WATANABE Eiji

J-GLOBAL         Last updated: Nov 19, 2019 at 11:47
 
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Name
WATANABE Eiji
Nickname
eijwat
E-mail
eijinibb.ac.jp
URL
http://www.nibb.ac.jp/neurophys/
Affiliation
National Institutes of Natural Sciences
Section
National Institute for Basic Biology
Job title
Associate Professor
Degree
Ph.D.(Osaka Univ)
Research funding number
30250252
Twitter ID
eijwat
ORCID ID
0000-0001-9089-8122

Research Areas

 
 

Published Papers

 
Abe Erinaand Yasugi Masakiand Takeuchi Hideakiand Watanabe Eijiand Kamei Yasuhiroand Yamamoto Hirotsugu
Optical Review      2019   [Refereed]
Eiji Watanabe, Eiji Watanabe, Akiyoshi Kitaoka, Kiwako Sakamoto, Kiwako Sakamoto, Masaki Yasugi, Kenta Tanaka
Frontiers in Psychology   9    Mar 2018   [Refereed]
© 2018 Watanabe, Kitaoka, Sakamoto, Yasugi and Tanaka. The cerebral cortex predicts visual motion to adapt human behavior to surrounding objects moving in real time. Although the underlying mechanisms are still unknown, predictive coding is one of...
Tsuyoshi Shimmura, Tsuyoshi Shimmura, Tsuyoshi Shimmura, Tsuyoshi Shimmura, Tomoya Nakayama, Tomoya Nakayama, Ai Shinomiya, Ai Shinomiya, Shoji Fukamachi, Masaki Yasugi, Eiji Watanabe, Eiji Watanabe, Takayuki Shimo, Takayuki Shimo, Takumi Senga, Takumi Senga, Toshiya Nishimura, Toshiya Nishimura, Minoru Tanaka, Minoru Tanaka, Minoru Tanaka, Yasuhiro Kamei, Yasuhiro Kamei, Kiyoshi Naruse, Kiyoshi Naruse, Takashi Yoshimura, Takashi Yoshimura, Takashi Yoshimura, Takashi Yoshimura
Nature Communications   8    Dec 2017   [Refereed]
© 2017 The Author(s). To cope with seasonal changes in the environment, organisms adapt their physiology and behavior. Although color perception varies among seasons, the underlying molecular basis and its physiological significance remain unclear...
Tomohiro Nakayasu, Masaki Yasugi, Soma Shiraishi, Seiichi Uchida, Eiji Watanabe
PLoS ONE   12    Apr 2017   [Refereed]
© 2017 Nakayasu et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source ar...
Tomohiro Nakayasu, Eiji Watanabe
Animal Cognition   17 559-575   Jan 2014   [Refereed]
In many social fish species, visual cues play an important role in inducing shoaling behaviour. The present study is the first to examine whether and how "biological motion" depicting a moving creature by means of only a small number of isolated p...
Takeshi Y. Hiyama, Takeshi Y. Hiyama, Masahide Yoshida, Masahito Matsumoto, Ryoko Suzuki, Takashi Matsuda, Takashi Matsuda, Eiji Watanabe, Eiji Watanabe, Masaharu Noda, Masaharu Noda
Cell Metabolism   17 507-519   Apr 2013   [Refereed]
Salt homeostasis is essential to survival, but brain mechanisms for salt-intake control have not been fully elucidated. Here, we found that the sensitivity of Naxchannels to [Na+]ois dose-dependently enhanced by endothelin-3 (ET-3). Naxchannels be...
Wataru Matsunaga, Eiji Watanabe
Scientific Reports   2    Jan 2012   [Refereed]
Visual motion cues are one of the most important factors for eliciting animal behaviour, including predator-prey interactions in aquatic environments. To understand the elements of motion that cause such selective predation behaviour, we used a vi...
Wataru Matsunaga, Eiji Watanabe
Neuroscience Research   71 e148   Sep 2011   [Refereed]
Eiji Watanabe, Wataru Matsunaga, Akiyoshi Kitaoka
Vision Research   50 2381-2390   Nov 2010   [Refereed]
The perceived relative position of a moving object is frequently shifted as compared to the relative position of the object in the real world. The illusions have traditionally been explained by temporal models that influence the perceptual latency...
Wataru Matsunaga, Eiji Watanabe
Behavioural Processes   85 142-150   Oct 2010   [Refereed]
Habituation to novel environments is frequently studied to analyze cognitive phenotypes in animals, and an open-field test is generally conducted to investigate the changes that occur in animals during habituation. The test has not been used in be...
