論文

査読有り 国際誌
2020年4月

Dynamic gating window technique for the reduction of dosimetric error in respiratory-gated spot-scanning particle therapy: An initial phantom study using patient tumor trajectory data.

Journal of applied clinical medical physics
  • Naoki Miyamoto
  • ,
  • Kouhei Yokokawa
  • ,
  • Seishin Takao
  • ,
  • Taeko Matsuura
  • ,
  • Sodai Tanaka
  • ,
  • Shinichi Shimizu
  • ,
  • Hiroki Shirato
  • ,
  • Kikuo Umegaki

21
4
開始ページ
13
終了ページ
21
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1002/acm2.12832

Spot-scanning particle therapy possesses advantages, such as high conformity to the target and efficient energy utilization compared with those of the passive scattering irradiation technique. However, this irradiation technique is sensitive to target motion. In the current clinical situation, some motion management techniques, such as respiratory-gated irradiation, which uses an external or internal surrogate, have been clinically applied. In surrogate-based gating, the size of the gating window is fixed during the treatment in the current treatment system. In this study, we propose a dynamic gating window technique, which optimizes the size of gating window for each spot by considering a possible dosimetric error. The effectiveness of the dynamic gating window technique was evaluated by simulating irradiation using a moving target in a water phantom. In dosimetric characteristics comparison, the dynamic gating window technique exhibited better performance in all evaluation volumes with different effective depths compared with that of the fixed gate approach. The variation of dosimetric characteristics according to the target depth was small in dynamic gate compared to fixed gate. These results suggest that the dynamic gating window technique can maintain an acceptable dose distribution regardless of the target depth. The overall gating efficiency of the dynamic gate was approximately equal or greater than that of the fixed gating window. In dynamic gate, as the target depth becomes shallower, the gating efficiency will be reduced, although dosimetric characteristics will be maintained regardless of the target depth. The results of this study suggest that the proposed gating technique may potentially improve the dose distribution. However, additional evaluations should be undertaken in the future to determine clinical applicability by assuming the specifications of the treatment system and clinical situation.

リンク情報
DOI
https://doi.org/10.1002/acm2.12832
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/32068347
PubMed Central
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170289
ID情報
  • DOI : 10.1002/acm2.12832
  • PubMed ID : 32068347
  • PubMed Central 記事ID : PMC7170289

エクスポート
BibTeX RIS