松元幸一郎 (KOICHIRO MATSUMOTO) - マイポータル

基本情報

所属: 福岡ハートネット病院総合内科　呼吸器内科医長
: 福岡歯科大学医科歯科総合病院内科呼吸器内科非常勤医師

研究者番号: 60325462
J-GLOBAL ID: 202101020565811520
researchmap会員ID: R000029752

主要な研究キーワード

もっとみる

研究分野

経歴

2025年9月 - 現在

福岡看護大学, 非常勤講師
2025年4月 - 現在

福岡歯科大学, 医科歯科総合病院内科, 呼吸器内科非常勤医師
2025年4月 - 現在

福岡ハートネット病院, 総合内科呼吸器内科, 医長
2022年4月 - 2025年3月

福岡歯科大学, 総合医学講座呼吸器内科学, 教授
2015年7月 - 2022年3月

九州大学大学院医学研究院, 呼吸器内科学分野, 准教授
2008年2月 - 2015年6月

九州大学病院, 呼吸器科, 講師
2003年10月 - 2008年1月

九州大学病院, 呼吸器科, 助教
2000年7月 - 2003年9月

九州大学医学部附属病院, 呼吸器科, 助手
1998年8月 - 2000年6月

マクマスター大学, 呼吸器部門, 博士号取得後研究員
1996年6月 - 1998年7月

九州大学医学部附属病院, 呼吸器科, 医員
1995年6月 - 1996年5月

医療法人長愛会菊地病院, 内科, 医員
1992年6月 - 1995年5月

九州大学医学部附属病院, 呼吸器科, 医員
1991年6月 - 1992年5月

北九州市立療養所松寿園, 内科技術吏員（医師）
1990年6月 - 1991年5月

九州厚生年金病院, 内科, 臨床研修医
1989年6月 - 1990年5月

九州大学医学部附属病院, 臨床研修医

学歴

1983年4月 - 1989年3月

九州大学, 医学部, 医学科

主要な委員歴

2018年4月 - 現在

日本呼吸器学会, 「COPD（慢性閉塞性肺疾患）診断と治療のためのガイドライン」作成委員
2015年5月 - 現在

日本アレルギー学会, 「喘息予防・管理ガイドライン」作成委員

もっとみる

受賞

2008年11月

アレルギー学術奨励賞, アボットジャパン
2005年9月

American College of Chest Physicians（ACCP）日本部会賞, American College of Chest Physicians（ACCP）日本部会
2002年10月

九州支部学術奨励賞, 日本呼吸器学会

主要な論文

204

Claudin-3 deficiency inhibits allergic responses in an ovalbumin-induced asthma mouse model

Yumiko Ishii, Ayaka Shiota, Tomoaki Takao, Norio Yamamoto, Tomohiro Ogawa, Akihiro Jo, Seiji Shinozaki, Satoru Fukuyama, Tomoaki Koga, Minako Ito …

Allergology International 2025年1月
Postnatal Allergic Inhalation Induces Glial Inflammation in the Olfactory Bulb and Leads to Autism-Like Traits in Mice.

Eizo Tanaka, Ryo Yamasaki, Ban-Yu Saitoh, Amina Abdelhadi, Satoshi Nagata, Sato Yoshidomi, Yuka Inoue, Koichiro Matsumoto, Jun-Ichi Kira, Noriko Isobe

International journal of molecular sciences 25(19) 2024年9月28日
Effects of treatment with corticosteroids on human rhinovirus-induced asthma exacerbations in pediatric inpatients: a prospective observational study.

Keiko Kan-O, Yasuyoshi Washio, Takeshi Oki, Tsuguto Fujimoto, Takahito Ninomiya, Makoto Yoshida, Masaki Fujita, Yoichi Nakanishi, Koichiro Matsumoto

BMC pulmonary medicine 23(1) 487-487 2023年12月5日査読有り最終著者
Computational fluid-particle dynamics modeling of ultrafine to coarse particles deposition in the human respiratory system, down to the terminal bronchiole

Nguyen Dang Khoa, Sixiao Li, Nguyen Lu Phuong, Kazuki Kuga, Hidetake Yabuuchi, Keiko Kan-o, Koichiro Matsumoto, Kazuhide Ito

Computer Methods and Programs in Biomedicine 107589-107589 2023年5月査読有り
Risks of dementia in a general Japanese older population with preserved ratio impaired spirometry: The Hisayama Study

Kenji Kawatoko, Yasuyoshi Washio, Tomoyuki Ohara, Satoru Fukuyama, Takanori Honda, Jun Hata, Taro Nakazawa, Keiko Kan-o, Hiromasa Inoue, Koichiro Matsumoto …

Journal of Epidemiology 2023年査読有り
Risks of Mortality and Airflow Limitation in Japanese with Preserved Ratio Impaired Spirometry.