Takeshi Y. Hiyama, Takeshi Y. Hiyama, Shinichi Matsuda, Akihiro Fujikawa, Masahito Matsumoto, Eiji Watanabe, Eiji Watanabe, Hiroshi Kajiwara, Fumio Niimura, Masaharu Noda, Masaharu Noda
Neuron   66 508-522   May 2010   [Refereed]
Naxis the sodium-level sensor of body fluids in the brain involved in sodium homeostasis. Nax-knockout mice do not stop ingesting salt even when dehydrated. Here we report a case with clinical features of essential hypernatremia without demonstrab...
Eiji Watanabe, Wataru Matsunaga, Akiyoshi Kitaoka
Neuroscience Research   68 e270   Jan 2010   [Refereed]
Sachiko Aono, Yoshihito Tokita, Fumiko Matsui, Atsuhiko Oohira, Eiji Watanabe
Neuroscience Research   68 e421   Jan 2010   [Refereed]
Takeshi{\_}Y. Hiyama, Shinichi Matsuda, Akihiro Fujikawa, Masahito Matsumoto, Eiji Watanabe, Hiroshi Kajiwara, Fumio Niimura, Masaharu Noda
Neuroscience Research   68 e417   Jan 2010   [Refereed]
Wataru Matsunaga, Eiji Watanabe
Neuroscience Research   68 e268   Jan 2010   [Refereed]
Wataru Matsunaga, Eiji Watanabe
Neuroscience Research   65 S227   Jan 2009   [Refereed]
Hidetada Shimizu, Hidetada Shimizu, Eiji Watanabe, Eiji Watanabe, Takeshi Y. Hiyama, Takeshi Y. Hiyama, Ayano Nagakura, Ayano Nagakura, Akihiro Fujikawa, Haruo Okado, Yuchio Yanagawa, Kunihiko Obata, Masaharu Noda, Masaharu Noda
Neuron   54 59-72   Apr 2007   [Refereed]
Sodium (Na) homeostasis is crucial for life, and Na levels in body fluids are constantly monitored in the brain. The subfornical organ (SFO) is the center of the sensing responsible for the control of salt-intake behavior, where Naxchannels are ex...
Hidetada Shimizu, Takeshi Y. Hiyama, Ayano Nagakura, Akihiro Fujikawa, Eiji Watanabe, Masaharu Noda
Neuroscience Research   58 S79   Jan 2007   [Refereed]
Ayano Nagakura, Takeshi Y. Hiyama, Eiji Watanabe, Masaharu Noda
Neuroscience Research   58 S79   Jan 2007   [Refereed]
Eiji Watanabe, Eiji Watanabe, Takeshi Y. Hiyama, Takeshi Y. Hiyama, Hidetada Shimizu, Hidetada Shimizu, Ryuji Kodama, Ryuji Kodama, Noriko Hayashi, Seiji Miyata, Yuchio Yanagawa, Kunihiko Obata, Masaharu Noda, Masaharu Noda, Masaharu Noda
American Journal of Physiology - Regulatory Integrative and Comparative Physiology   290    Mar 2006   [Refereed]
Naxis an atypical sodium channel that is assumed to be a descendant of the voltage-gated sodium channel family. Our recent studies on the Nax-gene-targeting mouse revealed that Naxchannel is localized to the circumventricular organs (CVOs), the ce...
Kazue Niisato, Kazue Niisato, Akihiro Fujikawa, Shoji Komai, Takafumi Shintani, Eiji Watanabe, Gaku Sakaguchi, Goro Katsuura, Toshiya Manabe, Toshiya Manabe, Toshiya Manabe, Masaharu Noda, Masaharu Noda
Journal of Neuroscience   25 1081-1088   Feb 2005   [Refereed]
Although protein tyrosine phosphatases (PTPs) are expressed abundantly in the brain, their roles in synaptic plasticity have not been well elucidated. In this study, we have examined the physiological functions of Ptprz, which is a receptor-type P...
Takeshi Y. Hiyama, Takeshi Y. Hiyama, Eiji Watanabe, Eiji Watanabe, Haruo Okado, Masaharu Noda, Masaharu Noda, Masaharu Noda
Journal of Neuroscience   24 9276-9281   Oct 2004   [Refereed]
Dehydration causes an increase in the sodium (Na) concentration and osmolarity of body fluid. For Na homeostasis of the body, controls of Na and water intake and excretion are of prime importance. However, the system for sensing the Na level withi...
Uno Watanabe, Tsuyoshi Shimura, Noritaka Sako, Jun Ichi Kitagawa, Tomio Shingai, Eiji Watanabe, Masaharu Noda, Takashi Yamamoto
Brain Research   967 247-256   Mar 2003   [Refereed]
