論文

査読有り
2013年

Microfluidic Long-term Cell Culture Platform with Cell-cell Interaction Monitoring Using Surface Acoustic Wave

2013 INTERNATIONAL SYMPOSIUM ON MICRO-NANOMECHATRONICS AND HUMAN SCIENCE (MHS)
  • Atsushi Takano
  • ,
  • Tasuku Kon
  • ,
  • Yasubumi Furuya
  • ,
  • Katsumi Mochitate
  • ,
  • Masato Tanaka
  • ,
  • Nobuyuki Futai

記述言語
英語
掲載種別
研究論文(国際会議プロシーディングス)
出版者・発行元
IEEE

We have developed a poly(dimethylsiloxane) (PDMS)made microfluidic long-term cell culture platform having two cell culture wells with piezoelectric substrate bottom on which shear horizontal surface acoustic wave (SH-SAW) propagates. The SH-SAW propagates on the cells could be used to assay cell-cell and/or cell-surface interaction. The platform also enables optical observation of the cells and acquisition of SH-SAW signals simultaneously. The combination of the on-chip CO2 incubation and SH-SAW-based cell monitoring system successfully detected a long-term change in cell-cell or cell-substrate interaction induced by hydrogen peroxide (H2O2).

リンク情報
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000349834000084&DestApp=WOS_CPL
ID情報
  • ISSN : 2474-378X
  • eISSN : 2474-3798
  • Web of Science ID : WOS:000349834000084

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