論文

査読有り
2012年

Porphyrins from a metagenomic library of the marine sponge Discodermia calyx

MOLECULAR BIOSYSTEMS
  • Rui He
  • ,
  • Toshiyuki Wakimoto
  • ,
  • Yuya Takeshige
  • ,
  • Yoko Egami
  • ,
  • Hiromichi Kenmoku
  • ,
  • Takuya Ito
  • ,
  • Bochu Wang
  • ,
  • Yoshinori Asakawa
  • ,
  • Ikuro Abe

8
9
開始ページ
2334
終了ページ
2338
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1039/c2mb25169h
出版者・発行元
ROYAL SOC CHEMISTRY

Marine sponges harbouring uncultured symbiotic bacteria are important sources of biologically active compounds. Since they would be interesting resources to explore unknown functional genes by means of a metagenomic approach, we constructed a metagenomic library of the Japanese marine sponge Discodermia calyx. The functional screening afforded the two clones producing porphyrins as red pigments. The isolation and structural elucidation of the red pigments revealed that the major red pigment was Zn-coproporphyrin III. The sequence data of the clones identified genes encoding glutamyl-tRNA reductase along with other ORFs related to porphyrin biosynthesis.

リンク情報
DOI
https://doi.org/10.1039/c2mb25169h
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000307014300011&DestApp=WOS_CPL
ID情報
  • DOI : 10.1039/c2mb25169h
  • ISSN : 1742-206X
  • Web of Science ID : WOS:000307014300011

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