Ayako Nakajima

Profile Information

Affiliation: 教授, 三重大学医学部附属病院リウマチ・膠原病センター, 三重大学大学院医学系研究科臨床医学系講座リウマチ膠原病内科学

Contact information: ayakonkjclin.medic.mie-u.ac.jp
Researcher number: 90211432
J-GLOBAL ID: 202001001048207947
researchmap Member ID: R000000450

Research Areas

Life sciences / Allergies and connective tissue disease /

Research History

Sep, 2017 - Present

Professor, Center for Rheumatic Diseases, Mie University Hospital, Division of Rheumatology, Mie University Graduate School of Medicine

Education

Apr, 1980 - Mar, 1986

Faculty of Medicine, Mie University

Papers

Geographic variations in rheumatoid arthritis treatment in Japan: A nationwide retrospective study using the national database of health insurance claims and specific health checkups of Japan.

Ayako Nakajima, Ryoko Sakai, Eisuke Inoue, Masayoshi Harigai

Modern rheumatology, 1-9, Apr 15, 2021
Prevalence of patients with rheumatoid arthritis and age-stratified trends in clinical characteristics and treatment, based on the National Database of Health Insurance Claims and Specific Health Checkups of Japan.

Ayako Nakajima, Ryoko Sakai, Eisuke Inoue, Masayoshi Harigai

International journal of rheumatic diseases, Oct 5, 2020
リウマチ性疾患の疫学ナショナルデータベースを用いた全国の関節リウマチ患者数の推定

中島亜矢子, 酒井良子, 井上永介, 針谷正祥

日本リウマチ学会総会・学術集会プログラム・抄録集, 64回 406-406, Aug, 2020
リウマチ性疾患の疫学ナショナルデータベースを用いた高齢関節リウマチ患者の処方実態に関する検討

酒井良子, 井上永介, 中島亜矢子, 針谷正祥

日本リウマチ学会総会・学術集会プログラム・抄録集, 64回 409-409, Aug, 2020
A large observational cohort study of rheumatoid arthritis, IORRA: Providing context for today's treatment options.

Hisashi Yamanaka, Eiichi Tanaka, Ayako Nakajima, Takefumi Furuya, Katsunori Ikari, Atsuo Taniguchi, Eisuke Inoue, Masayoshi Harigai

Modern rheumatology, 30(1) 1-6, Jan, 2020 Peer-reviewed
Factors associated with decreasing serum 25(OH)D among Japanese patients with rheumatoid arthritis: Results from the IORRA cohort study.

Masanori Nakayama, Takefumi Furuya, Eisuke Inoue, Eiichi Tanaka, Katsunori Ikari, Ayako Nakajima, Atsuo Taniguchi, Hisashi Yamanaka

Modern rheumatology, 29(3) 430-435, May, 2019 Peer-reviewed
Japan College of Rheumatology guideline for the use of methotrexate in patients with rheumatoid arthritis.

Hideto Kameda, Takao Fujii, Ayako Nakajima, Ryuji Koike, Akira Sagawa, Katsuaki Kanbe, Tetsuya Tomita, Masayoshi Harigai, Yasuo Suzuki

Modern rheumatology, 29(1) 31-40, Jan, 2019 Peer-reviewed
Reduction of methotrexate and glucocorticoids use after the introduction of biological disease-modifying anti-rheumatic drugs in patients with rheumatoid arthritis in daily practice based on the IORRA cohort.

Yoko Shimizu, Eiichi Tanaka, Eisuke Inoue, Kumi Shidara, Naoki Sugimoto, Yohei Seto, Ayako Nakajima, Shigeki Momohara, Atsuo Taniguchi, Hisashi Yamanaka

Modern rheumatology, 28(3) 461-467, May, 2018 Peer-reviewed
Incidence of comprehensive hospitalization due to infection, cardiovascular disease, fractures, and malignancies in patients with rheumatoid arthritis.

