2019年7月
Three-dimensional fine structure of feeder organelle in Cryptosporidium parvum.
Parasitology international
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- 巻
- 73
- 号
- 開始ページ
- 101958
- 終了ページ
- 101958
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1016/j.parint.2019.101958
Feeder organelles of Cryptosporidium are the convoluted structures located at the host-parasite interface that uptake of nutrients from host cells. Although the ultrastructure of feeder organelles has been summarized as being highly invaginated structure, the three-dimensional form remains uncertain. Osmium-maceration scanning electron microscopy (OS-SEM) allows visualization of the three-dimensional ultrastructure after removing soluble proteins. Here, we assessed C. parvum attached to mouse ileal epithelial cells using transmission electron microscopy (TEM) and OS-SEM. Feeder organelles visualized by TEM as aggregated structures of concentrically-, vertically- and randomly-lined bars comprised a complex reticulated network of stacked flat bursiform, ring-shaped bursiform and reticulated tubular membranes on OS-SEM. These findings suggested that the feeder organelles are more complex than was previously thought.
- リンク情報
- ID情報
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- DOI : 10.1016/j.parint.2019.101958
- ISSN : 1383-5769
- ORCIDのPut Code : 70987620
- PubMed ID : 31299356