Yasuyoshi Washio, Satoko Sakata, Satoru Fukuyama, Takanori Honda, Keiko Kan-O, Mao Shibata, Jun Hata, Hiromasa Inoue, Takanari Kitazono, Koichiro Matsumoto …

American journal of respiratory and critical care medicine 2022年5月12日査読有り
Incense smoke-induced oxidative stress disrupts tight junctions and bronchial epithelial barrier integrity and induces airway hyperresponsiveness in mouse lungs

Norio Yamamoto, Keiko Kan-o, Miyoko Tatsuta, Yumiko Ishii, Tomohiro Ogawa, Seiji Shinozaki, Satoru Fukuyama, Yoichi Nakanishi, Koichiro Matsumoto

Scientific Reports 11(1) 2021年12月査読有り最終著者
Inhibition of PI3Kδ Differentially Regulates Poly I:C– and Human Metapneumovirus–Induced PD–L1 and PD–L2 Expression in Human Bronchial Epithelial Cells

Tomohiro Ogawa, Keiko Kan-o, Ayaka Shiota, Akitaka Fujita, Yumiko Ishii, Satoru Fukuyama, Koichiro Matsumoto

Frontiers in Immunology 12 2021年11月25日査読有り最終著者
Early postnatal allergic airway inflammation induces dystrophic microglia leading to excitatory postsynaptic surplus and autism-like behavior

Ban yu Saitoh, Eizo Tanaka, Norio Yamamoto, Daan van Kruining, Kyoko Iinuma, Yuko Nakamuta, Hiroo Yamaguchi, Ryo Yamasaki, Koichiro Matsumoto, Jun ichi Kira

Brain, Behavior, and Immunity 95 362-380 2021年7月査読有り
Airflow limitation and tongue microbiota in community-dwelling elderly individuals.

Toru Takeshita, Koichiro Matsumoto, Michiko Furuta, Satoru Fukuyama, Kenji Takeuchi, Hiroaki Ogata, Mikari Asakawa, Shinya Kageyama, Jun Hata, Toshiharu Ninomiya …

ERJ open research 7(2) 2021年4月査読有り
Differences in the spectrum of respiratory viruses and detection of human rhinovirus C in exacerbations of adult asthma and chronic obstructive pulmonary disease

Keiko Kan-o, Yasuyoshi Washio, Tsuguto Fujimoto, Natsuko Shiroyama, Takako Nakano, Kentaro Wakamatsu, Shohei Takata, Makoto Yoshida, Masaki Fujita, Koichiro Matsumoto

Respiratory Investigation 2021年査読有り最終著者
Inhibition of PI3Kδ Enhances Poly I:C-Induced Antiviral Responses and Inhibits Replication of Human Metapneumovirus in Murine Lungs and Human Bronchial Epithelial Cells

Akitaka Fujita, Keiko Kan-o, Ken Tonai, Norio Yamamoto, Tomohiro Ogawa, Satoru Fukuyama, Yoichi Nakanishi, Koichiro Matsumoto

Frontiers in Immunology 11 2020年3月11日査読有り最終著者
Pleuropulmonary paragonimiasis with multiple nodules in the pleura

Hiroaki Ogata, Eiji Harada, Soichiro Moriya, Satoru Fukuyama, Kunihiro Suzuki, Yoshimasa Shiraishi, Hiroyuki Ando, Kazuyasu Uryu, Seiji Shinozaki, Maako Ide …

Internal Medicine 59(15) 1879-1881 2020年
Effects of cigarette smoke on barrier function and tight junction proteins in the bronchial epithelium: Protective role of cathelicidin LL-37

Miyoko Tatsuta, Keiko Kan-O, Yumiko Ishii, Norio Yamamoto, Tomohiro Ogawa, Satoru Fukuyama, Aimi Ogawa, Akitaka Fujita, Yoichi Nakanishi, Koichiro Matsumoto

Respiratory Research 20(1) 2019年11月9日査読有り最終著者
Periodontitis Is Associated with Chronic Obstructive Pulmonary Disease

K. Takeuchi, K. Matsumoto, M. Furuta, S. Fukuyama, T. Takeshita, H. Ogata, S. Suma, Y. Shibata, Y. Shimazaki, J. Hata …

Journal of Dental Research 98(5) 534-540 2019年5月1日査読有り
Trends in the prevalence of airflow limitation in a general Japanese population: two serial cross-sectional surveys from the Hisayama Study.

