川口敦史 (Kawaguchi Atsushi) - 論文

Macrocyclic Azapeptide Nitriles: Structure-Based Discovery of Potent SARS-CoV-2 Main Protease Inhibitors as Antiviral Drugs.

Julian Breidenbach, Rabea Voget, Yaoyao Si, Alexandra Hingst, Tobias Claff, Katharina Sylvester, Valentina Wolf, Vesa Krasniqi, Abibe Useini, Norbert Sträter …

Journal of medicinal chemistry 67(11) 8757-8790 2024年6月13日

Detection of Active SARS-CoV-2 3CL Protease in Infected Cells Using Activity-Based Probes with a 2,6-Dichlorobenzoyloxymethyl Ketone Reactive Warhead.

Yuki Yamauchi, Sho Konno, Noriko Omura, Narumi Yoshioka, Alexandra Hingst, Michael Gütschow, Christa E Müller, Akihiro Taguchi, Atsuhiko Taniguchi, Atsushi Kawaguchi …

ACS chemical biology 19(5) 1028-1034 2024年5月17日

Di-n-butyl phthalate promotes the neural differentiation of mouse embryonic stem cells through neurogenic differentiation 1.

Ying-Chu Lin, Kenly Wuputra, Kohsuke Kato, Chia-Chen Ku, Shigeo Saito, Michiya Noguchi, Yukio Nakamura, Michael Hsiao, Chang-Shen Lin, Deng-Chyang Wu …

Environmental pollution (Barking, Essex : 1987) 347 123722-123722 2024年4月15日

Intramolecular interaction of NEP regulated by CRM1 ensures the unidirectional transport of M1 for the nuclear export of influenza viral ribonucleoprotein

Mikako Hirohama, Shun Yamashita, Masamitsu N. Asaka, Takahiro Kuroki, Atsushi Kawaguchi

Frontiers in Virology 3 2023年8月17日

Systematic Surveillance of an Emerging Picornavirus among Cattle and Sheep in China.

Chengyuan Ji, Yao Zhang, Yiqiu Feng, Xinqin Zhang, Jiale Ma, Zihao Pan, Atsushi Kawaguchi, Huochun Yao

Microbiology spectrum 11(3) e0504022 2023年6月15日

Zinc binding of a Cys2His2-type zinc finger protein is enhanced by the interaction with DNA.

Bálint Hajdu, Éva Hunyadi-Gulyás, Kohsuke Kato, Atsushi Kawaguchi, Kyosuke Nagata, Béla Gyurcsik

Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 2023年2月23日

Nano-visualization of the in vitro antiviral activity of black tea based on production area using a liposome-based virus membrane model.

Masumi Iijima, Atsushi Kawaguchi, Yukino Ogura, Ryotaro Yoshimoto, Moemi Kaneda, Kota Kera, Shun'ichi Kuroda, Tsutomu Nakayama

Bioscience, biotechnology, and biochemistry 86(12) 1658-1669 2022年11月23日

G307S DNAM-1 Mutation Exacerbates Autoimmune Encephalomyelitis via Enhancing CD4+ T Cell Activation.

Rikito Murata, Shota Kinoshita, Kenshiro Matsuda, Atsushi Kawaguchi, Akira Shibuya, Kazuko Shibuya

Journal of immunology (Baltimore, Md. : 1950) 2022年11月2日

Ubiquitin-specific protease TRE17/USP6 promotes tumor cell invasion through the regulation of glycoprotein CD147 intracellular trafficking.

Yukino Ogura, Norihiko Ohbayashi, Yasunori Kanaho, Atsushi Kawaguchi, Yuji Funakoshi

The Journal of biological chemistry 298(9) 102335-102335 2022年9月

ARHGAP1 Transported with Influenza Viral Genome Ensures Integrity of Viral Particle Surface through Efficient Budozone Formation.

Takahiro Kuroki, Tomohisa Hatta, Tohru Natsume, Nobuaki Sakai, Akira Yagi, Kohsuke Kato, Kyosuke Nagata, Atsushi Kawaguchi

mBio 13(3) e0072122 2022年6月28日

TMPRSS2 gene polymorphism common in East Asians confers decreased COVID-19 susceptibility.

Takeshi Sekiya, Yukino Ogura, Hirayasu Kai, Atsushi Kawaguchi, Shino Okawa, Mikako Hirohama, Takahiro Kuroki, Wataru Morii, Akira Hara, Yuji Hiramatsu …

Frontiers in microbiology 13 943877-943877 2022年

Template activating factor-I epigenetically regulates the TERT transcription in human cancer cells.

Kohsuke Kato, Atsushi Kawaguchi, Kyosuke Nagata

Scientific reports 11(1) 17726-17726 2021年9月6日

Arf6 exacerbates allergic asthma through cell-to-cell transmission of ASC inflammasomes.

SangJoon Lee, Akari Ishitsuka, Takahiro Kuroki, Yu-Hsien Lin, Akira Shibuya, Tsunaki Hongu, Yuji Funakoshi, Yasunori Kanaho, Kyosuke Nagata, Atsushi Kawaguchi

JCI insight 6(16) 2021年8月23日

3CL Protease Inhibitors with an Electrophilic Arylketone Moiety as Anti-SARS-CoV-2 Agents.

Sho Konno, Kiyotaka Kobayashi, Miki Senda, Yuta Funai, Yuta Seki, Ikumi Tamai, Laura Schäkel, Kyousuke Sakata, Thanigaimalai Pillaiyar, Akihiro Taguchi …

Journal of medicinal chemistry 65(4) 2926-2939 2021年7月27日

Potent mouse monoclonal antibodies that block SARS-CoV-2 infection

Youjia Guo, Atsushi Kawaguchi, Masaru Takeshita, Takeshi Sekiya, Mikako Hirohama, Akio Yamashita, Haruhiko Siomi, Kensaku Murano

Journal of Biological Chemistry 296 100346-100346 2021年1月

Interaction of influenza A virus NS2/NEP protein with the amino-terminal part of Nup214.

Burçak Şenbaş Akyazi, Ayşegül Pirinçal, Atsushi Kawaguchi, Kyosuke Nagata, Kadir Turan

Turkish journal of biology = Turk biyoloji dergisi 44(2) 82-92 2020年査読有り

Influenza restriction factor MxA functions as inflammasome sensor in the respiratory epithelium

Lee S, Ishitsuka A, Noguchi M, Hirohama M, Fujiyasu Y, Petric PP, Schwemmle M, Staeheli P, Nagata K, Kawaguchi A.

Science Immunology 4(40) eaau4643 2019年10月査読有り最終著者責任著者

Involvement of CTCF in transcription regulation of EGR1 at early G1 phase as an architecture factor

Sekiya T, Kato K, Kawaguchi A, Nagata K