The Naxchannel, a subfamily of voltage-gated sodium channels, is thought to be a specific sodium receptor in the central nervous system. Our previous study revealed that Nax-gene-deficient mice consumed excessive amounts of NaCl even under water-d...
Uno Watanabe, Tsuyoshi Shimura, Noritaka Sako, Jun-ichi Kitagawa, Tomio Shingai, Eiji Watanabe, Masaharu Noda, Takashi Yamamoto
Brain Research   967(1-2) 247   Mar 2003   [Refereed]
Mohamad Zubair, Eiji Watanabe, Eiji Watanabe, Eiji Watanabe, Masahide Fukada, Masahide Fukada, Masaharu Noda, Masaharu Noda, Masaharu Noda
European Journal of Neuroscience   15 807-814   Dec 2002   [Refereed]
We report on transgenic mouse lines in which several sensory systems in the brain are specifically visualized genetically. We employed GAP-lacZ as an axon-targeted reporter protein that was constructed by fusing the membrane-anchoring domain of th...
Eiji Watanabe, Takeshi Y. Hiyama, Takeshi Y. Hiyama, Ryuji Kodama, Masaharu Noda
Neuroscience Letters   330 109-113   Sep 2002   [Refereed]
Naxis an extracellular sodium-level-sensitive sodium channel expressed in the circumventricular organs in the brain, essential loci for the sodium-level homeostasis in body fluids. Here, we examined the localization of Naxthroughout the visceral o...
Eiji Watanabe, Takeshi Y. Hiyama, Ryuji Kodama, Masaharu Noda
Neuroscience Letters   330(1) 109   Sep 2002   [Refereed]
Takeshi Y. Hiyama, Eiji Watanabe, Kentaro Ono, Kiyotoshi Inenaga, Michael M. Tamkun, Shigeru Yoshida, Shigeru Yoshida, Masaharu Noda
Nature Neuroscience   5 511-512   Jan 2002   [Refereed]
Eiji Watanabe, Akihiro Fujikawa, Haruyuki Matsunaga, Yasunobu Yasoshima, Noritaka Sako, Takashi Yamamoto, Chika Saegusa, Masaharu Noda
The Journal of Neuroscience   20(20) 7743-7751   Oct 2000   [Refereed]
Na(v)2/NaG is a putative sodium channel, whose physiological role has long been an enigma. We generated Na(v)2 gene-deficient mice by inserting the lacZ gene. Analysis of the targeted mice allowed us to identify Na(v)2-producing cells by examining...
Yoko Yasuda, Yoko Yasuda, Yoshihito Tokita, Sachiko Aono, Fumiko Matsui, Takao Ono, Shin Ichi Sonta, Eiji Watanabe, Yasuo Nakanishi, Atsuhiko Oohira
Neuroscience Research   32(4) 313-322   Dec 1998   [Refereed]
Neuroglycan C (NGC) is a 150 kDa transmembrane chondroitin sulfate proteoglycan with a 120 kDa core glycoprotein that was originally isolated from the developing rat brain. A rabbit antiserum, raised against a recombinant polypeptide representing ...
Ritsuko Katoh-Semba, Motoko Matsuda, Eiji Watanabe, Nobuaki Maeda, Atsuhiko Oohira
Neuroscience Research   31(4) 273-282   Aug 1998   [Refereed]
The distribution of neurocan-like and 6B4 proteoglycan-like immunoreactivities in the rat embryo was investigated from gestational days 10.5-15.5 with monoclonal antibody 1G2 or 6B4 that immunoreacted with neurocan and 6B4 proteoglycan, respective...
Ritsuko Katoh-Semba, Motoko Matsuda, Eiji Watanabe, Nobuaki Maeda, Atsuhiko Oohira
Neuroscience Research   31(4) 273   Aug 1998   [Refereed]
Takafumi Shintani, Eiji Watanabe, Nobuaki Maeda, Masaharu Noda
Neuroscience Letters   247(2/3) 135-138   May 1998   [Refereed]
PTPζ/RPTPβ is a receptor-like protein tyrosine phosphatase expressed as a chondroitin sulfate proteoglycan. We generated mice in which the PTPζ gene was replaced by the LacZ gene by gene targeting. Analysis of heterozygous PTPζ-targeted mice allow...
Takafumi Shintani, Eiji Watanabe, Nobuaki Maeda, Masaharu Noda
Neuroscience Letters   247(2-3) 135   May 1998   [Refereed]
Fumiko Matsui, Masako Nishizuka, Yoko Yasuda, Sachiko Aono, Eiji Watanabe, Atsuhiko Oohira
Brain Research   790(1/2) 45-51   Apr 1998   [Refereed]
Neurocan is a nervous tissue-unique chondroitin sulfate proteoglycan (CSPG) whose expression and proteolytic cleavage are developmentally regulated. In the adult rat brain, neurocan is completely cleaved into some proteoglycan fragments including ...
