論文

査読有り
2010年6月

Cytoskeleton-modulating effectors of enteropathogenic and enterohemorrhagic Escherichia coli: a case for EspB as an intrinsically less-ordered effector

FEBS JOURNAL
  • Daizo Hamada
  • ,
  • Mitsuhide Hamaguchi
  • ,
  • Kayo N. Suzuki
  • ,
  • Ikuhiro Sakata
  • ,
  • Itaru Yanagihara

277
11
開始ページ
2409
終了ページ
2415
記述言語
英語
掲載種別
DOI
10.1111/j.1742-4658.2010.07655.x
出版者・発行元
WILEY-BLACKWELL

Enterohemorrhagic and enteropathogenic Escherichia coli produce various effector proteins that are directly injected into the host-cell cytosol through the type III secretion system. E. coli secreted protein (Esp)B is one such effector protein, and affects host-cell morphology by reorganizing actin networks. Unlike most globular proteins that have well-ordered, rigid structures, the structures of type III secretion system effectors from pathogenic Gram-negative bacteria, including EspB, are often less well-ordered. This minireview focuses on the functional relationship between the structural properties of these proteins and their roles in type III secretion system-associated pathogenesis.

Web of Science ® 被引用回数 : 13

リンク情報
DOI
https://doi.org/10.1111/j.1742-4658.2010.07655.x
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/20477867
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000277800600004&DestApp=WOS_CPL

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