Yoko Toyoshima

J-GLOBAL         Last updated: Jan 5, 2019 at 01:31
 
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Name
Yoko Toyoshima
E-mail
cyytoyomail.ecc.u-tokyo.ac.jp
Affiliation
The University of Tokyo
Research funding number
40158043

Research Interests

 
 

Research Areas

 
 

Academic & Professional Experience

 
2006
 - 
2018
Professor, Dpartment of Life Sciences, Graduate School of Arts and Sciences, The University of Tokyo
 

Published Papers

 
Axonemal Dynein Light Chain-1 Locates at the Microtubule Binding Domain of the γ Heavy Chain
Ichikawa M., Saito K., Yanagisawa H., Yagi, T., Kamiya, R., Yamaguchi S., Yajima, J., Kushida Y., Nakano, K., Numata, O. and Toyoshima, Y. Y.
MBoC   26 4236-4247   2016   [Refereed]
Circular orientation fluorescence emitter imaging (COFEI) of rotational motion of motor proteins
Mitsuhiro Sugawa, Tomoko Masaike, Nagisa Mikami,Shin Yamaguchi, Keitaro Shibata, Kei Saito, Fumihiko Fujii, Yoko Y. Toyoshima, Takayuki Nishizaka, Junichiro Yajima
Biochem Biophys Res Commun.   504(4) 709-714   2018   [Refereed]
Dynactin has two antagonistic regulatory domains and exerts opposing effects on dynein motility.
Kobayashi T., Miyashita, T., Murayama, T. and Toyoshima, Y. Y.
PLOS One   12(8) e0183672   2017   [Refereed]
α- and β-tubulin lattice arrangement of the axonemal microtubule doublet and binding proteins revealed by single particle cryo-electron microscopy and tomography. Structure 23, 1584-1595.
Maheshwari, A., Obbineni, J. M., Bui, K. H., Shibata, K., Toyoshima Y. Y. & Ishikawa, T.
Structure   23 1584-1595   2015   [Refereed]
Formation of ring-shaped microtubule assemblies through active self-organization on dynein.
Ito, M., Arif Md. Rashedul Kabir, A.,M.,R. Inoue, D., Torisawa, T, Toyoshima, Y.Y., Sada1, K. & Kakugo, A.
Polymer J.   46(220) 225   2014   [Refereed]
Sea lily muscle lacks a troponin-regulatory system, while it contains paramyosin.
Obinata, T., Amemiya, S., Takai, R., Ichikawa, M., Toyoshima, Y.Y. & Sato, N.
Zool. Sci.   31 122-128   2014   [Refereed]
Structure of the entire stalk region of the dynein motor domein.
Nishikawa, Y., Oyama, T., Kamiya, N., Kon, T., Toyoshima, Y. Y., Nakamura, H. & Kuris, G.
J. Mol. Biol.   426 3232-3245   2014   [Refereed]
Autoinhibition and cooperative activation mechanisms of cytoplasmic dynein.
Torisawa, T., Ichikawa, M., Furuta, A., Saito, K., Oiwa, K., Kojima, H., Toyoshima, Y. Y. & Furuta, K.
Nature Cell Biol.   16(11) 1118-1124   2014   [Refereed]
Torque generation by axonemal outer-arm dynein
Yamaguchi, S., Saito, K., Sutoh, M., Nishizaka, T., Toyoshima, Y. Y. & Yajima, J.
Biophys. J.   108 872-879   2014   [Refereed]
Measuring collective transport by defined numbers of processive and nonprocessive kinesin motors.
Furuta, K., Furuta, A., Toyoshima, Y.Y., Amino, M., Oiwa, K., & Kojima, H.
Proc Natl Acad Sci U S A.   110 501-506   2013   [Refereed]
Regulation of mitochondrial transport and inter-microtubule spacing by tau phosphorylation at the sites hyperphosphorylation in Alzheimer’s disease.
Shapasand, K., Uemura, I., Saito, T., Asano, T., Hata, K., Shibata, K., Toyoshima, Y.Y., Hasegawa, M. & Hisanaga, S.
J. Neurosci.   32 2430-2441   2012   [Refereed]
A single protofilament is sufficient to support unidirectional walking of dynein and kinesin.
Shibata, K., Miura, M., Watanabe, Y., Saito, K., Nishimura, A. Furuta, K. & Toyoshima, Y.Y.
PLoS one   7 e42990   2012   [Refereed]
Recombinant human cytoplasmic dynein heavy chain 1 and 2: Observation of dynein-2 motor activity in vitro.
Ichikawa, M., Watanabe, Y., Murayama, T. & Toyoshima, Y. Y.
FEBS Lett.   585 2419-2423   2011   [Refereed]
Simple method of synthesizing nickel–nitrilotriacetic acid gold nanoparticles with a narrow size distribution for protein labeling.
Kitai, T., Watanabe, Y., Toyoshima, Y.Y., Kobayashi, T., Murayama, T., Sakaue, H., Suzuki, H. & Takahagi, T.
Japanese Journal of Applied Physics   50 095002   2011   [Refereed]
Nucleotide-dependent behavior of single molecules of cytoplasmic dynein on microtubules in vitro.
Miura, M., Matsubara, A., Kobayashi, T., Edamatsu, M. & Toyoshima, Y.Y.
FEBS Lett.   584 2351-2355   2010   [Refereed]
Functional Dissection of LIS1 and NDEL1 Towards Understanding the Molecular Mechanisms of Cytoplasmic Dynein Regulation.
Torisawa, T., Nakayama, A., Furuta, K., Yamada, M., Hirotsune, S. & Toyoshima, Y. Y.
J. Biol.Chem   286 1959-1965   2010   [Refereed]
Inhibition of cytoplasmic dynein activity by CRMP-2 through a direct interaction.
Arimura, N., Hattori, A., Kimura, T., Nakamura , S., Funahashi, Y., Hirotsune, S., Furuta, K., Toyoshima, Y. Y. & Kaibuchi, K.
J Neurochem.   111 380-390   2009   [Refereed]
Minus-end-directed motor Ncd exhibits processive movement that is enhanced by microtubule bundling in vitro.
Furuta, K. & Toyoshima, Y. Y.
Current Biology   18 152-157   2008   [Refereed]
The dynein stalk head, the microtubule binding-domain of dynein: NMR assignment and ligand binding.
Shimizu, Y., Kato, Y., Morii, H., Edamatsu, M., Toyoshima, Y.Y. & Tanokura, M.
J. Biomol. NMR   41 89-96   2008   [Refereed]
Direction and speed of microtubule movements driven by kinesin motors arranged on catchin thick filaments.
Taba, T., Edamatsu, M., Toba, S., Shibata, K., Imafuku, Y., Toyoshima, Y.Y., Tawada, K. & Yamada, A.
Cell Motility and the Cytoskeleton   65 816-826   2008   [Refereed]

Misc

 
TOYOSHIMA Yoko
高分子   59(11)    Nov 2010
TOYOSHIMA Yoko, SOKABE Masahiro
Seibutsu Butsuri   49(3) 153-155   May 2009
TOYOSHIMA Yoko Y.
Biophysics   48(1) 58-59   Jan 2008
豊島 陽子
Biophysics   45(4)    Jul 2005

Books etc

 
Motile and enzymatic properties of native dynein molecules
Toyoshima, Y.Y. and Higuchi, H. (Part:Contributor, Handbook of Dynein)
Pan Stanford Publishing   2012