Chikao Morimoto

J-GLOBAL         Last updated: Aug 21, 2019 at 15:49
 
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Name
Chikao Morimoto
Research funding number
30119028

Research Areas

 
 

Academic & Professional Experience

 
Sep 2005
 - 
2011
Visiting Professor, Nevada Cancer Institute, Nevada State University
 
Oct 2001
 - 
Aug 2005
Research Professor, MD Anderson Cancer Center, University of Texas
 
Mar 1995
 - 
Sep 2001
Visiting Professor, Medical School, Harvard University
 
1988
 - 
1995
Associate Professor, Medical School, Harvard Univesity
 
1982
 - 
1988
Assistant Professor, Medical School, Harvard University
 
1980
 - 
1982
Instructor in Medicine, Medical School, Harvard University
 

Published Papers

 
Novel Antibody-Drug Conjugate with Anti-CD26 Humanized Monoclonal Antibody and Transcription Factor IIH(TFIIH) Inhibitor, Triptolide, Inhibits Tumor Growth via Impairing mRNA Synthesis.
Hayashi M, Madokoro H, Yamada K, Nishida H, Morimoto C, Sakamoto M, Yanagawa H, Yamada T.
Cancers (Basel).   11(8) E1138   Aug 2019   [Refereed]
Characterization of novel anti-IL-26 neutralizing monoclonal antibodies for the treatment of inflammatory diseases including psoriasis.
Hatano R, Itoh T, Otsuka H, Okamoto S, Komiya E, Iwata S, Aune TM, Dang NH, Kuwahara-Arai K, Ohnuma K, Morimoto C
MAbs.   1-15   Aug 2019   [Refereed]
CD26 expression is attenuated by TGF-β and SDF-1 autocrine signaling on stromal myofibroblasts in human breast cancers.
Mezawa Y, Daigo Y, Takano A, Miyagi Y, Yokose T, Yamashita T, Morimoto C, Hino O, Orimo A
Cancer Med   8(8) 3936-3948   May 2019   [Refereed]
Ikeda T, Kobayashi S, Morimoto C
Biochemistry and biophysics reports   17 10-16   Mar 2019   [Refereed]
Development of novel monoclonal antibodies with specific binding affinity for denatured human CD26 in formalin-fixed paraffin-embedded and decalcified specimens.
Hatano R, Yamada T, Madokoro H, Otsuka H, Komiya E, Itoh T, Narita Y, Iwata S, Yamazaki H, Matsuoka S, Dang NH, Ohnuma K, Morimoto C
PLoS One   14(6) e0218330   Jun 2019   [Refereed]
Anti-human CD9 antibody Fab fragment impairs the internalization of extracellular vesicles and the nuclear transfer of their cargo proteins
Santos MF, Rappa G, Karbanova J, Vanier C, Morimoto C, Corbeil D, Lorico A
J Cell Mol Med.   23(6) 4408-4421   2019   [Refereed]
Itoh T, Hatano R, Komiya E, Otsuka H, Narita Y, Aune TM, Dang NH, Matsuoka S, Naito H, Tominaga M, Takamori K, Morimoto C, Ohnuma K
The Journal of investigative dermatology   139(4) 878-889   2019   [Refereed]
Okamoto T, Yamazaki H, Hatano R, Yamada T, Kaneko Y, Xu CW, Dang NH, Ohnuma K, Morimoto C
Biochemical and biophysical research communications   504(2) 491-498   Oct 2018   [Refereed]
Ohnuma K, Hatano R, Dang NH, Morimoto C
Modern rheumatology   1-32   Oct 2018   [Refereed]
Nishida H, Hayashi M, Morimoto C, Sakamoto M, Yamada T
Blood cancer journal   8(11) 99   Oct 2018   [Refereed]
A novel role for CD26/dipeptidyl peptidase IV as a therapeutic target.
Ohnuma K, Hatano R, Komiya E, Otsuka H, Itoh T, Iwao N, Kaneko Y, Yamada T, Dang NH, Morimoto C
Frontiers in bioscience (Landmark edition)   23 1754-1779   Jun 2018   [Refereed]
Ikeda T, Kobayashi S, Morimoto C
Data in brief   17 1078-1081   Apr 2018   [Refereed]
Ikeda T, Kobayashi S, Morimoto C
Data in brief   15 948-969   Dec 2017   [Refereed]
Kim KM, Noh JH, Bodogai M, Martindale JL, Yang X, Indig FE, Basu SK, Ohnuma K, Morimoto C, Johnson PF, Biragyn A, Abdelmohsen K, Gorospe M
Genes & development   31(15) 1529-1534   Aug 2017   [Refereed]
Komiya E, Hatano R, Otsuka H, Itoh T, Yamazaki H, Yamada T, Dang NH, Tominaga M, Suga Y, Kimura U, Takamori K, Morimoto C, Ohnuma K
Journal of dermatological science   86(3) 212-221   Jun 2017   [Refereed]
Angevin E, Isambert N, Trillet-Lenoir V, You B, Alexandre J, Zalcman G, Vielh P, Farace F, Valleix F, Podoll T, Kuramochi Y, Miyashita I, Hosono O, Dang NH, Ohnuma K, Yamada T, Kaneko Y, Morimoto C
British journal of cancer   116(9) 1126-1134   Apr 2017   [Refereed]
Ikeda T, Fragiadaki M, Shi-Wen X, Ponticos M, Khan K, Denton C, Garcia P, Bou-Gharios G, Yamakawa A, Morimoto C, Abraham D
Biochemistry and biophysics reports   7 246-252   Sep 2016   [Refereed]