Naoki Sugimoto, Ayako Nakajima, Eisuke Inoue, Kumi Shidara, Hiroyuki Yamashita, Akio Mimori, Hitoshi Tokuda, Yohei Seto, Eiichi Tanaka, Shigeki Momohara, Atsuo Taniguchi, Hisashi Yamanaka

Rheumatology international, 37(11) 1871-1878, Nov, 2017 Peer-reviewed
Characteristics and risk factors of lymphoproliferative disorders among patients with rheumatoid arthritis concurrently treated with methotrexate: a nested case-control study of the IORRA cohort.

Yoko Shimizu, Ayako Nakajima, Eisuke Inoue, Kumi Shidara, Naoki Sugimoto, Yohei Seto, Eiichi Tanaka, Shigeki Momohara, Atsuo Taniguchi, Hisashi Yamanaka

Clinical rheumatology, 36(6) 1237-1245, Jun, 2017 Peer-reviewed
The minimally important difference for the Japanese version of the health assessment questionnaire in patients with rheumatoid arthritis in daily practice.

Kumi Shidara, Ayako Nakajima, Eisuke Inoue, Daisuke Hoshi, Naoki Sugimoto, Yohei Seto, Eiichi Tanaka, Katsunori Ikari, Atsuo Taniguchi, Hisashi Yamanaka

Modern rheumatology, 27(3) 430-434, May, 2017 Peer-reviewed
Pharmacoeconomic analysis of biological disease modifying antirheumatic drugs in patients with rheumatoid arthritis based on real-world data from the IORRA observational cohort study in Japan.

Eiichi Tanaka, Eisuke Inoue, Rei Yamaguchi, Yoko Shimizu, Akiko Kobayashi, Naoki Sugimoto, Daisuke Hoshi, Kumi Shidara, Eri Sato, Yohei Seto, Ayako Nakajima, Shigeki Momohara, Atsuo Taniguchi, Hisashi Yamanaka

Modern rheumatology, 27(2) 227-236, Mar, 2017 Peer-reviewed
Continual Maintenance of Remission Defined by the ACR/EULAR Criteria in Daily Practice Leads to Better Functional Outcomes in Patients with Rheumatoid Arthritis.

Kumi Shidara, Ayako Nakajima, Eisuke Inoue, Daisuke Hoshi, Naoki Sugimoto, Yohei Seto, Eiichi Tanaka, Shigeki Momohara, Atsuo Taniguchi, Hisashi Yamanaka

The Journal of rheumatology, 44(2) 147-153, Feb, 2017 Peer-reviewed
Effectiveness of tacrolimus in comparison with methotrexate or biologics in propensity score-matched patients with rheumatoid arthritis.

Ayako Nakajima, Eisuke Inoue, Atsuo Taniguchi, Shigeki Momohara, Hisashi Yamanaka

Modern rheumatology, 26(6) 836-843, Nov, 2016 Peer-reviewed
[Cardiovascular diseases in rheumatoid arthritis].

Ayako Nakajima

Nihon rinsho. Japanese journal of clinical medicine, 74(6) 1012-6, Jun, 2016 Invited
Profiles of EQ-5D utility scores in the daily practice of Japanese patients with rheumatoid arthritis; Analysis of the IORRA database.

Daisuke Hoshi, Eiichi Tanaka, Ataru Igarashi, Eisuke Inoue, Akiko Kobayashi, Naoki Sugimoto, Kumi Shidara, Eri Sato, Yohei Seto, Ayako Nakajima, Shigeki Momohara, Atsuo Taniguchi, Kiichiro Tsutani, Hisashi Yamanaka

Modern rheumatology, 26(1) 40-5, 2016 Peer-reviewed
Assessment of the effectiveness of golimumab 50-mg and 100-mg regimens in patients with rheumatoid arthritis in daily practice.

