Shigekazu Takahashi

Profile Information

Affiliation: Hiroshima University
: 主任研究員, 研究開発部, プラチナバイオ株式会社

Degree: 博士（学術）(東京大学)

Researcher number: 10600033
J-GLOBAL ID: 201501011512480711
researchmap Member ID: B000250337

Research Interests

Research Areas

Research History

Apr, 2023 - Present

Hiroshima University
Jul, 2022 - Present

主任研究員, 研究開発部, プラチナバイオ株式会社
Jul, 2022 - Mar, 2023

Hiroshima University
Sep, 2018 - Jun, 2022

Iwate Biotechnology Research Center
Apr, 2017 - Aug, 2018

主任主事, 産業創造課, 公益財団法人千葉市産業振興財団
Sep, 2015 - Mar, 2017

Faculty of Life Sciences, Toyo University
Sep, 2014 - Aug, 2015

National Agriculture and Food Research Organization
Apr, 2010 - Aug, 2014

Toho University

Awards

May, 2015

第6回日本光合成学会優秀ポスター賞, 日本光合成学会

高橋重一

Papers

De Novo Transcriptome Analysis Reveals Flowering-Related Genes That Potentially Contribute to Flowering-Time Control in the Japanese Cultivated Gentian Gentiana triflora.

Tomoyuki Takase, Motoki Shimizu, Shigekazu Takahashi, Keiichirou Nemoto, Fumina Goto, Chiharu Yoshida, Akira Abe, Masahiro Nishihara

International journal of molecular sciences, 23(19), Oct 4, 2022 Peer-reviewed
Isolation and functional analysis of EPHEMERAL1-LIKE (EPH1L) gene involved in flower senescence in Japanese cultivated gentian

Shigekazu Takahashi, Chiharu Yoshida, Hideyuki Takahashi, Masahiro Nishihara

International Journal of Molecular Sciences, 23(10) 5608, May, 2022 Peer-reviewedLead author
Identification of Candidate Genes Responsible for Flower Colour Intensity in Gentiana triflora.

Keisuke Tasaki, Aiko Watanabe, Keiichirou Nemoto, Shigekazu Takahashi, Fumina Goto, Nobuhiro Sasaki, Takashi Hikage, Masahiro Nishihara

Frontiers in plant science, 13 906879-906879, May, 2022 Peer-reviewed
Post-transcriptional gene silencing of the chalcone synthase gene CHS causes corolla lobe-specific whiting of Japanese gentian

Yuka Ohta, Go Atsumi, Chiharu Yoshida, Shigekazu Takahashi, Motoki Shimizu, Masahiro Nishihara, Takashi Nakatsuka

Planta, 255(1) 29-29, Jan, 2022 Peer-reviewed
Excitonic energy level of homo- and hetero-dimers and their composition in the Native Water-Soluble Chlorophyll Protein from Lepidium Virginicum

Takayuki Ohtsuki, Akira Uchida, Atsuko Nishigaki, Umpei Nagashima, Shigekazu Takahashi, Shigeru Ohshima

Bulletin of the Chemical Society of Japan, 94(2) 418-426, Feb, 2021 Peer-reviewed
A new finding that Japanese gentians perform photosynthesis at the green spots on the corolla

Takahashi S, Nishihara, M

光合成研究, 30(2) 157-165, Dec, 2020 Peer-reviewedLead authorCorresponding author
Morphological and cytological observations of corolla green spots reveal the presence of functional chloroplasts in Japanese gentian.

Shigekazu Takahashi, Suguru Ozawa, Kintake Sonoike, Katsutomo Sasaki, Masahiro Nishihara

PloS one, 15(8) e0237173, 2020 Peer-reviewedLead author
Varietal Differences in High Temperature-induced Flowering Retardation and Repression of Florigen Gene FTL3 in Summer-to-autumn-flowering Small-flowered Spray-type Chrysanthemums

Yoshio Mori, Yoshihiro Nakano, Yuki Hayashi, Shigekazu Takahashi, Tamotsu Hisamatsu, Katsuhiko Sumitomo

Horticultural Research (Japan), 18(4) 381-390, Dec, 2019 Peer-reviewed
Chrysanthemum requires short-day repeats for anthesis: Gradual CsFTL3 induction through a feedback loop under short-day conditions.