Hiroaki Ogata, Yoichiro Hirakawa, Koichiro Matsumoto, Jun Hata, Daigo Yoshida, Satoru Fukuyama, Hiromasa Inoue, Takanari Kitazono, Toshiharu Ninomiya, Yoichi Nakanishi

BMJ open 9(3) e023673 2019年3月20日査読有り
Periodontal status and lung function decline in the community: the Hisayama study

Kenji Takeuchi, Koichiro Matsumoto, Michiko Furuta, Satoru Fukuyama, Toru Takeshita, Hiroaki Ogata, Shino Suma, Yukie Shibata, Yoshihiro Shimazaki, Jun Hata …

Scientific Reports 8(1) 2018年12月1日
Effects of corticosteroid plus long-acting beta<inf>2</inf>-agonist on the expression of PD-L1 in double-stranded RNA-induced lung inflammation in mice

Saaka Hamano, Koichiro Matsumoto, Ken Tonai, Satoru Fukuyama, Keiko Kan-O, Nanae Seki, Hiromasa Inoue, Yoichi Nakanishi

Journal of Inflammation (United Kingdom) 14(1) 2017年1月17日
Association of airflow limitation with carotid atherosclerosis in a japanese community ― the hisayama study

Kunihiro Kudo, Jun Hata, Koichiro Matsumoto, Yuki Shundo, Satoru Fukuyama, Hiromasa Inoue, Takanari Kitazono, Yutaka Kiyohara, Toshiharu Ninomiya, Yoichi Nakanishi

Circulation Journal 81(12) 1846-1853 2017年
Comparison of the COPD population screener and international primary care airway group questionnaires in a general japanese population: The hisayama study

Go Tsukuya, Takuya Samukawa, Koichiro Matsumoto, Satoru Fukuyama, Tomohiro Kumamoto, Akifumi Uchida, Chihaya Koriyama, Toshiharu Ninomiya, Hiromasa Inoue

International Journal of COPD 11(1) 1903-1909 2016年8月16日
Prevalence of asthma with airflow limitation, COPD, and COPD with variable airflow limitation in older subjects in a general Japanese population: The Hisayama Study

Koichiro Matsumoto, Nanae Seki, Satoru Fukuyama, Atsushi Moriwaki, Keiko Kan-o, Yuko Matsunaga, Naotaka Noda, Makoto Yoshida, Hiroshi Koto, Shohei Takata …

Respiratory Investigation 53(1) 22-29 2015年1月1日
Viral infections in asthma and COPD.

Koichiro Matsumoto, Hiromasa Inoue

Respiratory investigation 52(2) 92-100 2014年3月
Cigarette smoke impairs phagocytosis of apoptotic neutrophils by alveolar macrophages via inhibition of the histone deacetylase/Rac/CD9 pathways

Naotaka Noda, Koichiro Matsumoto, Satoru Fukuyama, Yukari Asai, Hiroko Kitajima, Nanae Seki, Yuko Matsunaga, Keiko Kan-O, Atsushi Moriwaki, Konosuke Morimoto …

International Immunology 25(11) 643-650 2013年11月
PI3K-delta mediates double-stranded RNA-induced upregulation of B7-H1 in BEAS-2B airway epithelial cells

Keiko Kan-o, Koichiro Matsumoto, Yukari Asai-Tajiri, Satoru Fukuyama, Saaka Hamano, Nanae Seki, Yoichi Nakanishi, Hiromasa Inoue

Biochemical and Biophysical Research Communications 435(2) 195-201 2013年5月31日
Corticosteroids plus long-acting Beta<inf>2</inf>-agonists prevent double-stranded RNA-induced upregulation of B7-H1 on airway epithelium

K. Kan-O, K. Matsumoto, H. Inoue, S. Fukuyama, Y. Asai, W. Watanabe, M. Kurokawa, J. Araya, K. Kuwano, Y. Nakanishi

International Archives of Allergy and Immunology 160(1) 27-36 2012年12月
IL-6 induced by double-stranded RNA augments allergic inflammation via suppression of Foxp3⁺T-cell/IL-10 axis

Koichiro Matsumoto, Yukari Asai, Satoru Fukuyama, Keiko Kan-o, Yuko Matsunaga, Naotaka Noda, Hiroko Kitajima, Kentaro Tanaka, Yoichi Nakanishi, Hiromasa Inoue

American Journal of Respiratory Cell and Molecular Biology 46(6) 740-747 2012年6月
Essential role of B7-H1 in double-stranded RNA-induced augmentation of an asthma phenotype in mice