Eri Sato, Eiichi Tanaka, Ayako Nakajima, Eisuke Inoue, Yoko Shimizu, Rei Yamaguchi, Moeko Ochiai, Kumi Shidara, Daisuke Hoshi, Naoki Sugimoto, Yohei Seto, Atsuo Taniguchi, Shigeki Momohara, Hisashi Yamanaka

Modern rheumatology, 25(4) 528-33, Jul, 2015 Peer-reviewed
Cost-effectiveness of tocilizumab, a humanized anti-interleukin-6 receptor monoclonal antibody, versus methotrexate in patients with rheumatoid arthritis using real-world data from the IORRA observational cohort study.

Eiichi Tanaka, Eisuke Inoue, Daisuke Hoshi, Yoko Shimizu, Akiko Kobayashi, Naoki Sugimoto, Kumi Shidara, Eri Sato, Yohei Seto, Ayako Nakajima, Shigeki Momohara, Atsuo Taniguchi, Hisashi Yamanaka

Modern rheumatology, 25(4) 503-13, Jul, 2015 Peer-reviewed
Incidence of herpes zoster in Japanese patients with rheumatoid arthritis from 2005 to 2010.

Ayako Nakajima, Wako Urano, Eisuke Inoue, Atsuo Taniguchi, Shigeki Momohara, Hisashi Yamanaka

Modern rheumatology, 25(4) 558-61, Jul, 2015 Peer-reviewed
Effect of Smoking on Remission Proportions Differs Between Male and Female Patients with Rheumatoid Arthritis: A Study Based on the IORRA Survey.

Yasushi Inoue, Ayako Nakajima, Eiichi Tanaka, Eisuke Inoue, Akiko Kobayashi, Daisuke Hoshi, Naoki Sugimoto, Yohei Seto, Atsuo Taniguchi, Shigeki Momohara, Hisashi Yamanaka

The Journal of rheumatology, 42(7) 1083-9, Jul, 2015 Peer-reviewed

Misc.

Factors Associated with Worsening Serum Vitamin D Deficiencies in Japanese Patients with Rheumatoid Arthritis: Results from the IORRA Cohort Study

Masanori Nakayama, Takefumi Furuya, Eisuke Inoue, Eiichi Tanaka, Katsunori Ikari, Ayako Nakajima, Atsuo Taniguchi, Hisashi Yamanaka

ARTHRITIS & RHEUMATOLOGY, 69, Oct, 2017
Gingival Bleeding and Periodontitis in Japanese Patients with Rheumatoid Arthritis: Results from the IORRA Cohort Study

Takefumi Furuya, Eisuke Inoue, Shigeru Maeda, Eiichi Tanaka, Katsunori Ikari, Ayako Nakajima, Atsuo Taniguchi, Hisashi Yamanaka

ARTHRITIS & RHEUMATOLOGY, 69, Oct, 2017
Fatigue Is Strongly Associated with the Patient Global Assessment and May Affect Disease Severity and Clinical Remission in Patients with Rheumatoid Arthritis: A Cross-Sectional Study from IORRA, a Large Observational Cohort of Japanese Rheumatoid Arthritis Patients

Naoki Sugimoto, Eiichi Tanaka, Eisuke Inoue, Kumiko Saka, Eri Sugano, Naohiro Sugitani, Moeko Ochiai, Yoko Shimizu, Rei Yamaguchi, Katsunori Ikari, Ayako Nakajima, Atsuo Taniguchi, Hisashi Yamanaka

ARTHRITIS & RHEUMATOLOGY, 69, Oct, 2017
Biologic Disease-Modifying Anti-Rheumatic Drug Use and the Risk of Non-Vertebral Osteoporotic Fractures in Japanese Patients with Rheumatoid Arthritis: Results from the IORRA Cohort Study

Takefumi Furuya, Eisuke Inoue, Masanori Nakayama, Eiichi Tanaka, Katsunori Ikari, Ayako Nakajima, Atsuo Taniguchi, Hisashi Yamanaka

ARTHRITIS & RHEUMATOLOGY, 68, Oct, 2016
Trends in the Occurrence of Malignancy in Japanese Patients with Rheumatoid Arthritis Based on the Institute of Rheumatology, Rheumatoid Arthritis (IORRA) Cohort during a 14-Year Observation Period

