読有り

Autophagy deficiency exacerbates colitis through excessive oxidative stress and MAPK signaling pathway activation.

Minori Kubota, Kazuki Kakimoto, Takatoshi Nakagawa, Eiko Koubayashi, Kei Nakazawa, Hideki Tawa, Yuki Hirata, Toshihiko Okada, Ken Kawakami, Akira Asai, Shuhei Hosomi, Toshihisa Takeuchi, Shinya Fukunishi, Takuya Inoue, Michio Asahi, Kazuhide Higuchi

PloS one 14(11) e0225066 2019年査読有り

Establishment of a novel mouse xenograft model of human uterine leiomyoma

Yusuke Suzuki, Masaaki Ii, Takashi Saito, Yoshito Terai, Yasuhiko Tabata, Masahide Ohmichi, Michio Asahi

Scientific Reports 8(1) 8872 2018年12月1日査読有り

O-GlcNAc修飾の上昇はFOXM1タンパクのプロテアソームでの分解を抑制してその発現を安定化している(Elevated O-GlcNAcylation stabilizes FOXM1 protein via suppression of its proteasomal degradation)

森脇一将, 上田康裕, 樋口和秀, 朝日通雄

日本癌学会総会記事 77回 2124-2124 2018年9月

Interleukin-18 in cardiomyocyte: A novel therapeutic target for attenuating cardiac remodeling. Response

Yoshitaka Okuhara, Shunichi Yokoe, Michio Asahi, Haruki Okamura, Tohru Masuyama, Shinichi Hirotani

International Journal of Cardiology 266 221 2018年9月1日査読有り

TRKB tyrosine kinase receptor is a potential therapeutic target for poorly differentiated oral squamous cell carcinoma

Kazumasa Moriwaki, Yusuke Ayani, Hiroko Kuwabara, Tetsuya Terada, Ryo Kawata, Michio Asahi