Koichiro Matsumoto, Keiko Kan-o, Miyuki Eguchi-Tsuda, Satoru Fukuyama, Yukari Asai, Takafumi Matsumoto, Atsushi Moriwaki, Yuko Matsunaga, Hiroko Tsutsui, Taro Kawai …

American Journal of Respiratory Cell and Molecular Biology 45(1) 31-39 2011年7月1日
The transcription factor E4BP4 regulates the production of IL-10 and IL-13 in CD4⁺ T cells

Yasutaka Motomura, Hiroshi Kitamura, Atsushi Hijikata, Yuko Matsunaga, Koichiro Matsumoto, Hiromasa Inoue, Koji Atarashi, Shohei Hori, Hiroshi Watarai, Jinfang Zhu …

Nature Immunology 12(5) 450-459 2011年5月
T cell treatment with small interfering RNA for suppressor of cytokine signaling 3 modulates allergic airway responses in a murine model of asthma

Atsushi Moriwaki, Hiromasa Inoue, Takako Nakano, Yuko Matsunaga, Yukiko Matsuno, Takafumi Matsumoto, Satoru Fukuyama, Keiko Kan-o, Koichiro Matsumoto, Miyuki Tsuda-Eguchi …

American Journal of Respiratory Cell and Molecular Biology 44(4) 448-455 2011年4月
IL-13 suppresses double-stranded RNA-induced IFN-λ production in lung cells

Atsushi Moriwaki, Koichiro Matsumoto, Yuko Matsunaga, Satoru Fukuyama, Takafumi Matsumoto, Keiko Kan-o, Naotaka Noda, Yukari Asai, Yoichi Nakanishi, Hiromasa Inoue

Biochemical and Biophysical Research Communications 404(4) 922-927 2011年1月28日
Pulmonary suppressor of cytokine signaling-1 induced by IL-13 regulates allergic asthma phenotype

Satoru Fukuyama, Takako Nakano, Takafumi Matsumoto, Brian G.G. Oliver, Janette K. Burgess, Atsushi Moriwaki, Kentaro Tanaka, Masato Kubo, Tomoaki Hoshino, Hiroyuki Tanaka …

American Journal of Respiratory and Critical Care Medicine 179(11) 992-998 2009年6月1日
B7-DC induced by IL-13 works as a feedback regulator in the effector phase of allergic asthma

Koichiro Matsumoto, Satoru Fukuyama, Miyuki Eguchi-Tsuda, Takako Nakano, Takafumi Matsumoto, Mikiko Matsumura, Atsushi Moriwaki, Keiko Kan-o, Yoshihiro Wada, Hideo Yagita …

Biochemical and Biophysical Research Communications 365(1) 170-175 2008年1月4日
Overexpression of B7-H1 (PD-L1) significantly associates with tumor grade and postoperative prognosis in human urothelial cancers

Juro Nakanishi, Yoshihiro Wada, Koichiro Matsumoto, Miyuki Azuma, Ken Kikuchi, Shoichi Ueda

Cancer Immunology, Immunotherapy 56(8) 1173-1182 2007年8月
Niflumic acid suppresses interleukin-13-induced asthma phenotypes

Takako Nakano, Hiromasa Inoue, Satoru Fukuyama, Koichiro Matsumoto, Mikiko Matsumura, Miyuki Tsuda, Takafumi Matsumoto, Hisamichi Aizawa, Yoichi Nakanishi

American Journal of Respiratory and Critical Care Medicine 173(11) 1216-1221 2006年6月1日
Exacerbation of experimental allergic asthma by augmented Th2 responses in WSX-1-deficient mice

Yoshiyuki Miyazaki, Hiromasa Inoue, Mikiko Matsumura, Koichiro Matsumoto, Takako Nakano, Miyuki Tsuda, Shinjiro Hamano, Akihiko Yoshimura, Hiroki Yoshida

Journal of Immunology 175(4) 2401-2407 2005年8月15日
Expression of B7-H1 and B7-DC on the airway epithelium is enhanced by double-stranded RNA

Miyuki Tsuda, Koichiro Matsumoto, Hiromasa Inoue, Mikiko Matsumura, Takako Nakano, Akio Mori, Miyuki Azuma, Yoichi Nakanishi

Biochemical and Biophysical Research Communications 330(1) 263-270 2005年4月
B7-DC Regulates Asthmatic Response by an IFN-γ-Dependent Mechanism

Koichiro Matsumoto, Hiromasa Inoue, Takako Nakano, Miyuki Tsuda, Yuki Yoshiura, Satoru Fukuyama, Fumihiko Tsushima, Tomoaki Hoshino, Hisamichi Aizawa, Hisaya Akiba …

