池上大悟 (Daigo Ikegami) - マイポータル

基本情報

所属: 湘南医療大学薬学部　薬理学研究室講師

研究者番号: 30619747
J-GLOBAL ID: 202401007719032320
researchmap会員ID: R000072761

研究キーワード

研究分野

経歴

2022年4月 - 現在

湘南医療大学, 薬学部薬理学研究室, 講師
2017年4月 - 2022年3月

アリゾナ大学, 薬学部, 研究員
2015年4月 - 2017年3月

マイアミ大学, 医学部麻酔科, 研究員
2011年8月 - 2015年3月

星薬科大学, 薬理学教室, 助教
2010年4月 - 2011年7月

国立がん研究センター, エピゲノム解析分野 (発がん研究部), 研究員

論文

Sirtuin 3 Mediated by Spinal cMyc-Enhancer of Zeste Homology 2 Pathway Plays an Important Role in Human Immunodeficiency Virus-Related Neuropathic Pain Model.

Xun Zhu, Hyun Yi, Jun Gu, Shue Liu, Kentaro Hayashi, Daigo Ikegami, Marta Pardo, Michal Toborek, Sabita Roy, Heng Li …

Anesthesia and analgesia 2024年3月6日
Chronic pain recruits hypothalamic dynorphin/kappa opioid receptor signalling to promote wakefulness and vigilance.

Hisakatsu Ito, Edita Navratilova, Barbora Vagnerova, Moe Watanabe, Carol Kopruszinski, Luiz H Moreira de Souza, Xu Yue, Daigo Ikegami, Aubin Moutal, Amol Patwardhan …

Brain : a journal of neurology 146(3) 1186-1199 2023年3月1日
Dysregulation of serum prolactin links the hypothalamus with female nociceptors to promote migraine.

Moe Watanabe, Caroline M Kopruszinski, Aubin Moutal, Daigo Ikegami, Rajesh Khanna, Yanxia Chen, Sarah Ross, Kimberly Mackenzie, Jennifer Stratton, David W Dodick …

Brain : a journal of neurology 145(8) 2894-2909 2022年8月27日
A prolactin-dependent sexually dimorphic mechanism of migraine chronification.

Daigo Ikegami, Edita Navratilova, Xu Yue, Aubin Moutal, Caroline M Kopruszinski, Rajesh Khanna, Amol Patwardhan, David W Dodick, Frank Porreca

Cephalalgia : an international journal of headache 42(3) 197-208 2022年3月
Mitochondrial biogenesis factor PGC-1α suppresses spinal morphine tolerance by reducing mitochondrial superoxide.

Yuta Kashiwagi, Hyun Yi, Shue Liu, Keiya Takahashi, Kentaro Hayashi, Daigo Ikegami, Xun Zhu, Jun Gu, Shuanglin Hao

Experimental neurology 339 113622-113622 2021年5月
Phosphorylated CCAAT/Enhancer Binding Protein β Contributes to Rat HIV-Related Neuropathic Pain: In Vitro and In Vivo Studies.

Hyun Yi, Shue Liu, Yuta Kashiwagi, Daigo Ikegami, Wan Huang, Hirotsugu Kanda, Takafumi Iida, Ching-Hang Liu, Keiya Takahashi, David A Lubarsky …

The Journal of neuroscience : the official journal of the Society for Neuroscience 38(3) 555-574 2018年1月17日
Activation of ventral tegmental area dopaminergic neurons reverses pathological allodynia resulting from nerve injury or bone cancer.

Moe Watanabe, Michiko Narita, Yusuke Hamada, Akira Yamashita, Hideki Tamura, Daigo Ikegami, Takashige Kondo, Tatsuto Shinzato, Takatsune Shimizu, Yumi Fukuchi …

Molecular pain 14 1744806918756406-1744806918756406 2018年
Chronic treatment of non-small-cell lung cancer cells with gefitinib leads to an epigenetic loss of epithelial properties associated with reductions in microRNA-155 and -200c.

Michiko Narita, Eri Shimura, Atsumi Nagasawa, Toshiki Aiuchi, Yukari Suda, Yusuke Hamada, Daigo Ikegami, Chizuru Iwasawa, Kazuhiko Arakawa, Katsuhide Igarashi …

PloS one 12(2) e0172115 2017年
[The importance of epigenetic analysis in pain].

Daigo Ikegami, Katsuhide Igarashi, Maky Otsuka, Naoko Kuzumaki, Minoru Narita

Nihon yakurigaku zasshi. Folia pharmacologica Japonica 147(4) 225-9 2016年4月
[Molecular Understanding of the Acquisition of Resistance to Anti-cancer Drugs Associated with the Exacerbation of Cancer].

Naoko Kuzumaki, Michiko Narita, Daigo Ikegami, Minoru Narita

Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 136(5) 699-703 2016年
Reduced Adult Hippocampal Neurogenesis and Cognitive Impairments following Prenatal Treatment of the Antiepileptic Drug Valproic Acid.

Berry Juliandi, Kentaro Tanemura, Katsuhide Igarashi, Takashi Tominaga, Yusuke Furukawa, Maky Otsuka, Noriko Moriyama, Daigo Ikegami, Masahiko Abematsu, Tsukasa Sanosaka …

Stem cell reports 5(6) 996-1009 2015年12月8日
[Pain and emotional dysregulation: Cellular memory due to pain].