Ikeda T, Fragiadaki M, Shi-Wen X, Ponticos M, Khan K, Denton C, Garcia P, Bou-Gharios G, Yamakawa A, Morimoto C, Abraham D
Data in brief   8 1377-1380   Sep 2016   [Refereed]
Mizutani N, Abe M, Matsuoka S, Kajino K, Wakiya M, Ohtsuji N, Hatano R, Morimoto C, Hino O
BMC research notes   9 324   Jun 2016   [Refereed]
Nomura S, Iwata S, Hatano R, Komiya E, Dang NH, Iwao N, Ohnuma K, Morimoto C
Biochemical and biophysical research communications   474(1) 111-117   May 2016   [Refereed]
Hayashi M, Madokoro H, Yamada K, Nishida H, Morimoto C, Sakamoto M, Yamada T
Cancer cell international   16 35   2016   [Refereed]
Omata Y, Nakamura S, Koyama T, Yasui T, Hirose J, Izawa N, Matsumoto T, Imai Y, Seo S, Kurokawa M, Tsutsumi S, Kadono Y, Morimoto C, Aburatani H, Miyamoto T, Tanaka S
PloS one   11(6) e0157992   2016   [Refereed]
Ohnuma K, Hatano R, Itoh T, Iwao N, Dang NH, Morimoto C
Critical reviews in immunology   36(3) 239-267   2016   [Refereed]
Ohnuma K, Hatano R, Morimoto C
Nature immunology   16(8) 791-792   Aug 2015   [Refereed]
Otsuki N, Iwata S, Yamada T, Hosono O, Dang NH, Hatano R, Ohnuma K, Morimoto C
Modern rheumatology   25(4) 562-570   Jul 2015   [Refereed]
Katayose T, Iwata S, Oyaizu N, Hosono O, Yamada T, Dang NH, Hatano R, Tanaka H, Ohnuma K, Morimoto C
Biochemical and biophysical research communications   460(4) 1069-1075   May 2015   [Refereed]
Ohnuma K, Hatano R, Aune TM, Otsuka H, Iwata S, Dang NH, Yamada T, Morimoto C
Journal of immunology (Baltimore, Md. : 1950)   194(8) 3697-3712   Apr 2015   [Refereed]
Ohnuma K, Saito T, Hatano R, Hosono O, Iwata S, Dang NH, Ninomiya H, Morimoto C
Journal of clinical laboratory analysis   29(2) 106-111   Mar 2015   [Refereed]
Hatano R, Ohnuma K, Otsuka H, Komiya E, Taki I, Iwata S, Dang NH, Okumura K, Morimoto C
Journal of immunology (Baltimore, Md. : 1950)   194(3) 960-972   Feb 2015   [Refereed]
Nishida H, Suzuki H, Madokoro H, Hayashi M, Morimoto C, Sakamoto M, Yamada T
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research   29(11) 2439-2455   Nov 2014   [Refereed]
Komiya E, Ohnuma K, Yamazaki H, Hatano R, Iwata S, Okamoto T, Dang NH, Yamada T, Morimoto C
Biochemical and biophysical research communications   447(4) 609-615   May 2014   [Refereed]
Yamamoto J, Ohnuma K, Hatano R, Okamoto T, Komiya E, Yamazaki H, Iwata S, Dang NH, Aoe K, Kishimoto T, Yamada T, Morimoto C
British journal of cancer   110(9) 2232-2245   Apr 2014   [Refereed]
Kwan JC, Liu Y, Ratnayake R, Hatano R, Kuribara A, Morimoto C, Ohnuma K, Paul VJ, Ye T, Luesch H
Chembiochem : a European journal of chemical biology   15(6) 799-804   Apr 2014   [Refereed]
Hatano R, Yamada T, Matsuoka S, Iwata S, Yamazaki H, Komiya E, Okamoto T, Dang NH, Ohnuma K, Morimoto C
Diagnostic pathology   9 30   Feb 2014   [Refereed]
Okamoto T, Iwata S, Yamazaki H, Hatano R, Komiya E, Dang NH, Ohnuma K, Morimoto C
PloS one   9(1) e86671   2014   [Refereed]
Fujimoto N, Ohnuma K, Aoe K, Hosono O, Yamada T, Kishimoto T, Morimoto C
PloS one   9(12) e115647   2014   [Refereed]
Ohnuma K, Haagmans BL, Hatano R, Raj VS, Mou H, Iwata S, Dang NH, Bosch BJ, Morimoto C
Journal of virology   87(24) 13892-13899   Dec 2013   [Refereed]
Havre PA, Dang LH, Ohnuma K, Iwata S, Morimoto C, Dang NH
BMC cancer   13 517   Nov 2013   [Refereed]
Saito T, Ohnuma K, Suzuki H, Dang NH, Hatano R, Ninomiya H, Morimoto C
Diabetes research and clinical practice   102(1) e8-e12   Oct 2013   [Refereed]
Tao X, Hill TE, Morimoto C, Peters CJ, Ksiazek TG, Tseng CT
Journal of virology   87(17) 9953-9958   Sep 2013   [Refereed]
Hatano R, Ohnuma K, Yamamoto J, Dang NH, Yamada T, Morimoto C
British journal of haematology   162(2) 263-277   Jul 2013   [Refereed]
Ikeda T, Kurosawa M, Morimoto C, Kitayama S, Nukina N
Biochemical and biophysical research communications   436(2) 121-127   Jun 2013   [Refereed]
Hatano R, Ohnuma K, Yamamoto J, Dang NH, Morimoto C
Immunology   138(2) 165-172   Feb 2013   [Refereed]
Amatya VJ, Takeshima Y, Aoe K, Fujimoto N, Okamoto T, Yamada T, Kishimoto T, Morimoto C, Inai K
Oncology reports   29(1) 21-28   Jan 2013   [Refereed]
Yamada K, Hayashi M, Madokoro H, Nishida H, Du W, Ohnuma K, Sakamoto M, Morimoto C, Yamada T
PloS one   8(4) e62304   2013   [Refereed]