Naoki Sugimoto, Eiichi Tanaka, Eisuke Inoue, Moeko Ochiai, Yoko Shimizu, Rei Yamaguchi, Kumi Shidara, Ayako Nakajima, Atsuo Taniguchi, Hisashi Yamanaka

ARTHRITIS & RHEUMATOLOGY, 68, Oct, 2016
Cardiovascular diseases in rheumatoid arthritis

74(6) 1012-1016, Jun, 2016
Trajectories of EQ-5D in RA Patients Treated with Biologics Using the IORRA Cohort

Daisuke Hoshi, Eiichi Tanaka, Eisuke Inoue, Yoko Shimizu, Naoki Sugimoto, Kumi Shidara, Ayako Nakajima, Shigeki Momohara, Atsuo Taniguchi, Hisashi Yamanaka

ARTHRITIS & RHEUMATOLOGY, 67, Oct, 2015
Minimally Important Difference in the European Quality of Life-Five Dimensions in Patients with Rheumatoid Arthritis.

Daisuke Hoshi, Eiichi Tanaka, Eisuke Inoue, Kumi Shidara, Yoko Shimizu, Akiko Kobayashi, Naoki Sugimoto, Eri Sato, Yohei Seto, Ayako Nakajima, Shigeki Momohara, Atsuo Taniguchi, Hisashi Yamanaka

ARTHRITIS & RHEUMATOLOGY, 66 S183-S184, Oct, 2014
Discontinuation of Biologics in Patients with Rheumatoid Arthritis after Achieving Low-Activity Disease Status

Moeko Ochiai, Eri Sato, Eiichi Tanaka, Eisuke Inoue, Ayako Nakajima, Shigeki Momohara, Atsuo Taniguchi, Hisashi Yamanaka

ARTHRITIS & RHEUMATOLOGY, 66 S213-S214, Oct, 2014
Functional Disability and Quality Of Life Are More Likely Improved In Patients With Rheumatoid Arthritis Who Achieved The New ACR/EULAR Remission Criteria Compared To DAS28 Remission In Daily Practice.

Yoko Shimizu, Ayako Nakajima, Eisuke Inoue, Eiichi Tanaka, Akiko Kobayashi, Yohei Seto, Shigeki Momohara, Atsuo Taniguchi, Hisashi Yamanaka

ARTHRITIS AND RHEUMATISM, 65 S566-S566, Oct, 2013
Optimal Rheumatoid Arthritis Patient Selection For Biological Treatment From Pharmacoeconomic Perspectives Based On The Institute Of Rheumatology, Rheumatoid Arthritis (IORRA) Cohort.

Eiichi Tanaka, Eisuke Inoue, Yoko Shimizu, Akiko Kobayashi, Naoki Sugimoto, Daisuke Hoshi, Kumi Shidara, Eri Sato, Yohei Seto, Ayako Nakajima, Shigeki Momohara, Atsuo Taniguchi, Hisashi Yamanaka

ARTHRITIS AND RHEUMATISM, 65 S568-S568, Oct, 2013
座談会 RAの新寛解基準

針谷正祥, 中島亜矢子, 岸本暢将

Frontiers in rheumatology & clinical immunology, 6(4) 175-185, Nov, 2012
Analysis of Factors Impact On Patient Global Assessment in Daily Practice Based On Observational Cohort IORRA (Institute of Rheumatology, Rheumatoid Arthritis)

Yasushi Inoue, Eiichi Tanaka, Ayako Nakajima, Eisuke Inoue, Akiko Kobayashi, Daisuke Hoshi, Naoki Sugimoto, Kumi Shidara, Yohei Seto, Atsuo Taniguchi, Shigeki Momohara, Hisashi Yamanaka

ARTHRITIS AND RHEUMATISM, 64(10) S171-S171, Oct, 2012
Prevalence and Associated Factors of Vitamin D Insufficiency and Deficiency in 4,793 Japanese Patients with Rheumatoid Arthritis.

