2015年10月
Role and Regulation of Myeloid Zinc Finger Protein 1 in Cancer.
Journal of cellular biochemistry
- ,
- ,
- ,
- 巻
- 116
- 号
- 10
- 開始ページ
- 2146
- 終了ページ
- 54
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1002/jcb.25203
- 出版者・発行元
- WILEY-BLACKWELL
Myeloid zinc finger 1 (MZF1) belongs to the SCAN-Zinc Finger (SCAN-ZF) transcription factor family that has recently been implicated in a number of types of cancer. Although the initial studies concentrated on the role of MZF1 in myeloid differentiation and leukemia, the factor now appears to be involved in the etiology of major solid tumors such as lung, cervical, breast, and colorectal cancer. Here we discuss the regulation of MZF1 that mediated its recruitment and activation in cancer, concentrating on posttranslational modification by phosphorylation, and sumoylation, formation of promyelocytic leukemia nuclear bodies and its association with co-activators and co-repressors.
- リンク情報
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- DOI
- https://doi.org/10.1002/jcb.25203
- PubMed
- https://www.ncbi.nlm.nih.gov/pubmed/25903835
- PubMed Central
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7380561
- Web of Science
- https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000359809400004&DestApp=WOS_CPL
- ID情報
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- DOI : 10.1002/jcb.25203
- ISSN : 0730-2312
- eISSN : 1097-4644
- PubMed ID : 25903835
- PubMed Central 記事ID : PMC7380561
- Web of Science ID : WOS:000359809400004