チェクミンフェイ (Min Fey Chek) - マイポータル

基本情報

学位: 博士(奈良先端科学技術大学院大学)
MSc(Universiti Sains Malaysia)
BSc(Universiti Sains Malaysia)

通称等の別名: Adrian
研究者番号: 60834455
J-GLOBAL ID: 201801014600649050
researchmap会員ID: B000314017

外部リンク: http://bsw3.naist.jp/hako/?cate=213

研究キーワード

研究分野

経歴

2023年8月 - 現在

奈良先端科学技術大学院大学, 先端科学技術研究科・バイオサイエンス領域・環境微生物学研究室 / (兼)研究推進機構・蛋白質工学研究室, 助教
2021年4月 - 2023年7月

奈良先端科学技術大学院大学, 蛋白質工学研究室（箱嶋研究室), 特任助教
2017年10月 - 2021年3月

Nara Institute of Science and Technology (NAIST), Postdoctoral Fellow

学歴

2013年10月 - 2017年9月

Nara Institute of Science and Technology (NAIST), Graduate School of Biological Sciences, PhD
2010年1月 - 2013年9月

Universiti Sains Malaysia (USM), School of Biological Sciences, Master of Science (MSc)
2006年9月 - 2009年9月

Universiti Sains Malaysia (USM), School of Biological Sciences, Bachelor of Science (BSc)

受賞

2025年9月

第22回梅園賞, Structural Insights Into the Catalytic Mechanism and Functional Regions of PHA synthase, 奈良先端科学技術大学院大学

チェクミンフェイ
2019年8月

Young Scientist Program, 27th FAOBMB-44th MSBMB Conference, Kuala Lumpur, Malaysia

謝銘輝
2017年7月

Travel Award, The Protein Society’s 31st annual symposium

謝銘輝
2017年5月

Best Poster Award (Silver Medal), The 6th International Conference on Bio-based Polymers (ICBP)

謝銘輝
2013年10月

MEXT PhD Scholarship recipient (2013-2017), Japanese Government (MONBUKAGAKUSHO:MEXT)

謝銘輝
2011年2月

USM fellowship recipient (2011-2013), Universiti Sains Malaysia (USM)

謝銘輝

論文

Structure of the C-terminal of Viral Responsive Protein 15 (VRP15): A Key Protein During White Spot Syndrome Virus (WSSV) Infection.

Pasunee Laohawutthichai, Sun-Yong Kim, Min Fey Chek, Thapanan Jatuyosporn, Anchalee Tassanakajon, Kuakarun Krusong, Toshio Hakoshima

Journal of molecular biology 437(19) 169329-169329 2025年10月1日
Adipocytes promote cancer stemness properties in oral squamous cell carcinoma through C3/C3AR axis and sphingolipid metabolism.

Tian Xu Qin, Ying Ying Zhu, Wai Hoe Ng, Siew Kit Ng, Min Fey Chek, Kai Dun Tang

Cancer letters 628 217848-217848 2025年9月28日
Engineering chimeric polyhydroxyalkanoate synthases for enhanced copolymerization of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate): A promising biotechnological approach.

Hua Tiang Tan, Yiming Lei, Min Fey Chek, Manying He, Kah Chee Pow, Sixu Gong, Quan Hao, Toshio Hakoshima, Kumar Sudesh, Gaowen Liu

Bioresource technology 439 133307-133307 2025年9月10日
Mediator Complex Subunit 27-Enriched Small Extracellular Vesicles Mediate the Crosstalk between Periodontal Bacteria and HPV-Driven Head and Neck Cancer.

Tian Xu Qin, Wai Hoe Ng, Siew Kit Ng, Ying Ying Zhu, Min Fey Chek, Kai Dun Tang

Journal of proteome research 24(9) 4689-4698 2025年9月5日
Proteomic and transcriptomic profiling in exosomes derived from HPV-positive head and neck cancer.

Tian Xu Qin, Wai Hoe Ng, Min Fey Chek, Kai Dun Tang

Biochemical and biophysical research communications 776 152188-152188 2025年8月30日
Structural basis of a GatC ortholog transporter in the bacterial phosphotransferase system.

Yutaro S Takahashi, Hidetaka Kohga, Min Fey Chek, Kotomi Yamamoto, Jun F Takahashi, Hideki Shigematsu, Yoshiki Tanaka, Muneyoshi Ichikawa, Ryoji Miyazaki, Toshio Hakoshima …

FEBS letters 599(16) 2377-2387 2025年8月
NF-kappa-B inhibitor alpha mediates cancer stemness characteristics in oral squamous cell carcinoma by interacting with cathepsin B.