Takefumi Furuya, Takayuki Hosoi, Eiichi Tanaka, Ayako Nakajima, Atsuo Taniguchi, Shigeki Momohara, Hisashi Yamanaka

ARTHRITIS AND RHEUMATISM, 64(10) S829-S829, Oct, 2012
Evaluation of the Cost-Effectiveness of Rheumatoid Arthritis Treatment with Biologic Agents Using the IORRA Cohort Database

Eiichi Tanaka, Eisuke Inoue, Daisuke Hoshi, Akiko Kobayashi, Naoki Sugimoto, Kumi Shidara, Eri Sato, Yasushi Inoue, Yohei Seto, Ayako Nakajima, Shigeki Momohara, Atsuo Taniguchi, Hisashi Yamanaka

ARTHRITIS AND RHEUMATISM, 64(10) S779-S779, Oct, 2012
High Patient Global Assessment Scores Associate with the Residual Disease Activity Unidentified by a 28-Joint Examination in Rheumatoid Arthritis Patients Approaching Clinical Remission

Yasushi Inoue, Eiichi Tanaka, Ayako Nakajima, Eisuke Inoue, Akiko Kobayashi, Daisuke Hoshi, Naoki Sugimoto, Kumi Shidara, Yohei Seto, Atsuo Taniguchi, Shigeki Momohara, Hisashi Yamanaka

ARTHRITIS AND RHEUMATISM, 64(10) S175-S175, Oct, 2012
Greater Physical Dysfunction Is a Negative Predictor for Achieving Boolean-Based Remission in Patients with Rheumatoid Arthritis Treated with Tocilizumab

Daisuke Hoshi, Kumi Shidara, Yohei Seto, Eiichi Tanaka, Ayako Nakajima, Shigeki Momohara, Atsuo Taniguchi, Hisashi Yamanaka

ARTHRITIS AND RHEUMATISM, 63(10) S482-S483, Oct, 2011
No Evidence of Increased Mortality in Rheumatoid Arthritis Patients Treated with Biologics: Results From a Multicenter Cohort in Japan

Ayako Nakajima, Toshihisa Kojima, Wataru Fukuda, Taku Yoshio, Eisuke Inoue, Koichi Amano, Seiji Minota, Kazuyoshi Saito, Shigeki Momohara, Naoki Ishiguro, Yoshiya Tanaka, Tsutomu Takeuchi, Hisashi Yamanaka

ARTHRITIS AND RHEUMATISM, 63(10) S466-S467, Oct, 2011
Discrepancy Between Boolean Remission and DAS28 Remission Is Dependent on the Differences in Number of Swollen Joints and Patient Global Assessment in Daily Practice, Based on the Institute of Rheumatology, Rheumatoid Arthritis (IORRA) Cohort

Eiichi Tanaka, Kumi Shidara, Eisuke Inoue, Yohei Seto, Ayako Nakajima, Atsuo Taniguchi, Shigeki Momohara, Hisashi Yamanaka

ARTHRITIS AND RHEUMATISM, 63(10) S126-S126, Oct, 2011
Successful Maintenance of Remission Defined by the New ACR/EULAR Criteria Leads to Better Functional Outcomes in Rheumatoid Arthritis in Daily Practice, Especially in Patients with Early RA, Based on the Institute of Rheumatology, Rheumatoid Arthritis (IORRA) Cohort

Kumi Shidara, Eiichi Tanaka, Eisuke Inoue, Yohei Seto, Ayako Nakajima, Shigeki Momohara, Atsuo Taniguchi, Hisashi Yamanaka

ARTHRITIS AND RHEUMATISM, 63(10) S124-S124, Oct, 2011

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慢性関節リウマチにおける生体的活性化T細胞の解析-体細胞突然変異を指標とした検討

科学研究費助成事業奨励研究(A), 日本学術振興会, 1996 - 1996

中島亜矢子
滑膜細胞、T細胞およびB細胞のクローニングによる抗リウマチ作用機序の検討

科学研究費助成事業奨励研究(A), 日本学術振興会, 1994 - 1994

中島亜矢子

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