Minoru Narita, Moe Watanabe, Yusuke Hamada, Hideki Tamura, Daigo Ikegami, Naoko Kuzumaki, Katsuhide Igarashi

Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology 35(4) 89-95 2015年8月
Epigenetic mechanisms of chronic pain.

Giannina Descalzi, Daigo Ikegami, Toshikazu Ushijima, Eric J Nestler, Venetia Zachariou, Minoru Narita

Trends in neurosciences 38(4) 237-46 2015年4月
Possible involvement of activated locus coeruleus-noradrenergic neurons in pain-related sleep disorders.

Keito Koh, Asami Hamada, Yusuke Hamada, Makoto Yanase, Mamiko Sakaki, Kazuki Someya, Michiko Narita, Naoko Kuzumaki, Daigo Ikegami, Hiroyasu Sakai …

Neuroscience letters 589 200-6 2015年3月4日
Neutrophil recruitment is critical for 5-fluorouracil-induced diarrhea and the decrease in aquaporins in the colon.

Hiroyasu Sakai, Atsunobu Sagara, Kenjiro Matsumoto, Ara Jo, Akiko Hirosaki, Kazuhide Takase, Ryoto Sugiyama, Ken Sato, Daigo Ikegami, Syunji Horie …

Pharmacological research 87 71-9 2014年9月
Changes in circadian rhythm for mRNA expression of melatonin 1A and 1B receptors in the hypothalamus under a neuropathic pain-like state.

Masahiko Odo, Keito Koh, Tomohiko Takada, Akira Yamashita, Michiko Narita, Naoko Kuzumaki, Daigo Ikegami, Hiroyasu Sakai, Masako Iseki, Eiichi Inada …

Synapse (New York, N.Y.) 68(4) 153-8 2014年4月
Possibility of a novel therapy for neuropathic pain by specific histone modification of astrocytic chemokines in the spinal cord

Daigo Ikegami, Kaori Ohi, Michiko Narita, Akira Yamashita, Naoko Kuzumaki, Hideyuki Okano, Toshikazu Ushijima, Minoru Narita

JOURNAL OF PHARMACOLOGICAL SCIENCES 124 100P-100P 2014年
Analysis of sleep disorders under pain using an optogenetic tool: possible involvement of the activation of dorsal raphe nucleus-serotonergic neurons.

Hisakatsu Ito, Makoto Yanase, Akira Yamashita, Chigusa Kitabatake, Asami Hamada, Yuki Suhara, Michiko Narita, Daigo Ikegami, Hiroyasu Sakai, Mitsuaki Yamazaki …

Molecular brain 6 59-59 2013年12月26日
[Understanding of the psychiatry in palliative care: dysfunction of the rewarding system under the pain state associated with exacerbating pain].

Daigo Ikegami, Akira Yamashita, Minoru Narita

Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology 33(5-6) 199-204 2013年11月
Changes in the circadian rhythm of mRNA expression for µ-opioid receptors in the periaqueductal gray under a neuropathic pain-like state.

Tomohiko Takada, Akira Yamashita, Akitoshi Date, Makoto Yanase, Yuki Suhara, Asami Hamada, Hiroyasu Sakai, Daigo Ikegami, Masako Iseki, Eiichi Inada …

Synapse (New York, N.Y.) 67(5) 216-23 2013年5月

もっとみる

MISC

Changes in the expression of glial fibrillary acidic protein in the hypothalamus in a mouse model of cancer cachexia

Yoshihiko Tasaki, Masami Suzuki, Shinsuke Shibata, Daigo Ikegami, Minoru Narita, Yasuhito Uezono

JOURNAL OF PHARMACOLOGICAL SCIENCES 121 94P-94P 2013年
Analysis for molecular mechanism of hippocampal neurogenesis associated with epigenetic modulation under enriched environment

Atsumi Nagasawa, Naoko Kuzumaki, Michiko Narita, Daigo Ikegami, Hideyuki Takeshima, Toshikazu Ushijima, Mitsuaki Yamazaki, Minoru Narita

NEUROSCIENCE RESEARCH 71 E240-E240 2011年
Impairment of hippocampal neurogenesis by normal aging associated with epigenetic modification

Naoko Kuzumaki, Minoru Narita, Daigo Ikegami, Michiko Narita, Satoshi Imai, Takayuki Ando, Hideyuki Takeshima, Toshikazu Ushijima, Tsutomu Suzuki

JOURNAL OF PHARMACOLOGICAL SCIENCES 112 88P-88P 2010年

所属学協会

共同研究・競争的資金等の研究課題

体内時計である睡眠中枢の機能改善により神経障害性疼痛は軽快するか

日本学術振興会科学研究費助成事業基盤研究(C) 2014年4月 - 2017年3月

山崎光章, 酒井寛泰, 池上大悟, 竹村佳記, 成田年
神経障害性疼痛下におけるｍｉＲＮＡ変化の網羅的解析

日本学術振興会科学研究費助成事業若手研究(B) 2012年4月 - 2015年3月

池上大悟