Yoshihiro Nakano, Tomoyuki Takase, Shigekazu Takahashi, Katsuhiko Sumitomo, Yohei Higuchi, Tamotsu Hisamatsu

Plant science : an international journal of experimental plant biology, 283 247-255, Jun, 2019 Peer-reviewed
Chlorophyll a/b binding-specificity in water-soluble chlorophyll protein.

Daniel M Palm, Alessandro Agostini, Vivien Averesch, Philipp Girr, Mara Werwie, Shigekazu Takahashi, Hiroyuki Satoh, Elmar Jaenicke, Harald Paulsen

Nature plants, 4(11) 920-929, Nov, 2018 Peer-reviewed
Subcellular localization of Arabidopsis thaliana heme-binding protein 1 (AtHBP1), AtHBP2 and AtHBP3

Kyoko Aizawa, Shigekazu Takahashi, Katsumi Nakayama, Hiroyuki Satoh

Journal of Plant Biochemistry and Biotechnology, 25(2) 215-218, Oct, 2016 Peer-reviewed
Molecular Cloning and Functional Expression of a Class IIA Water-Soluble Chlorophyll-Binding Protein from Brassica nigra

ONO Mayuko, TAKAHASHI Shigekazu, SHIBATA Risa, TOMIZAWA Mizuki, NAKAYAMA Katsumi, SATOH Hiroyuki

Research and Reviews: Journal of Botanical Science, 5(2) 33-35, May, 2016 Peer-reviewed
Structure of Water-soluble Chlorophyll-binding Protein from Chenopodium album

TAKAHASHI Shigekazu, OHTSUKI Takayuki, UCHIDA Akira, NAKAYAMA Katsumi, SATOH Hiroyuki

25(3) 181-185, Dec, 2015 Peer-reviewedLead author
Water-soluble chlorophyll-binding proteins from Arabidopsis thaliana and Raphanus sativus target the endoplasmic reticulum body

Shigekazu Takahashi, Kyoko Aizawa, Katsumi Nakayama, Hiroyuki Satoh

BMC Research Notes, 8(1) 365, Aug 20, 2015 Peer-reviewedLead author
Are tyrosine residues involved in the photoconversion of the water-soluble chlorophyll-binding protein of Chenopodium album?

Shigekazu Takahashi, Yumiko Seki, Akira Uchida, Katsumi Nakayama, Hiroyuki Satoh

Plant Biology (Stuttgart, Germany), 17(3) 632-638, May, 2015 Peer-reviewedLead author
Accumulation of alkaline earth metals by the green macroalga Bryopsis maxima.

Shigekazu Takahashi, Kyoko Aizawa, Saki Nakamura, Katsumi Nakayama, Shingo Fujisaki, Soichiro Watanabe, Hiroyuki Satoh

Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 28(2) 391-400, Apr, 2015 Peer-reviewedLead author
Assembly of water-soluble chlorophyll-binding proteins with native hydrophobic chlorophylls in water-in-oil emulsions.

Dominika Bednarczyk, Shigekazu Takahashi, Hiroyuki Satoh, Dror Noy

Biochimica et biophysica acta, 1847(3) 307-313, Mar, 2015 Peer-reviewed
Identification of genes encoding photoconvertible (Class I) water-soluble chlorophyll-binding proteins from Chenopodium ficifolium.

Shigekazu Takahashi, Eriko Abe, Katsumi Nakayama, Hiroyuki Satoh

Bioscience, biotechnology, and biochemistry, 79(2) 205-10, Feb, 2015 Peer-reviewedLead author
Effect of near-infrared irradiation on photoconversion of the water-soluble chlorophyll-binding protein of Chenopodium album.

Shigekazu Takahashi, Akira Uchida, Katsumi Nakayama, Hiroyuki Satoh

Bioscience, biotechnology, and biochemistry, 79(3) 439-42, Mar, 2015 Peer-reviewedLead author
Three-step photoconversion of only three subunits of the water-soluble chlorophyll-binding protein tetramer from Chenopodium album.

Shigekazu Takahashi, Akira Uchida, Katsumi Nakayama, Hiroyuki Satoh

The protein journal, 33(4) 337-43, Aug, 2014 Peer-reviewedLead author

Misc.