Fumiko Matsui, Masako Nishizuka, Yoko Yasuda, Sachiko Aono, Eiji Watanabe, Atsuhiko Oohira
Brain Research   790(1-2) 45   Apr 1998   [Refereed]
Takafumi Shintani, Eiji Watanabe, Nobuaki Maeda, Masaharu Noda
Neuroscience Research   31 S150   Jan 1998   [Refereed]
Eiji Watanabe, Chika Saegusa, Haruyuki Matsunaga, Yoheved Berwald-Netter, Masaharu Noda
Neuroscience Research   31 S58   Jan 1998   [Refereed]
Yoko Yasuda, Yoshihito Tokita, Sachiko Aono, Fumiko Matsui, Takao Ono, Shin-ichi Sonta, Eiji Watanabe, Yasuo Nakanishi, Atsuhiko Oohira
Neuroscience Research   32(4) 313   1998   [Refereed]
E. Watanabe, E. Watanabe, E. Watanabe, F. Matsui, H. Keino, K. Ono, Y. Kushima, Y. Kushima, M. Noda, A. Oohira
Journal of Neuroscience Research   44 84-96   Apr 1996   [Refereed]
Monoclonal antibodies were raised to membrane-bound proteoglycans derived from rat brain and three monoclonal antibodies that recognized a 200-kDa heparan sulfate proteoglycan (designated H5-PG) with a core glycoprotein of 140 kDa were obtained. T...
Eiji Watanabe, Eiji Watanabe, Nobuaki Maeda, Fumiko Matsui, Yoichi Kushima, Yoichi Kushima, Masaharu Noda, Atsuhiko Oohira
Journal of Biological Chemistry   270(45) 26876-26882   Nov 1995   [Refereed]
Monoclonal antibodies were raised to membrane-bound proteoglycans derived from rat brain, and four monoclonal antibodies that recognized a 150-kDa chondroitin sulfate proteoglycan with a core glycoprotein of 120 kDa were obtained. Immunohistologic...
Atsuhiko Oohira, Yoichi Kushima, Fumiko Matsui, Eiji Watanabe
Neuroscience Letters   189(1) 25-28   Apr 1995   [Refereed]
Alzheimer's β-amyloid precursor related proteins bearing chondroitin sulfate chains were detected in the conditioned media of primary cultured astrocytes obtained from fetal rat brains by Western blotting using the monoclonal antibody 22C11 agains...
Atsuhiko Oohira, Yoichi Kushima, Fumiko Matsui, Eiji Watanabe
Neuroscience Letters   189(1) 25   Apr 1995   [Refereed]
Eiji Watanabe, Sachiko Aono, Fumiko Matsui, Yasukazu Yamada, Yasukazu Yamada, Ichiro Naruse, Ichiro Naruse, Atsuhiko Oohira
European Journal of Neuroscience   7 547-554   Jan 1995   [Refereed]
Neurocan is a developmentally regulated chondroitin sulphate proteoglycan in the rat brain. In the present study, spatiotemporal patterns of expression of neurocan and the corresponding mRNA were examined in the developing cortical barrel field of...
Hiroaki Kobayashi, Eiji Watanabe, Eiji Watanabe, Fujio Murakami
Developmental Biology   168(2) 383-394   Jan 1995   [Refereed]
Axons in the central nervous system of mature mammals generally fail to regenerate following injury. Although the reason for this regenerative failure remains unknown, several lines of evidence suggest that it is due to nonpermissiveness of oligod...
Fumiko Matsui, Eiji Watanabe, Atsuhiko Oohira
Neurochemistry International   25(5) 425-431   Jan 1994   [Refereed]
Neurocan is a brain-unique chondroitin sulfate proteoglycan (CSPG) whose expression and proteolytic cleavage are developmentally regulated. One of the proteolytic products (C-terminal half) is known to be a CSPG with a 150 kDa core glycoprotein (C...
Atsuhiko Oohira, Ritsuko Katoh-Semba, Eiji Watanabe, Fumiko Matsui
Neuroscience Research   20(3) 195-207   Jan 1994   [Refereed]
The occurrence of multiple proteoglycan species is a characteristic of the brain. The structural features of individually characterized proteoglycans in the brain are first introduced in brief, then some examples are shown that suggest a relations...
Eiji Watanabe, Hiroshi Hosokawa, Hiroaki Kobayashi, Fujio Murakami
European Journal of Neuroscience   6 1354-1361   Jan 1994   [Refereed]
Accumulating evidence suggests that an inhibitory influence of the environment on growth cones plays a crucial role in development and regeneration of neuronal projections. Oligodendrocyte‐associated neurite growth inhibiting substance is one of t...
