論文

査読有り
2010年8月

A case of dermatomyositis with "liver disease associated with rheumatoid diseases" positive for anti-liver-kidney microsome-1 antibody

CLINICAL RHEUMATOLOGY
  • Shinji Noda
  • ,
  • Yoshihide Asano
  • ,
  • Zenshiro Tamaki
  • ,
  • Tomonori Takekoshi
  • ,
  • Makoto Sugaya
  • ,
  • Shinichi Sato

29
8
開始ページ
941
終了ページ
943
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1007/s10067-010-1397-3
出版者・発行元
SPRINGER LONDON LTD

We reported a case of dermatomyositis (DM) with liver disturbance in a 50-year-old Japanese female. She presented with fever, muscle weakness, and typical DM rashes. On clinical and serological examinations, the liver impairment was initially diagnosed as probable autoimmune hepatitis, which was denied by a histological study despite positive anti-liver-kidney microsome-1 antibody. Finally, she was diagnosed as having DM with "liver disease associated with rheumatoid diseases", and treatment with oral prednisone (40 mg/day) achieved normalization of liver and muscle enzyme levels as well as improvement of symptoms associated with DM. Liver involvement in patients with polymyositis (PM)/DM has not been well described and is considered to be uncommon. Full clarification of the etiology of liver impairment with a histological examination in collagen diseases including PM/DM is useful to determine the proper dose of corticosteroids for the treatment of collagen diseases and their liver complications.

Web of Science ® 被引用回数 : 2

リンク情報
DOI
https://doi.org/10.1007/s10067-010-1397-3
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/20179980
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000279459700017&DestApp=WOS_CPL

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