Development of SNP-molecular markers from RNA sequencing in Japanese cultivated gentian

高橋重一, 清水元樹, 高瀬智敬, 根本圭一郎, 阿部陽, 後藤史奈, 吉田千春, 平渕亜紀子, 小田島雅, 小澤傑 …

育種学研究, 24, 2022
RNA-seq analysis of bicolored gentian cultivar ‘Hakuju’

中塚貴司, 太田侑花, 厚見剛, 厚見剛, 吉田千春, 高橋重一, 清水元樹, 西原昌宏

園芸学研究別冊, 21(1), 2022
CRISPR/Cas9-mediated mutagenesis of EPHEMERAL1 homolog delays corolla senescence in Japanese gentian

高橋重一, 吉田千春, 高橋秀行, 西原昌宏

育種学研究, 24, 2022
Transcriptome profiling of the photoperiodic flowering induction in gentian

高瀬智敬, 高橋重一, 清水元樹, 根本圭一郎, 阿部陽, 西原昌宏

育種学研究, 23, 2021
Development of SNP markers associated with flowering time in gentian by RNA-Seq analysis

高橋重一, 高瀬智敬, 清水元樹, 根本圭一郎, 阿部陽, 後藤史奈, 吉田千春, 小田島雅, 西原昌宏

育種学研究, 23, 2021
Production of Transgene-Free Genome-Edited Plants (Null Segregants) in Japanese Cultivated Gentians

NISHIHARA Masahiro, WATANABE Aiko, GOTO Fumina, YOSHIDA Chiharu, TAKAHASHI Shigekazu, NEMOTO Keiichiro, ABE Akira, ODASHIMA Masashi, SASAKI Shinobu, OZAWA Suguru …

日本植物生理学会年会(Web), 62nd, 2021
Chrysanthemums require short-day repeats for flowering: involvement of FTL3 positive self-feedback regulation in phased induction

中野善公, 高瀬智敬, 高橋重一, 樋口洋平, 住友克彦, 久松完

園芸学研究別冊, 19(1), 2020
Characterization of green petal spots of Japanese gentian

高橋重一, 小澤傑, 園池公毅, 佐々木克友, 西原昌宏

園芸学研究別冊, 19(1), 2020
ゲノム編集技術のリンドウへの適用

西原昌宏, 渡辺藍子, 後藤史奈, 吉田千春, 根本圭一郎, 高橋重一, 佐々木伸大, 高橋秀行, 田崎啓介

日本植物細胞分子生物学会大会・シンポジウム講演要旨集, 37th, 2019
キクの開花に繰り返し短日遭遇を必要とさせるフロリゲン様遺伝子自己誘導機構

中野善公, 高瀬智敬, 住友克彦, 久松完, 高橋重一, 樋口洋平

農研機構野菜花き研究部門成果情報(Web), 2019, 2019
台風常襲地における耐候性LED電球を活用したキクの安定生産技術

住友克彦, 久松完, 中野善公, 小田篤, 高橋重一, 桐原弘, 和田健吾, 西原健作, 橋口満洋, 竹内秀樹 …

農研機構野菜花き研究部門成果情報(Web), 2017, 2017
Chl-binding ability and photoconvertibility of Chenopodium album water-soluble chlorophyll-binding protein mutants

TAKAHASHI Shigekazu, UCHIDA Akira, SATOH Hiroyuki

日本植物生理学会年会要旨集, 57th, 2016
クロロフィルbに高い親和性を示す水溶性クロロフィル結合タンパク質(WSCP)の探索と解析

富澤美月, 小野真由子, 高橋重一, 佐藤浩之

日本分子生物学会年会プログラム・要旨集(Web), 39th ROMBUNNO.1P‐0050 (WEB ONLY), 2016
キクタニギクの花成抑制に及ぼす暗期中の赤色もしくは遠赤色光の照射タイミングの影響

TAKAHASHI SHIGEKAZU, NAKANO YOSHIHIRO, SUMITOMO KATSUHIKO, HISAMATSU, TAMOTSU

園芸学研究別冊, 14(2) 272, Sep 26, 2015
シロザ由来の水溶性クロロフィル結合タンパク質の植物内における発現プロファイルおよび局在の解析

TAKAHASHI SHIGEKAZU, NAKAYAMA KATSUMI, SATO HIROYUKI

日本植物生理学会年会要旨集, 56th 264, Mar 9, 2015
ヌタウナギ乳酸脱水素酵素Bの耐熱化の試み

NISHIGUCHI KEIICHI, TAKAHASHI SHIGEKAZU, SATO HIROYUKI, UCHIDA AKIRA, KUBOTA SOICHIRO, NIWA KAZUKI, GOTO YUJI, SATO KEIICHI, IHARA HIROSHI, YOKOTA HIROMITSU …

