論文

査読有り 筆頭著者 国際誌
2019年7月

Three-dimensional fine structure of feeder organelle in Cryptosporidium parvum.

Parasitology international
  • Bochimoto H
  • ,
  • Kondoh D
  • ,
  • Ishihara Y
  • ,
  • Kabir MHB
  • ,
  • Kato K

73
開始ページ
101958
終了ページ
101958
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1016/j.parint.2019.101958

Feeder organelles of Cryptosporidium are the convoluted structures located at the host-parasite interface that uptake of nutrients from host cells. Although the ultrastructure of feeder organelles has been summarized as being highly invaginated structure, the three-dimensional form remains uncertain. Osmium-maceration scanning electron microscopy (OS-SEM) allows visualization of the three-dimensional ultrastructure after removing soluble proteins. Here, we assessed C. parvum attached to mouse ileal epithelial cells using transmission electron microscopy (TEM) and OS-SEM. Feeder organelles visualized by TEM as aggregated structures of concentrically-, vertically- and randomly-lined bars comprised a complex reticulated network of stacked flat bursiform, ring-shaped bursiform and reticulated tubular membranes on OS-SEM. These findings suggested that the feeder organelles are more complex than was previously thought.

リンク情報
DOI
https://doi.org/10.1016/j.parint.2019.101958
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/31299356
URL
http://europepmc.org/abstract/med/31299356
ID情報
  • DOI : 10.1016/j.parint.2019.101958
  • ISSN : 1383-5769
  • ORCIDのPut Code : 70987620
  • PubMed ID : 31299356

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