F. Murakami, H. Kobayashi, E. Watanabe
Biomedical Research   15 113-117   Jan 1994
Axons in the central nervous system of mature mammals generally fail to regenerate following injury. Several lines of evidence suggest that this regenerative failure is largely due to non-permissiveness of oligodendrocytes for axonal elongation. W...
A. Oohira, F. Matsui, E. Watanabe, Y. Kushima, N. Maeda
Neuroscience   60(1) 145-157   Jan 1994   [Refereed]
The mammalian brain contains many species of proteoglycan. To identify each proteoglycan species, we have raised monoclonal antibodies against soluble chondroitin sulfate proteoglycans purified from 10-day-old rat brains. One monoclonal antibody, ...
Fumiko Matsui, Eiji Watanabe, Atsuhiko Oohira
Neuroscience Research Supplements   19 S123   Jan 1994   [Refereed]
Eiji Watanabe, Fumiko Matsui, Hiroomi Keino, Yoichi Kushima, Atsuhiko Oohira
Neuroscience Research Supplements   19 S126   Jan 1994   [Refereed]
Hiroaki Kobayashi, Eiji Watanabe, Fujio Murakami
Neuroscience Research Supplements   17 173   Jan 1992   [Refereed]
Eiji Watanabe, Kei Naruse, Hiroaki Kobayashi, Takashi Uratani, Fujio Murakami
Neuroscience Research Supplements   14 S33   Jan 1991   [Refereed]
Eiji Watanabe, Fujio Murakami
Neuroscience Research   8(2) 83-99   Jan 1990   [Refereed]
Chick neocortical cells were cultured on cryostat tissue sections of the brain. Cells preferentially attached to the gray matter of adult rat central nervous system (CNS) tissues. In contrast, they attached to any part of the brain when cultured o...
F. Murakami, E. Watanabe
Biomedical Research   10 159-161   Dec 1989
Although in vitro culture of neuronal cell has been successfully carried out to study cell-cell and cell-substrata interactions, conventional culture methods are disadvantageous to understanding regional differences of the interactions. Therefore,...
Eiji Watanabe, Fujio Murakami
Neuroscience Letters   97 69-74   Feb 1989   [Refereed]
Dissociated chick neocortical neurons were cultured on cryostat sections of the rat central nervous system. The neurons adhered to and grew on the gray matter of the tissue derived from various parts of the central nervous system (CNS), but were n...
E. Watanabe, S. C. Fujita, F. Murakami, M. Hayashi, M. Matsumura
Neuroscience   29 645-657   Jan 1989   [Refereed]
A monoclonal antibody was obtained by immunizing mice with an extract of monkey brain. The monoclonal antibody 473 stained a small subpopulation of neurons in various regions of monkey and rat central nervous system. The perimeters of neuronal som...
Eiji Watanabe, Motoharu Hayashi, Michikazu Matsumura, Shinobu C. Fujita
Neuroscience Research Supplements   5 S41   Jan 1987   [Refereed]

Misc

 
Regional difference of cell adhesion onto tissue substrata from rat central nerous system
Biomedical Research   10 159-161   1989
Development of Brain and Proteoglycan
Connective Tissue   25 207-212   1993
A heparan sulfate proteoglycan associated with growing parallel fibers of granule cells in the rat cerebellar cortex.
Journal of Brain Science   22 67-75   1996
Low density, but not high density, C6 glioma cells Support dorsal root ganglion and Sympathetic ganglion neurite out growth
European Journal of Neuroscience   6 1354-1361   1994
A monoclonal antibody idenfies a novel epitope surrounding a subpopulation of the mammalian central neurons
Neuroscience   29 645-657   1989

Books etc

 
Regulation of cell adhesion and neurite outgrowth by inhibitory factor(s) in the CNS white matter
Molecular basis of neuronal connectivity   1992   

Research Grants & Projects

 
Study on Nax Sodium channel
Project Year: 1997   
Brain function regulated by glial cells
Project Year: 1985   
Vision of human and medaka fish
Project Year: 2008   
psychophysics of human and medaka fish