Tian Xu Qin, Ying Ying Zhu, Wai Hoe Ng, Siew Kit Ng, Min Fey Chek, Kai Dun Tang

International journal of biological macromolecules 311(Pt 2) 143690-143690 2025年4月30日
Structures of Polyhydroxyalkanoate Synthase PhaC from Aeromonas caviae, Producing Biodegradable Plastics.

Min Fey Chek, Sun-Yong Kim, Tomoyuki Mori, Keiji Matsumoto, Shunsuke Sato, Toshio Hakoshima

Angewandte Chemie (International ed. in English) 64(26) e202504626 2025年4月25日
N-terminal truncation of PhaCBP-M-CPF4 and its effect on PHA production.

Soon Zher Neoh, Hua Tiang Tan, Chanaporn Trakunjae, Min Fey Chek, Pilanee Vaithanomsat, Toshio Hakoshima, Kumar Sudesh

Microbial cell factories 23(1) 52-52 2024年2月15日
The SH3 binding site in front of the WH1 domain contributes to the membrane binding of the BAR domain protein endophilin A2.

Pei Fang Sim, Min Fey Chek, Nhung Thi Hong Nguyen, Tamako Nishimura, Takehiko Inaba, Toshio Hakoshima, Shiro Suetsugu

Journal of biochemistry 2023年10月9日
Small GTPase Cdc42, WASP, and scaffold proteins for higher-order assembly of the F-BAR domain protein.

Wan Nurul Izzati Wan Mohamad Noor, Nhung Thi Hong Nguyen, Theng Ho Cheong, Min Fey Chek, Toshio Hakoshima, Takehiko Inaba, Kyoko Hanawa-Suetsugu, Tamako Nishimura, Shiro Suetsugu

Science advances 9(17) eadf5143 2023年4月28日査読有り
Characterization of the polyhydroxyalkanoate (PHA) synthase from Ideonella sakaiensis, a bacterium that is capable of degrading and assimilating poly(ethylene terephthalate)

Hua Tiang Tan, Min Fey Chek, Soon Zher Neoh, Shaik Ling Ang, Shosuke Yoshida, Toshio Hakoshima, Kumar Sudesh

POLYMER DEGRADATION AND STABILITY 206 2022年12月査読有り
Characterization of an (R)-specific enoyl-CoA hydratase from Streptomyces sp. strain CFMR 7: A metabolic tool for enhancing the production of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate).

Hua Tiang Tan, Min Fey Chek, Yuki Miyahara, Sun-Yong Kim, Takeharu Tsuge, Toshio Hakoshima, Kumar Sudesh

Journal of bioscience and bioengineering 2022年8月8日査読有り
Polyhydroxyalkanoate synthase (PhaC): The key enzyme for biopolyester synthesis

Soon Zher Neoh, Min Fey Chek, Hua Tiang Tan, Javier A. Linares-Pastén, Ardra Nandakumar, Toshio Hakoshima, Kumar Sudesh

Current Research in Biotechnology 4 87-101 2022年査読有り招待有り
Crystal structure of N-terminal degron-truncated human glutamine synthetase.

Min Fey Chek, Sun Yong Kim, Tomoyuki Mori, Hisayuki Kojima, Toshio Hakoshima

Acta crystallographica. Section F, Structural biology communications 77(Pt 11) 427-434 2021年11月1日査読有り筆頭著者
Identification of regions affecting enzyme activity, substrate binding, dimer stabilization and polyhydroxyalkanoate (PHA) granule morphology in the PHA synthase of Aquitalea sp. USM4.

Hui Lim, Jo-Ann Chuah, Min Fey Chek, Hua Tiang Tan, Toshio Hakoshima, Kumar Sudesh

International journal of biological macromolecules 186 414-423 2021年7月8日査読有り
Structural insights into vesicle amine transport-1 (VAT-1) as a member of the NADPH-dependent quinone oxidoreductase family.