生物試料分析, 38(1) 53, Jan 7, 2015
大腸菌で発現させたヌタウナギ乳酸脱水素酵素の耐熱性・耐圧性

NISHIGUCHI YOSHIKAZU, TAKAHASHI SHIGEKAZU, SATO HIROYUKI, UCHIDA AKIRA, KATO CHIAKI, GOROMARU(SHINKAI) MICHIKO, OKADA MITSUMASA

日本動物学会大会予稿集, 85th 160, Aug 7, 2014
非光変換型水溶性クロロフィル結合タンパク質(Class II WSCP)のクロロフィル結合およびクロロフィル識別の分子機構の解明

TAKAHASHI SHIGEKAZU, YANAI HARUNA, UCHIDA AKIRA, NAKAYAMA KATSUMI, SATO HIROYUKI

日本植物生理学会年会要旨集, 55th 250, Mar 11, 2014
オオハネモによる海洋元素の生物濃縮に関する研究

SATO HIROYUKI, TAKAHASHI SHIGEKAZU, NAKAMURA SAKI, NAKAYAMA KATSUMI

藻類, 62(1) 54, Mar 10, 2014
緑藻オオハネモ葉緑体ゲノム全塩基配列決定と遺伝子クラスター解析

TAKEUCHI EIJI, ISHIKAWA ATSUSHI, ITAGAKI TADASHI, TAKAHASHI SHIGEKAZU, NAKAYAMA KATSUMI, SATO HIROYUKI

藻類, 62(1) 57, Mar 10, 2014

Books and Other Publications

Brassicaceae: Characterization, Functional Genomics and Health Benefits (Agriculture Issues and Policies)

Minglin Lang

Nova Science Pub Inc, Oct 26, 2013 (ISBN: 1628088567)

Presentations

Molecular structures of water-soluble chlorophyll-binding proteins

TAKAHASHI Shigekazu, UCHIDA Akira, SATOH Hiroyuki

Twelfth International Workshop on Supramolecular Nanoscience of Chemically Programmed Pigments, Jun, 2016 Invited
Molecular properties and chlorophyll-binding mechanism of non-photoconvertible water-soluble chlorophyll-binding proteins

TAKAHASHI Shigekazu

International Conference on Tetrapyrrole Photoreceptors of Photosynthetic Organisms 2015, Oct 14, 2015 Invited
Mechanisms of chlorophyll-binding and chlorophyll-selection of non-photoconvertible water-soluble chlorophyll-binding proteins

高橋重一

International Conference on Tetrapyrrole Photoreceptors of Photosynthetic Organisms 2015, Oct, 2015 Invited

Teaching Experience

Research Projects

リンドウ花弁にみられる緑色斑点の機能解析と形成機構の解明に向けた基盤整備

科学研究費助成事業基盤研究(C), 基盤研究(C), 日本学術振興会, Apr, 2022 - Mar, 2025

高橋重一
Establishment of foreign-gene-free genome editing technology in Japanese gentian

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2019 - Mar, 2022

Takahashi Shigekazu
中性園芸作物リンドウの開花制御基板技術の開発

イノベーション創出強化研究推進事業, 国立研究開発法人農業・食品産業技術総合研究機構, Apr, 2020 - Mar, 2022
ゲノム編集技術を活用した農作物品種・育種素材の開発

平成31年度戦略的プロジェクト研究推進事業ゲノム編集技術を活用した農作物品種・育種素材の開発, 農林水産省, Apr, 2020 - Mar, 2021
非光変換型水溶性クロロフィル結合タンパク質のクロロフィル結合および識別機構の解明

平成28年度笹川科学研究助成, 公益財団法人日本科学協会, Apr, 2016 - Mar, 2017

高橋重一
放射性ストロンチウムの除染に向けた金属元素生体濃縮機構の解析

第22回(平成25年度)植物研究助成, 新技術開発財団
シロザ由来の光変換型水溶性クロロフィル結合タンパク質のクロロフィル結合および光変換の分子メカニズムの解明

平成25年度研究助成金, 濱口生化学振興財団

高橋重一

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