論文

査読有り
2011年3月

The cyclins: a family of widely expressed tumor antigens?

EXPERT REVIEW OF VACCINES
  • Michael S. von Bergwelt-Baildon
  • ,
  • Eisei Kondo
  • ,
  • Nela Klein-Gonzalez
  • ,
  • Clemens M. Wendtner

10
3
開始ページ
389
終了ページ
395
記述言語
英語
掲載種別
DOI
10.1586/ERV.10.170
出版者・発行元
EXPERT REVIEWS

Continuous cell division is a hallmark of cancer and cell-cycle regulators therefore represent relevant target molecules for tumor therapy. Among these targets the cyclins are of particular interest as they are overexpressed in various tumor entities with little expression in normal tissue. Here we review evidence that these molecules are recognized by the immune system, summarize why cyclins A, B and D in particular appear to be interesting targets for active and passive immunotherapy, and discuss whether the entire family could be an interesting novel class of tumor antigens for cancer treatment and prevention.

Web of Science ® 被引用回数 : 10

リンク情報
DOI
https://doi.org/10.1586/ERV.10.170
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000289767100017&DestApp=WOS_CPL
URL
http://www.scopus.com/inward/record.url?eid=2-s2.0-79953241925&partnerID=MN8TOARS
URL
http://orcid.org/0000-0003-0995-9405

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