論文

査読有り 国際誌
2020年7月

Decreased masticatory performance is related to increased intima-media thickness in a general urban Japanese population: The Suita study.

Journal of prosthodontic research
  • Momoyo Kida
  • ,
  • Takahiro Ono
  • ,
  • Yoshihiro Kokubo
  • ,
  • Yoko Yoshimuta
  • ,
  • Takayuki Kosaka
  • ,
  • Miki Kikui
  • ,
  • Masa-Aki Yamamoto
  • ,
  • Kazunori Ikebe
  • ,
  • Yoshinobu Maeda
  • ,
  • Takashi Nokubi
  • ,
  • Kunihiro Nishimura
  • ,
  • Makoto Watanabe
  • ,
  • Aya Higashiyama
  • ,
  • Yoshihiro Miyamoto

64
3
開始ページ
346
終了ページ
353
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1016/j.jpor.2019.10.001

PURPOSE: The association between periodontal disease and carotid atherosclerosis has been widely discussed, but to our knowledge, no population-based studies have been conducted on the association between masticatory ability and carotid atherosclerosis. We aimed to clarify the hypothesis that objectively accessed masticatory performance is related to increased intima-media thickness (IMT) in a general urban population. METHODS: We studied 1,484 Japanese (mean age: 66.9 y) from the Suita study. Masticatory performance was measured using test gummy jelly, and periodontal status was evaluated using the Community Periodontal Index (CPI). Carotid ultrasonography was performed to measure maximum IMT (max-IMT) in the entire area of the carotid arteries. Analysis of covariance was used to compare max-IMT according to quartiles of masticatory performance adjusted by cardiovascular risk factors and periodontal status. RESULTS: Multivariable-adjusted max-IMT (standard error) was significantly higher in the lowest masticatory performance quartile group (decreased group) (1.58 ± 0.03 and 1.44 ± 0.03 mm) than in the 2nd to 4th quartiles combined (non-decreased groups) in both sexes (1.48 ± 0.02 mm, trend P = 0.038) and in women (1.34 ± 0.02 mm, trend P = 0.013), respectively. In participants without cardiovascular risk factors (n = 250), multivariable-adjusted max-IMT was significantly higher in the decreased (1.54 ± 0.06, 2.08 ± 0.22, and 1.42 ± 0.06 mm) than in the non-decreased groups in both sexes (1.31 ± 0.04 mm, trend P = 0.006), in men (1.41 ± 0.12 mm, trend P = 0.028), and in women (1.28 ± 0.04 mm, trend P = 0.073). CONCLUSIONS: These findings suggest that decreased masticatory performance may be related to carotid IMT progression in the general urban Japanese population.

リンク情報
DOI
https://doi.org/10.1016/j.jpor.2019.10.001
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/32199803

エクスポート
BibTeX RIS