Sun-Yong Kim, Tomoyuki Mori, Min Fey Chek, Shunji Furuya, Ken Matsumoto, Taisei Yajima, Toshihiko Ogura, Toshio Hakoshima

Scientific reports 11(1) 2120-2120 2021年1月22日査読有り
Evaluation of BP-M-CPF4 polyhydroxyalkanoate (PHA) synthase on the production of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) from plant oil using Cupriavidus necator transformants

Hua Tiang Tan, Min Fey Chek, Manoj Lakshmanan, Choon Pin Foong, Toshio Hakoshima, Kumar Sudesh

International Journal of Biological Macromolecules 159 250-257 2020年9月査読有り
Asymmetric Open-Closed Dimer Mechanism of Polyhydroxyalkanoate Synthase PhaC

Min Fey Chek, Sun-Yong Kim, Tomoyuki Mori, Hua Tiang Tan, Kumar Sudesh, Toshio Hakoshima

iScience 23(5) 101084-101084 2020年5月査読有り筆頭著者
PHA synthase (PhaC): interpreting the functions of bioplastic-producing enzyme from a structural perspective

Chek MF, Hiroe A, Hakoshima T, Sudesh K, Taguchi S

Applied Microbiology and Biotechnology 103(3) 1131-1141 2019年2月査読有り筆頭著者

もっとみる

書籍等出版物

Enzymatic Polymerization towards Green Polymer Chemistry. Chapter 7: Synthesis of Polyesters III: Acyltransferase as Catalyst

Hiroe A, Chek MF, Hakoshima T, Sudesh K, Taguchi S (担当:分担執筆)

Springer Singapore 2019年 (ISBN: 9789811338137)

講演・口頭発表等

"Crystal structure of bioplastic-synthesizing PHA synthase (PhaC) revealing an unexpected open-closed heterodimer"

CHEK Min Fey

the 47th International Congress on Science, Technology and Technology-based Innovation (STT47) 2021年10月5日 The Science Society of Thailand 招待有り
Crystal structure of PHA synthase and the unexpected open-closed heterodimer

CHEK MIN FEY

ISBP 2021 Webinar series 2021年5月20日招待有り
Structural and functional insight into the bioplastic-producing enzyme - PHA synthase

チェクミンフェイ

27th FAOBMB & 44th MSBMB Conference 2019 2019年8月19日
Structural and functional insight into the bioplastic-producing enzyme - PHA synthase

チェクミンフェイ

Young Scientist Program, IUBMB in conjunction with 27th FAOBMB & 44th MSBMB Conference 2019 2019年8月16日招待有り
Structural studies of the catalytic domain of PHA synthase from Chromobacterium sp. USM2

謝銘輝

The 10th International Conference of Modification, Degradation and Stabilization of Polymers (MoDeSt208) 2018年9月3日
Structural studies of the catalytic domain of PHA synthase from Chromobacterium sp. USM2

謝銘輝

The 3rd International Symposium & Workshop on Functional Genomics and Structural Biology 2018年7月24日
922

A closed conformation of the catalytic domain of PHA synthase from Chromobacterium sp. USM2

謝銘輝

The Protein Society's 31st Annual Symposium 2017 2017年7月24日
A closed conformation of the catalytic domain of PHA synthase from Chromobacterium sp. USM2

謝銘輝

The 17th Annual meeting of the protein science society of Japan 2017年6月20日
A closed conformation of the catalytic domain of PHA synthase from Chromobacterium sp. USM2

謝銘輝

The 6th International Conference on Bio-based Polymers (ICBP 2017) 2017年5月14日

担当経験のある科目(授業)

2020年12月 - 2022年11月

Biotechnology/ Biochemistry/ Bioinformatics/ Protein crystallography (Adjunct Lecturer) (Faculty of Applied Sciences, UCSI University, Kuala Lumpur, Malaysia)

所属学協会

共同研究・競争的資金等の研究課題

Structural insights into the catalytic intermediate of PHA synthase, a bioplastic-producing enzyme

日本学術振興会科学研究費助成事業若手研究 2025年4月 - 2027年3月

謝銘輝
新規PET分解菌のシングルセルゲノム情報に基づくPET代謝の理解と応用

日本学術振興会科学研究費助成事業挑戦的研究(萌芽) 2024年6月 - 2026年3月

吉田昭介, 細川正人, 謝銘輝
Structure-guided engineering of a biodegradable plastic synthase for tailor-made polymer production

日本学術振興会科学研究費助成事業若手研究若手研究 2021年4月 - 2024年3月

謝銘輝

チェクミンフェイ

基本情報

研究キーワード

研究分野

経歴

学歴

受賞

論文

書籍等出版物

講演・口頭発表等

担当経験のある科目(授業)

所属学協会

共同研究・競争的資金等の研究課題

メニュー

共著者の一覧