Journal of Immunology 172(4) 2530-2541 2004年2月15日
Decrease of interleukin-10-producing T cells in the peripheral blood of severe unstable atopic asthmatics

Koichiro Matsumoto, Hiromasa Inoue, Satoru Fukuyama, Miyuki Tsuda, Tomomi Ikegami, Atsuko Kibe, Yuki Yoshiura, Masashi Komori, Naotaka Hamasaki, Hisamichi Aizawa …

International Archives of Allergy and Immunology 134(4) 295-302 2004年
SOCS-3 regulates onset and maintenance of T<inf>H</inf>2-mediated allergic responses

Yoh Ichi Seki, Hiromasa Inoue, Naoko Nagata, Katsuhiko Hayashi, Satoru Fukuyama, Koichiro Matsumoto, Okiru Komine, Shinjiro Hamano, Kunisuke Himeno, Kyoko Inagaki-Ohara …

Nature Medicine 9(8) 1047-1054 2003年8月1日
Differential regulation by glucocorticoid of interleukin-13-induced eosinophilia, hyperresponsiveness, and goblet cell hyperplasia in mouse airways

Atsuko Kibe, Hiromasa Inoue, Satoru Fukuyama, Kentaro Machida, Koichiro Matsumoto, Hiroshi Koto, Tomomi Ikegami, Hisamichi Aizawa, Nobuyuki Hara

American Journal of Respiratory and Critical Care Medicine 167(1) 50-56 2003年1月1日
Pathogenesis of murine experimental allergic rhinitis: A study of local and systemic consequences of IL-5 deficiency

Hiroko Saito, Koichiro Matsumoto, Avram E. Denburg, Lynn Crawford, Russ Ellis, Mark D. Inman, Roma Sehmi, Kiyoshi Takatsu, Klaus I. Matthaei, Judah A. Denburg

Journal of Immunology 168(6) 3017-3023 2002年3月15日
Il-10 production in circulating T cells differs between allergen-induced isolated early and dual asthmatic responders

Koichiro Matsumoto, Gail M. Gauvreau, Tracy Rerecich, Richard M. Watson, Lorna J. Wood, Paul M. O'Byrne

Journal of Allergy and Clinical Immunology 109(2) 281-286 2002年
Th type 1-stimulating activity of lung macrophages inhibits Th2-mediated allergic airway inflammation by an IFN-γ-dependent mechanism

C. Tang, M. D. Inman, N. Van Rooijen, P. Yang, H. Shen, K. Matsumoto, P. M. O'Byrne

Journal of Immunology 166(3) 1471-1481 2001年2月1日
Role of neutrophil elastase in ozone-induced airway responses in guinea- pigs

K. Matsumoto, H. Aizawa, H. Inoue, H. Koto, H. Nakano, N. Hara

European Respiratory Journal 14(5) 1088-1094 1999年
Eosinophilic airway inflammation induced by repeated exposure to cigarette smoke

K. Matsumoto, H. Aizawa, H. Inoue, H. Koto, S. Takata, M. Shigyo, H. Nakano, N. Hara

European Respiratory Journal 12(2) 387-394 1998年8月
Nitric oxide derived from sympathetic nerves regulates airway responsiveness to histamine in guinea pigs

Koichiro Matsumoto, Hisamichi Aizawa, Shohei Takata, Hiromasa Inoue, Naotsugu Takahashi, Nobuyuki Kara

Journal of Applied Physiology 83(5) 1432-1437 1997年11月
Thromboxane causes airway hyperresponsiveness after cigarette smoke-induced neurogenic inflammation

Koichiro Matsumoto, Hisamichi Aizawa, Hiromasa Inoue, Mutsumi Shigyo, Shohei Takata, Nobuyuki Hara

Journal of Applied Physiology 81(6) 2358-2364 1996年12月
Role of thromboxane-A<inf>2</inf> and cholinergic mechanisms in bronchoconstriction induced by cigarette smoke in guinea-pigs

K. Matsumoto, H. Aizawa, H. Inoue, S. Takata, M. Shigyo, N. Hara

European Respiratory Journal 9(12) 2468-2473 1996年
Effects of epithelial cell supernatant on membrane potential and contraction of dog airway smooth muscles.

K. Matsumoto, H. Aizawa, R. Inoue, S. Hamano, S. Ikeda, Z. Xie, M. Hirata, N. Hara, Y. Ito

American journal of respiratory cell and molecular biology 10(3) 322-330 1994年3月