2011年1月
Sake Lees Fermented with Lactic Acid Bacteria Prevents Allergic Rhinitis-Like Symptoms and IgE-Mediated Basophil Degranulation
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
- 巻
- 75
- 号
- 1
- 開始ページ
- 140
- 終了ページ
- 144
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1271/bbb.100541
- 出版者・発行元
- TAYLOR & FRANCIS LTD
We tested the effect of oral administration of fermented sake lees with lactic acid bacteria (FESLAB) on a murine model of allergic rhinitis upon immunization and nasal sensitization with ovalbumin (OVA). We used Lactobacillus paracasei NPSRIk-4 (isolated from sake lees), and L. brevis NPSRIv-8 (from fermented milk) as starter strains to produce the FESLAB. Oral FESLAB administration resulted in the development of significantly fewer sneezing symptoms than those seen in sham control animals given sterile water. We also found that FESLAB suppressed the allergen-induced degranulation of RBL2H3 rat basophilic leukemia cells.
- リンク情報
- ID情報
-
- DOI : 10.1271/bbb.100541
- ISSN : 0916-8451
- eISSN : 1347-6947
- Web of Science ID : WOS:000287384100022