論文

査読有り
2020年6月24日

Guided Internet-Based Cognitive Behavioral Therapy in Japanese Patients With Obsessive-Compulsive Disorder: Protocol for a Randomized Controlled Trial

JMIR Research Protocols
  • Kazuki Matsumoto
  • ,
  • Sayo Hamatani
  • ,
  • Takuya Makino
  • ,
  • Taku Uemura
  • ,
  • Futoshi Suzuki
  • ,
  • Seina Shinno
  • ,
  • Tomoki Ikai
  • ,
  • Hiroyuki Hayashi
  • ,
  • Chihiro Sutoh
  • ,
  • Eiji Shimizu

9
6
開始ページ
e18216
終了ページ
e18216
記述言語
掲載種別
研究論文(学術雑誌)
DOI
10.2196/18216
出版者・発行元
JMIR Publications Inc.

<sec>
<title>Background</title>
Cognitive behavioral therapy for obsessive-compulsive disorder has been established, but access to this therapy in Japan is limited. Internet-based cognitive behavioral therapy may improve treatment accessibility and sufficiently improve obsessive-compulsive symptoms. There are few randomized controlled trials examining the effectiveness of internet-based cognitive behavioral therapy in patients with obsessive-compulsive disorder. We designed a randomized controlled trial protocol to assess the effectiveness of guided internet-based cognitive behavioral therapy in Japanese patients with obsessive-compulsive disorder.


</sec>
<sec>
<title>Objective</title>
We aimed to develop a protocol for a randomized controlled trial of internet-based cognitive behavioral therapy in Japanese patients with obsessive-compulsive disorder.


</sec>
<sec>
<title>Methods</title>
The randomized controlled trial will compare internet-based cognitive behavioral therapy treatment and usual care groups, each consisting of 15 participants (n=30) diagnosed with obsessive-compulsive disorder. We will evaluate the effectiveness of a 12-week intervention. The primary outcome of symptom severity will be measured using the Yale-Brown Obsessive-Compulsive Scale. Secondary outcomes will be assessed with the Obsessive-Compulsive Inventory, Beck Anxiety Inventory, Patient Health Questionnaire-9, Generalized Anxiety Disorder-7, Working Alliance Inventory-Short Form, and the Euro Qol – 5 Dimension. All measures will be assessed at weeks 0 (baseline) and 12 (follow-up). In the statistical analysis comparing treatment effects, the least-squares means and their 95% CIs will be estimated by analysis of covariance with the change in total outcomes scores at week 12. All comparisons are planned, and all P values will be two-sided, with values &lt;.05 considered statistically significant.


</sec>
<sec>
<title>Results</title>
The study will be performed from January 2020 to March 2021, and results are expected to be available in mid-2021.


</sec>
<sec>
<title>Conclusions</title>
The trial will demonstrate whether internet-based cognitive behavioral therapy improves access and is more effective than more usual care for patients with obsessive-compulsive disorder in Japan.


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<title>Trial Registration</title>
University Hospital Medical Information Network (UMIN) 000039375; https://upload.umin.ac.jp/cgi-open-bin/ctr/ctr_view.cgi?recptno=R000044422


</sec>
<sec>
<title>International Registered Report Identifier (IRRID)</title>
DERR1-10.2196/18216


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リンク情報
DOI
https://doi.org/10.2196/18216
ID情報
  • DOI : 10.2196/18216
  • eISSN : 1929-0748

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