Misc

 
[Development of New Therapy for Malignant Mesothelioma Based on CD26 Molecule].
Morimoto C, Ohnuma K
Gan to kagaku ryoho. Cancer & chemotherapy   43(7) 855-862   Jul 2016   [Refereed]
[Antibody therapy for malignant mesothelioma: humanized anti-cD26 mAb therapy].
Morimoto C, Ohnuma K
Nihon rinsho. Japanese journal of clinical medicine   70(12) 2177-2182   Dec 2012   [Refereed]
[CD26 and its signaling pathway].
Ohnuma K, Morimoto C
Nihon rinsho. Japanese journal of clinical medicine   70 Suppl 8 176-180   Nov 2012   [Refereed]

Books etc

 
Advances in Medicine and Biology
Hatano R, Ohnuma K, Yamada T, Okamoto T, Komiya E, Otsuka H, Itoh T, Yamazaki H, Iwao N, Kaneko Y, Dang NH, Morimoto C. (Part:Contributor, The use of the humanized anti-CD26 monoclonal antibody YS110 as a novel targeted therapy for refractory cancers and immune disorders.)
Nova Science Publishers, Inc   2018   
Horizons in Cancer Research
Ohnuma K, Hatano R, Yamazaki H, Kaneko Y, Dang NH, Morimoto C. (Part:Contributor, CD26-targeted therapy: A new horizon in malignant pleural mesothelioma management)
Nova Science Publishers, Inc   2017